Search Results - "Qiang, Huiping"
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New advances in antiangiogenic combination therapeutic strategies for advanced non-small cell lung cancer
Published in Journal of cancer research and clinical oncology (01-03-2020)“…Purpose Tumor growth relies on the sufficient blood supply and continuously requires new blood vessels to maintain, which lead to vascular abnormalities…”
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467 A real-world retrospective study of immunotherapy in NSCLC patients with KRAS mutation
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundKRAS mutations occur in about 15–20% of patients with lung cancer. Due to the small size and smooth surface of KRAS protein, it is difficult to…”
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Mining GEO and TCGA Database for Immune Microenvironment of Lung Squamous Cell Carcinoma Patients With or Without Chemotherapy
Published in Frontiers in oncology (08-02-2022)“…Chemotherapy is the main treatment for patients with lung squamous cell carcinoma (LUSC). However, how chemotherapy affects their immune system is rarely…”
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Effective low-dose Anlotinib induces long-term tumor vascular normalization and improves anti-PD-1 therapy
Published in Frontiers in immunology (03-08-2022)“…Anlotinib is a new multitarget tyrosine kinase inhibitor for tumor angiogenesis, and its monotherapy exhibits a decent clinical efficacy. However, the process…”
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Comparison of the efficacy and safety in the treatment strategies between chemotherapy combined with antiangiogenic and with immune checkpoint inhibitors in advanced non-small cell lung cancer patients with negative PD-L1 expression: A network meta-analysis
Published in Frontiers in oncology (29-11-2022)“…In the first-line treatment of advanced non-small cell lung cancer (NSCLC), for those patients with negative PD-L1 expression, which treatment strategy has the…”
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Anti-angiogenic therapy or immunotherapy? A real-world study of patients with advanced non-small cell lung cancer with EGFR/HER2 exon 20 insertion mutations
Published in Frontiers in oncology (19-03-2024)“…For patients with EGFR/HER2 exon20 insertions, platinum-containing double-drug chemotherapy is still the standard treatment method. First-generation TKIs have…”
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Epidermal Growth Factor Receptor Mutation Status and Response to Tyrosine Kinase Inhibitors in Advanced Chinese Female Lung Squamous Cell Carcinoma: A Retrospective Study
Published in Frontiers in oncology (02-04-2021)“…The frequency of epidermal growth factor receptor (EGFR) mutations and the efficacy of tyrosine kinase inhibitor (TKI) in Chinese female patients with lung…”
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Dynamic alterations of ctDNA associate with the therapeutic outcome in the advanced non‐small cell lung cancer patients who received sintilimab plus anlotinib regime as 1st line therapy
Published in Clinical and translational medicine (01-06-2023)“…[...]we attempted to analyse the association between bTMB and progression-free survival (PFS)/overall survival (OS). [...]we evaluated the predictive value of…”
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Phase 1b Study of Sintilimab Plus Anlotinib as First-line Therapy in Patients With Advanced NSCLC
Published in Journal of thoracic oncology (01-04-2021)“…Although the interaction between tumor immune microenvironment and angiogenesis has been well established, evidence supporting the chemo-free combination of…”
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Impact of PD-L1 expression on the efficacy of first-line crizotinib in advanced ROS1-rearranged NSCLC
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2024)“…•The predictive accuracy of PD-L1 expression in NSCLC patients with oncogenic drivers, such as those receiving TKI treatment, remains controversial.•We…”
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Atorvastatin suppressed proliferation and facilitated apoptosis of A549 cells through mediating recruitment of Fas and CD59 in lipid raft
Published in Tropical journal of pharmaceutical research (01-02-2022)“…Purpose: Lipid raft facilitated progression of NSCLC and atorvastatin could break cholesterol. The purpose of this study was to determine the potential…”
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Special issue “The advance of solid tumor research in China”: Real‐world clinical outcomes of alectinib for advanced nonsmall‐cell lung cancer patients with ALK fusion in China
Published in International journal of cancer (01-01-2023)“…Global phase 3 trials have demonstrated the priority of several next‐generation anaplastic lymphoma kinase‐tyrosine kinase inhibitors (ALK‐TKIs). However,…”
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Clinical characteristics and prognostic factors of surgically resected combined small cell lung cancer: a retrospective study
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2020)“…•SCLC/LCNEC was the most common type of C-SCLC.•SCLC/LCNEC patients' DFS and OS were also longer than other combined types.•Adjuvant chemotherapy of EP/EC…”
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Treatment efficacy of HER2-mutant lung adenocarcinoma by immune checkpoint inhibitors: a multicenter retrospective study
Published in Cancer Immunology, Immunotherapy (01-07-2022)“…Background Despite the remarkable clinical advance of immune checkpoint inhibitors (ICIs) in the treatment of lung cancer, there are limited studies focused on…”
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Neoadjuvant immunology therapy in patients with non-small cell lung cancer and chronic obstructive pulmonary disease
Published in Journal of thoracic disease (01-01-2023)Get full text
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EGFR Tyrosine Kinase Inhibitor (TKI) Combined With Concurrent or Sequential Chemotherapy for Patients With Advanced Lung Cancer and Gradual Progression After First-Line EGFR-TKI Therapy: A Randomized Controlled Study
Published in Clinical lung cancer (01-05-2021)“…Continuing tyrosine kinase inhibitor (TKI) therapy may be beneficial when patients with non–small-cell lung cancer and EGFR mutations experience gradual…”
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Anlotinib Combined with Anti‐PD1 Potentiates Anti‐Tumor Immunity via Immunogenic Cell Death and Macrophage Reprogramming
Published in Advanced therapeutics (01-11-2023)“…The combination therapy of targeted drugs and immune checkpoint inhibitors has shown prominent success. In addition to blocking mutated oncogene downstream…”
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Special issue "The advance of solid tumor research in China": Real-world clinical outcomes of alectinib for advanced non-small-cell lung cancer patients with ALK fusion in China
Published in International journal of cancer (17-05-2022)“…Global phase 3 trials have demonstrated the priority of several next-generation anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs). However,…”
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