Search Results - "Qiang, Fulin"
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A functional polymorphism in TFF1 promoter is associated with the risk and prognosis of gastric cancer
Published in International journal of cancer (01-05-2018)“…Trefoil Factor 1 (TFF1, also named pS2), which serves as the gastrointestinal mucosal protector, is known as gastric‐specific tumor suppressor gene. However,…”
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Genome-wide long non-coding RNAs identified a panel of novel plasma biomarkers for gastric cancer diagnosis
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-07-2019)“…Background Although long non-coding RNAs (lncRNAs) are regarded as useful plasma-based biomarkers for cancer detection, the potential diagnostic value of…”
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KCNMA1 cooperating with PTK2 is a novel tumor suppressor in gastric cancer and is associated with disease outcome
Published in Molecular cancer (23-02-2017)“…Inactivation of tumor suppressor genes by promoter hypermethylation plays a key role in the tumorgenesis. It is necessary to uncover the detailed pattern of…”
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Prognostic and Predictive Role of JWA and XRCC1 Expressions in Gastric Cancer
Published in Clinical cancer research (15-05-2012)“…To investigate the expression pattern and significance of DNA repair genes JWA and X-ray repair cross complement group 1 (XRCC1) in gastric cancer. Expressions…”
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Circulating MicroRNA-26a in Plasma and Its Potential Diagnostic Value in Gastric Cancer
Published in PloS one (24-03-2016)“…In the past decades, a good deal of studies has provided the possibility of the circulating microRNAs (miRNAs) as noninvasive biomarkers for cancer diagnosis…”
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JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancer
Published in Carcinogenesis (New York) (01-02-2014)“…JWA, a multifunctional microtubule-binding protein, plays an important role in regulating tumor metastasis via inhibition of matrix metalloproteinase-2…”
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A Genetic Variant Located in miR-146b Promoter Region Is Associated with Prognosis of Gastric Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-07-2018)“…SNPs in the promoter region of miRNAs have been reported to be associated with cancer prognosis. Our previous study found that miR-146b had a strong…”
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The opposite prognostic significance of nuclear and cytoplasmic p21 expression in resectable gastric cancer patients
Published in Journal of gastroenterology (01-11-2014)“…Background Protein p21 Cip1/Waf1 is a cyclin-dependent kinase inhibitor, which plays important roles in cell cycle arrest, senescence, and apoptosis…”
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SMADs binding site polymorphisms rs9911630 is associated with susceptibility but not prognosis of gastric cancer: a case control study
Published in Journal of Cancer (01-01-2020)“…Background: Single nucleotide polymorphisms (SNPs) in transcription factor binding sites (TFBS) can change their binding strength, affecting the function of…”
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PSMB4 expression associates with epithelial ovarian cancer growth and poor prognosis
Published in Archives of gynecology and obstetrics (01-06-2016)“…Purpose In this study, we investigated the expression and role of PSMB4 in human epithelial ovarian cancer(EOC). Methods Western blot was used to evaluate the…”
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MDM2 is a useful prognostic biomarker for resectable gastric cancer
Published in Cancer science (01-05-2013)“…Expression of MDM2 protein appears to be increased in malignancy and correlated to prognosis of tumors, but its role in gastric cancer remains controversial…”
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CTLA-4 gene polymorphism +49 A/G contributes to genetic susceptibility to two infection-related cancers—hepatocellular carcinoma and cervical cancer
Published in Human immunology (01-09-2010)“…Abstract Accumulated evidence suggested that cytotoxic T-lymphocyte antigen 4 (CTLA4) plays an important role in the negative regulation of T-cell…”
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Synergistic role between p53 and JWA: prognostic and predictive biomarkers in gastric cancer
Published in PloS one (21-12-2012)“…Expression of p53 appears to be correlated to prognosis in patients with malignancy, but its role in gastric carcinoma has remained controversial. Recently we…”
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High FAK combined with low JWA expression: clinical prognostic and predictive role for adjuvant fluorouracil–leucovorin–oxaliplatin treatment in resectable gastric cancer patients
Published in Journal of gastroenterology (01-09-2013)“…Background The multifunctional protein JWA was previously identified as a novel regulator of focal adhesion kinase (FAK/PTK2) in suppressing cancer cell…”
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Circulating IL-1β levels, polymorphisms of IL-1B, and risk of cervical cancer in Chinese women
Published in Journal of cancer research and clinical oncology (01-05-2010)“…Purpose Long-term human papillomavirus (HPV) infection is a prerequisite for cervical cancer. IL-1β and IL-1Ra expression levels play an important role in…”
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Dynamic contrast-enhanced MRI versus 18F-FDG PET/CT: Which is better in differentiation between malignant and benign solitary pulmonary nodules?
Published in Chinese journal of cancer research (01-02-2018)“…OBJECTIVETo prospectively compare the discriminative capacity of dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) with that of…”
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The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population
Published in Oncotarget (13-10-2015)“…The HOX transcript antisense intergenic RNA (HOTAIR), a well-known long noncoding RNA, is involved in pathogenesis and progress of multiple tumors. Its ectopic…”
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miR-107 regulates tumor progression by targeting NF1 in gastric cancer
Published in Scientific reports (09-11-2016)“…Our previous genome-wide miRNA microarray study revealed that miR-107 was upregulated in gastric cancer (GC). In this study we aimed to explore its biological…”
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CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer
Published in Gut (01-04-2013)“…CHIP (carboxy terminus of Hsc70 interacting protein) is an E3 ubiquitin ligase that can induce ubiquitination and degradation of several tumour related…”
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