Search Results - "Qiao, Shuo"

Update 2020: nomenclature and listing of celiac disease–relevant gluten epitopes recognized by CD4+ T cells by Sollid, Ludvig M., Tye-Din, Jason A., Qiao, Shuo-Wang, Anderson, Robert P., Gianfrani, Carmen, Koning, Frits

“…Celiac disease is caused by an abnormal intestinal T cell response to cereal gluten proteins. The disease has a strong human leukocyte antigen (HLA)…”
Get full text

Immunobiology and conflicting roles of the human CD161 receptor in T cells by Wyrożemski, Łukasz, Qiao, Shuo‐Wang

“…Human C‐type lectin‐like CD161 is a type‐II transmembrane protein expressed on the surface of various lymphocytes across innate and adaptive immune systems…”
Get full text

Stereotyped B‐cell responses are linked to IgG constant region polymorphisms in multiple sclerosis by Lindeman, Ida, Polak, Justyna, Qiao, Shuo‐Wang, Holmøy, Trygve, Høglund, Rune A., Vartdal, Frode, Berg‐Hansen, Pål, Sollid, Ludvig M., Lossius, Andreas

“…Clonally related B cells infiltrate the brain, meninges, and cerebrospinal fluid of MS patients, but the mechanisms driving the B‐cell response and shaping the…”
Get full text

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules by Sollid, Ludvig M., Qiao, Shuo-Wang, Anderson, Robert P., Gianfrani, Carmen, Koning, Frits

“…Celiac disease is caused by an abnormal intestinal T-cell response to gluten proteins of wheat, barley and rye. Over the last few years, a number of gluten…”
Get full text

Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics by Rath, Timo, Baker, Kristi, Dumont, Jennifer A, Peters, Robert T, Jiang, Haiyan, Qiao, Shuo-Wang, Lencer, Wayne I, Pierce, Glenn F, Blumberg, Richard S

“…Nearly 350 IgG-based therapeutics are approved for clinical use or are under development for many diseases lacking adequate treatment options. These include…”
Get more information

C‐type lectin‐like CD161 is not a co‐signalling receptor in gluten‐reactive CD4 + T cells by Wyrożemski, Łukasz, Sollid, Ludvig M., Qiao, Shuo‐Wang

“…C‐type lectin‐like CD161, a class II transmembrane protein, is a surface receptor expressed by NK cells and T cells. In coeliac disease, CD161 was expressed…”
Get full text

BraCeR: B-cell-receptor reconstruction and clonality inference from single-cell RNA-seq by Lindeman, Ida, Emerton, Guy, Mamanova, Lira, Snir, Omri, Polanski, Krzysztof, Qiao, Shuo-Wang, Sollid, Ludvig M., Teichmann, Sarah A., Stubbington, Michael J. T.

Get full text

Innate lymphoid cell characterization in the rat and their correlation to gut commensal microbes by Sudworth, Amanda, Segers, Filip M., Yilmaz, Bahtiyar, Guslund, Naomi C., Macpherson, Andrew J., Dissen, Erik, Qiao, Shuo‐Wang, Inngjerdingen, Marit

“…Innate lymphoid cells (ILCs) are important for tissue immune homeostasis, and are thoroughly characterized in mice and humans. Here, we have performed in‐depth…”
Get full text

Characterization of T‐cell receptor transgenic mice recognizing immunodominant HLA‐DQ2.5‐restricted gluten epitopes by Lindstad, Christian B., Qiao, Shuo‐Wang, Johannesen, Marie K., Fugger, Lars, Sollid, Ludvig M., du Pré, M. Fleur

“…We created a TCR transgenic mouse with CD4+ T cells recognizing the immunodominant DQ2.5‐glia‐ω2 gluten epitope. We show that these cells respond to deamidated…”
Get full text

Resident memory CD8 T cells persist for years in human small intestine by Bartolomé-Casado, Raquel, Landsverk, Ole J B, Chauhan, Sudhir Kumar, Richter, Lisa, Phung, Danh, Greiff, Victor, Risnes, Louise F, Yao, Ying, Neumann, Ralf S, Yaqub, Sheraz, Øyen, Ole, Horneland, Rune, Aandahl, Einar Martin, Paulsen, Vemund, Sollid, Ludvig M, Qiao, Shuo-Wang, Baekkevold, Espen S, Jahnsen, Frode L

“…Resident memory CD8 T (Trm) cells have been shown to provide effective protective responses in the small intestine (SI) in mice. A better understanding of the…”
Get full text

High-throughput sequencing of insect specimens with sub-optimal DNA preservation using a practical, plate-based Illumina-compatible Tn5 transposase library preparation method by Cobb, Lauren, de Muinck, Erik, Kollias, Spyros, Skage, Morten, Gilfillan, Gregor D, Sydenham, Markus A K, Qiao, Shuo-Wang, Star, Bastiaan

“…Entomological sampling and storage conditions often prioritise efficiency, practicality and conservation of morphological characteristics, and may therefore be…”
Get full text

Two novel HLA-DQ2.5-restricted gluten T cell epitopes in the DQ2.5-glia-γ4 epitope family by Qiao, Shuo-Wang, Sollid, Ludvig M.

“…Celiac disease is a chronic inflammatory condition of the small intestine caused by aberrant adaptive immune response to gluten protein from wheat and related…”
Get full text

HLA-DQ–Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption by Sarna, Vikas K., Lundin, Knut E.A., Mørkrid, Lars, Qiao, Shuo-Wang, Sollid, Ludvig M., Christophersen, Asbjørn

“…Celiac disease is characterized by HLA-DQ2/8-restricted responses of CD4+ T cells to cereal gluten proteins. A diagnosis of celiac disease based on serologic…”
Get full text

Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease by Risnes, Louise F, Christophersen, Asbjørn, Dahal-Koirala, Shiva, Neumann, Ralf S, Sandve, Geir K, Sarna, Vikas K, Lundin, Knut Ea, Qiao, Shuo-Wang, Sollid, Ludvig M

“…Little is known about the repertoire dynamics and persistence of pathogenic T cells in HLA-associated disorders. In celiac disease, a disorder with a strong…”
Get full text

A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease by Ting, Yi Tian, Dahal-Koirala, Shiva, Kim, Shi Keshia, Qiao, Shuo-Wang, Neumann, Ralf S., Lundin, Knut E. A., Petersen, Jan, Reid, Hugh H., Sollid, Ludvig M., Rossjohn, Jamie

“…The highly homologous human leukocyte antigen (HLA)-DQ2 molecules, HLA-DQ2.5 and HLA-DQ2.2, are implicated in the pathogenesis of celiac disease (CeD) by…”
Get full text

TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences by Dahal-Koirala, Shiva, Balaban, Gabriel, Neumann, Ralf Stefan, Scheffer, Lonneke, Lundin, Knut Erik Aslaksen, Greiff, Victor, Sollid, Ludvig Magne, Qiao, Shuo-Wang, Sandve, Geir Kjetil

“…Abstract T-cell receptor (TCR) sequencing has enabled the development of innovative diagnostic tests for cancers, autoimmune diseases and other applications…”
Get full text

CRISPR-Cas9/Cas12a-based genome editing in Atlantic cod (Gadus morhua) by López-Porras, Adrián, Berg, Ragnhild Stenberg, Burgerhout, Erik, Hansen, Øyvind J., Györkei, Ádám, Qiao, Shuo-Wang, Johansen, Finn-Eirik

“…Aquaculture is the fastest-growing food sector worldwide but faces sustainability challenges that need to be addressed in many ways, including genetic…”
Get full text

Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells by Lindeman, Ida, Zhou, Chunyan, Eggesbø, Linn M, Miao, Zhichao, Polak, Justyna, Lundin, Knut E A, Jahnsen, Jørgen, Qiao, Shuo-Wang, Iversen, Rasmus, Sollid, Ludvig M

“…Disease-specific plasma cells (PCs) reactive with transglutaminase 2 (TG2) or deamidated gluten peptides (DGPs) are abundant in celiac disease (CeD) gut…”
Get full text

Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq by Yao, Ying, Wyrozzemski, Lukasz, Lundin, Knut E. A, Sandve, Geir Kjetil, Qiao, Shuo-Wang

“…Gluten-specific CD4 + T cells drive the pathogenesis of celiac disease and circulating gluten-specific T cells can be identified by staining with HLA-DQ:gluten…”
Get full text

An FcRn-Dependent Role for Anti-flagellin Immunoglobulin G in Pathogenesis of Colitis in Mice by Kobayashi, Kanna, Qiao, Shuo–Wang, Yoshida, Masaru, Baker, Kristi, Lencer, Wayne I, Blumberg, Richard S

“…Background & Aims The neonatal Fc receptor for immunoglobulin (Ig)G (FcRn) protects monomeric IgG from catabolism in parenchymal and hematopoietic cells during…”
Get full text