Search Results - "Qian, Ziliang"
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Translating the Therapeutic Potential of AZD4547 in FGFR1-Amplified Non―Small Cell Lung Cancer through the Use of Patient-Derived Tumor Xenograft Models
Published in Clinical cancer research (15-12-2012)“…To investigate the incidence of FGFR1 amplification in Chinese non-small cell lung cancer (NSCLC) and to preclinically test the hypothesis that the novel,…”
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2
Combination treatment for advanced hepatocellular carcinoma with portal vein tumour thrombus: A case report
Published in Journal of international medical research (01-02-2021)“…We present a case of a 43-year-old man with advanced hepatocellular carcinoma (HCC) with portal vein tumour thrombus. Initially, transcatheter arterial…”
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3
Seven Genes Associated With Lymphatic Metastasis in Thyroid Cancer That Is Linked to Tumor Immune Cell Infiltration
Published in Frontiers in oncology (24-01-2022)“…Since there are few studies exploring genes associated with lymphatic metastasis of thyroid carcinoma (THCA), this study was conducted to explore genes…”
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4
Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma
Published in PloS one (22-04-2015)“…To gain molecular insights of HBV integration that may contribute to HCC tumorigenesis, we performed whole transcriptome sequencing and whole genome copy…”
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Investigating Acupoint Selection and Combinations of Acupuncture for Tic Disorders: An Association Rule Mining and Network Analysis Study
Published in Frontiers in neurology (10-06-2022)“…Objective Tic disorders (TDs) are common mental disorders in children and adolescents, and the clinical application of acupuncture for treating TDs is becoming…”
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Genome-wide chromosomal instability by cell-free DNA sequencing predicts survival in patients with metastatic breast cancer
Published in Breast (Edinburgh) (01-10-2020)“…Genome-wide chromosomal instability, instead of specific somatic mutations or copy-number alterations in selected genes, is a significant property of cancer…”
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A Novel Set of DNA Methylation Markers in Urine Sediments for Sensitive/Specific Detection of Bladder Cancer
Published in Clinical cancer research (15-12-2007)“…Purpose: This study aims to provide a better set of DNA methylation markers in urine sediments for sensitive and specific detection of bladder cancer…”
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Whole genome gene copy number profiling of gastric cancer identifies PAK1 and KRAS gene amplification as therapy targets
Published in Genes chromosomes & cancer (01-11-2014)“…Gastric cancer is the second leading cause of death from cancer worldwide, with an approximately 20% 5‐year survival rate. To identify molecular subtypes…”
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Copy number variation of urine exfoliated cells by low-coverage whole genome sequencing for diagnosis of prostate adenocarcinoma: a prospective cohort study
Published in BMC medical genomics (05-05-2022)“…Non-invasive, especially the urine-based diagnosis of prostate cancer (PCa) remains challenging. Although prostate cancer antigen (PSA) is widely used in…”
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10
Virtual screening combined with experimental verification reveals the potential mechanism of Fuzitang decoction against Gouty Arthritis
Published in Heliyon (01-12-2023)“…and Purpose: Fuzitang decoction (FZT), a classic prescription of traditional Chinese medicine (TCM), has excellent efficacy in treating gouty arthritis (GA)…”
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Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma
Published in Oncotarget (02-02-2016)“…Hepatocellular carcinoma (HCC) is the fifth most common type of cancers worldwide. However, current therapeutic approaches for this epidemic disease are…”
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High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer
Published in Breast cancer (Tokyo, Japan) (01-01-2022)“…Background Though BRCA1 mutation is the most susceptible factor of breast cancer, its prognostic value is disputable. Here in this study, we use a novel method…”
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Cell-free DNA chromosome copy number variations predict outcomes in plasma cell myeloma
Published in Blood cancer journal (New York) (05-09-2023)Get full text
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14
Washout DNA copy number analysis by low-coverage whole genome sequencing for assessment of thyroid FNAs
Published in Frontiers in endocrinology (Lausanne) (14-10-2022)“…Background Papillary thyroid microcarcinoma (PTMC) is defined as a papillary carcinoma measuring ≤ 10 mm. The current management of PTMC has become more…”
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Recurrent amplification of MYC and TNFRSF11B in 8q24 is associated with poor survival in patients with gastric cancer
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-01-2016)“…Background Gastric cancer (GC) is an aggressive malignancy whose mechanisms of development and progression are poorly understood. The identification of…”
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Investigation of Plasma cell‐free cancer genome chromosomal instability as a tool for targeted minimally invasive biomarkers for primary liver cancer diagnoses
Published in Cancer medicine (Malden, MA) (01-07-2020)“…Purpose To characterize plasma cell‐free cancer genome chromosomal instabilities (CIN) in patients with liver cancer and to evaluate the potential of CIN as…”
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The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
Published in BMC bioinformatics (16-06-2008)“…Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation…”
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Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis
Published in Science signaling (06-11-2012)“…Enhanced activation of phosphoinositide 3-kinase (PI3K) is a hallmark of many human tumors because it promotes cell proliferation and survival through several…”
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The use of global transcriptional analysis to reveal the biological and cellular events involved in distinct development phases of Trichophyton rubrum conidial germination
Published in BMC genomics (11-04-2007)“…Conidia are considered to be the primary cause of infections by Trichophyton rubrum. We have developed a cDNA microarray containing 10250 ESTs to monitor the…”
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Using GeneReg to construct time delay gene regulatory networks
Published in BMC research notes (25-05-2010)“…Understanding gene expression and regulation is essential for understanding biological mechanisms. Because gene expression profiling has been widely used in…”
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