Search Results - "Qiao, Yongbo"
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Self-assembling ferritin nanoparticles coupled with linear sequences from canine distemper virus haemagglutinin protein elicit robust immune responses
Published in Journal of nanobiotechnology (10-01-2022)“…Canine distemper virus (CDV), which is highly infectious, has caused outbreaks of varying scales in domestic and wild animals worldwide, so the development of…”
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Expression and evaluation of porcine circovirus type 2 capsid protein mediated by recombinant adeno-associated virus 8
Published in Journal of veterinary science (Suwŏn-si, Korea) (01-01-2021)“…Porcine circovirus type 2 (PCV2) is an important infectious pathogen implicated in porcine circovirus-associated diseases (PCVAD), which has caused significant…”
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Effects of insulin on transcriptional response and permeability in an in vitro model of human blood‐brain barrier
Published in Journal of cellular biochemistry (01-07-2018)“…Alzheimer's disease (AD) is the most prevalent form of dementia worldwide and is an emerging global epidemic. Active and passive immune therapies targeting…”
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Expression and evaluation of porcine circovirus type 2 capsid protein mediated by recombinant adeno-associated virus 8
Published in Journal of veterinary science (Suwŏn-si, Korea) (2021)“…Background: Porcine circovirus type 2 (PCV2) is an important infectious pathogen implicated in porcine circovirus-associated diseases (PCVAD), which has caused…”
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5
A self-assembling nanoparticle vaccine targeting the conserved epitope of influenza virus hemagglutinin stem elicits a cross-protective immune response
Published in Nanoscale (24-02-2022)“…Various vaccine strategies have been developed to provide broad protection against diverse influenza viruses. The hemagglutinin (HA) stem is the major…”
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Broad and potent bispecific neutralizing antibody gene delivery using adeno-associated viral vectors for passive immunization against HIV-1
Published in Journal of controlled release (10-10-2021)“…Broadly neutralizing antibodies (bNAbs) possess favorable safety, and passive immunization using these can prevent or control human immunodeficiency virus type…”
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Hemagglutinin‐based DNA vaccines containing trimeric self‐assembling nanoparticles confer protection against influenza
Published in Journal of leukocyte biology (01-09-2022)“…Influenza viruses continue to threaten public health, and currently available vaccines provide insufficient immunity against seasonal and pandemic influenza…”
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A biepitope, adjuvant-free, self-assembled influenza nanovaccine provides cross-protection against H3N2 and H1N1 viruses in mice
Published in Nano research (2022)“…Currently, the incorporation of multiple epitopes into vaccines is more desirable than the incorporation of a single antigen for universal influenza vaccine…”
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Identification of Linear Peptide Immunogens with Verified Broad-spectrum Immunogenicity from the Conserved Regions within the Hemagglutinin Stem Domain of H1N1 Influenza Virus
Published in Immunological investigations (17-02-2022)“…Influenza A viruses (IAVs) induce acute respiratory disease and cause severe epidemics and pandemics. Since IAVs exhibit antigenic variation and genome…”
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Effects of poly(I:C) and MF59 co‐adjuvants on immunogenicity and efficacy of survivin polypeptide immunogen against melanoma
Published in Journal of cellular physiology (01-06-2018)“…Malignant tumors pose a public health problem that jeopardizes human life and quality of living. At present, tumor vaccines in clinical research typically are…”
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A novel small molecule displays two different binding modes during inhibiting H1N1 influenza A virus neuraminidases
Published in Journal of structural biology (01-05-2018)“…[Display omitted] •Two different mechanism played by 7a during the inhibition of A/Puerto Rico/8/34 (H1N1) NA and A/California/04/09 (H1N1) NA.•The flexibility…”
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Multiple Antigenic Peptide System Coupled with Amyloid Beta Protein Epitopes As An Immunization Approach to Treat Alzheimer’s Disease
Published in ACS chemical neuroscience (19-06-2019)“…Latest studies suggest that Alzheimer’s disease (AD) is one of the “four big killers” that threaten the health of the elderly. AD affects about 46 million…”
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Humanization and directed evolution of the selenium-containing scFv phage abzyme
Published in RSC advances (01-01-2018)“…According to the binding site structure and the catalytic mechanism of the native glutathione peroxidase (GPX), three glutathione derivatives, GSH-S-DNP butyl…”
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Screening HCV genotype-specific epitope peptides based on conserved sequence analysis and B cell epitope prediction in HCV E2 region
Published in Immunologic research (01-02-2018)“…The high mutation rate of the hepatitis C virus (HCV) genome increases the genotype diversity and renders the detection of the virus more difficult. Therefore,…”
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A Binary Combinatorial Grammar for Chinese and Its Parsing Algorithm
Published in Sixth International Conference on Intelligent Systems Design and Applications (01-10-2006)“…In order to resolve the problem of low accuracy in Chinese natural language parsing introduced by the lack of complete grammar rules set, a binary…”
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Conference Proceeding -
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Sulfur and Oxygen Isotopes of Sulfate Extracted from Early Cambrian Phosphorite Nodules: Implications for Marine Redox Evolution in the Yangtze Platform
Published in Journal of earth science (Wuhan, China) (01-04-2016)“…Phosphorite nodule beds are discovered in the black shale of basal Niutitang Formation throughout the Yangtze Platform in South China, recording an important…”
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