Search Results - "Qiao, Xinyi"
-
1
Tumor-derived exosomal PD-L1: a new perspective in PD-1/PD-L1 therapy for lung cancer
Published in Frontiers in immunology (18-03-2024)“…Exosomes play a crucial role in facilitating intercellular communication within organisms. Emerging evidence indicates that a distinct variant of programmed…”
Get full text
Journal Article -
2
Exposure to 4-nonylphenol compromises Leydig cell development in pubertal male mice
Published in Ecotoxicology and environmental safety (01-11-2023)“…Exposure to 4-nonyl phenol (4-NP) on Leydig cell (LC) development and function remains poorly understood. We explored the effects of 4-NP on LC development and…”
Get full text
Journal Article -
3
Curcumin analogues exert potent inhibition on human and rat gonadal 3β-hydroxysteroid dehydrogenases as potential therapeutic agents: structure-activity relationship and in silico docking
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2023)“…Curcuminoids are functional food additives, and the effect on gonadal hormone biosynthesis remains unclear. Gonads contain 3β-hydroxysteroid dehydrogenase…”
Get full text
Journal Article -
4
Use of the prognostic nutrition index as a predictive biomarker in small-cell lung cancer patients undergoing immune checkpoint inhibitor treatment in the Chinese alpine region
Published in Frontiers in oncology (15-03-2023)“…Whether the prognostic nutritional index (PNI), which is suggested to reflect systemic inflammation and nutritional status of patients, could be used as an…”
Get full text
Journal Article -
5
Biomaterial-based strategy for bone tumor therapy and bone defect regeneration: An innovative application option
Published in Frontiers in materials (07-09-2022)“…Bone tumors are deadly and incurable diseases that invade large areas of bone, resulting in bone defects. Traditional therapies combining surgery,…”
Get full text
Journal Article -
6
Reassessing the Balanced Development of Compulsory Education
Published in Frontiers of Education in China (2012)“…The balanced development of compulsory education has been given due and lengthy coverage in the “Outline of China’s National Plan for Medium and Long-Term…”
Get full text
Journal Article -
7
Spectasterols, Aromatic Ergosterols with 6/6/6/5/5, 6/6/6/6, and 6/6/6/5 Ring Systems from Aspergillus spectabilis
Published in Journal of natural products (Washington, D.C.) (23-06-2023)“…Spectasterols A–E (1–5), aromatic ergosterols with unique ring systems, were isolated from Aspergillus spectabilis. Compounds 1 and 2 possess a 6/6/6/5/5 ring…”
Get full text
Journal Article -
8
Deoxynivalenol Inhibits Progenitor Leydig Cell Development by Stimulating Mitochondrial Fission in Rats
Published in Journal of agricultural and food chemistry (08-05-2024)“…Deoxynivalenol (DON) is a common food contaminant that can impair male reproductive function. This study investigated the effects and mechanisms of DON…”
Get full text
Journal Article -
9
Aculeatiols A–G: Lovastatin Derivatives Extracted from Aspergillus aculeatus
Published in Journal of natural products (Washington, D.C.) (26-04-2024)“…In this study, we isolated lovastatin derivatives, including aculeatiols A–G (1–7) and three known compounds (8–10), from Aspergillus aculeatus. Their…”
Get full text
Journal Article -
10
Chalcone derivatives from licorice inhibit human and rat gonadal 3β-hydroxysteroid dehydrogenases as therapeutic uses
Published in Journal of ethnopharmacology (05-12-2023)“…In traditional Chinese medicine, licorice (the roots of Glycyrrhiza glabra and G. inflata) has been used to treat inflammation and sexual debility for over…”
Get full text
Journal Article -
11
Carbon-chain length determines the binding affinity and inhibitory strength of per- and polyfluoroalkyl substances on human and rat steroid 5α-reductase 1 activity
Published in Chemico-biological interactions (01-05-2024)“…Per- and polyfluoroalkyl substances (PFAS) are widely used synthetic chemicals that persist in the environment and bioaccumulate in animals and humans. There…”
Get full text
Journal Article -
12
NL13, a novel curcumin analogue and polo like kinase 4 inhibitor, induces cell cycle arrest and apoptosis in prostate cancer models
Published in British journal of pharmacology (01-11-2024)“…Background and Purpose Prostate cancer remains a major public health burden worldwide. Polo like kinase 4 (PLK4) has emerged as a promising therapeutic target…”
Get full text
Journal Article -
13
Tetramethyl bisphenol A stimulates proliferation but inhibits fetal Leydig cell function in male rats by targeting estrogen receptor α after in utero exposure
Published in Environmental toxicology (01-11-2022)“…Tetramethyl bisphenol A (TMBPA) is a widely used flame retardant. TMBPA has been a toxic to Leydig cells in puberty, but it remains unclear whether TMBPA has a…”
Get full text
Journal Article -
14
Reassessing the Balanced Development of Compulsory Education
Published in Frontiers of education in China (01-06-2012)“…The balanced development of compulsory education has been given due and lengthy coverage in the “Outline of China’s National Plan for Medium and Long-Term…”
Get full text
Journal Article -
15
Softmax Regression Based on Bacterial Foraging Optimization Algorithm with t-Distribution Parameters
Published in 2021 IEEE 11th International Conference on Electronics Information and Emergency Communication (ICEIEC)2021 IEEE 11th International Conference on Electronics Information and Emergency Communication (ICEIEC) (01-01-2021)“…Softmax regression is a supervised multi-class nonlinear classification algorithm in machine learning. Sometimes it is also used in regression problems. It is…”
Get full text
Conference Proceeding -
16
Geological characteristics and shale gas distribution of carboniferous mudstones in the Tarim Basin,China
Published in Acta geochimica (01-06-2017)“…Extant research on Paleozoic mudstone is well developed in the Tarim Basin, while the research on Carboniferous mudstone is relatively weak. Through systematic…”
Get full text
Journal Article