Search Results - "Qian, Zhiyong"
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Review of a new bone tumor therapy strategy based on bifunctional biomaterials
Published in Bone Research (16-03-2021)“…Bone tumors, especially those in osteosarcoma, usually occur in adolescents. The standard clinical treatment includes chemotherapy, surgical therapy, and…”
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Recent progress in targeted delivery vectors based on biomimetic nanoparticles
Published in Signal transduction and targeted therapy (07-06-2021)“…Over the past decades, great interest has been given to biomimetic nanoparticles (BNPs) since the rise of targeted drug delivery systems and biomimetic…”
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ROS‐Responsive Camptothecin Prodrug Nanoparticles for On‐Demand Drug Release and Combination of Chemotherapy and Photodynamic Therapy
Published in Advanced functional materials (01-12-2020)“…Minimizing drug leakage in systemic circulation, synchronizing the in vivo fate of multiple drugs, and precisely controlling tumor locoregional drug release,…”
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Gold nanorods and nanohydroxyapatite hybrid hydrogel for preventing bone tumor recurrence via postoperative photothermal therapy and bone regeneration promotion
Published in Bioactive materials (01-08-2021)“…Osteosarcoma is a malignant bone tumor, which often occurs in adolescents. However, surgical resection usually fails to completely remove the tumor clinically,…”
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Tumor Microenvironment Responsive Drug‐Dye‐Peptide Nanoassembly for Enhanced Tumor‐Targeting, Penetration, and Photo‐Chemo‐Immunotherapy
Published in Advanced functional materials (09-05-2019)“…Nanomedicine constructed by therapeutics has unique and irreplaceable advantages in biomedical applications, especially in drug delivery for cancer therapy…”
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Intratumoral fate of functional nanoparticles in response to microenvironment factor: Implications on cancer diagnosis and therapy
Published in Advanced drug delivery reviews (15-03-2019)“…The extraordinary growth and progression of tumor require enormous nutrient and energy. Unregulated behaviors of cancer cell progressing and persistently…”
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GMSC-Derived Exosomes Combined with a Chitosan/Silk Hydrogel Sponge Accelerates Wound Healing in a Diabetic Rat Skin Defect Model
Published in Frontiers in physiology (07-11-2017)“…Delayed wound healing in diabetic patients is one of the most challenging complications in clinical medicine, as it poses a greater risk of gangrene,…”
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Feasibility and cardiac synchrony of permanent left bundle branch pacing through the interventricular septum
Published in Europace (London, England) (01-11-2019)“…Abstract Aims Left bundle branch pacing (LBBP) recently emerges as a novel pacing modality. We aimed to evaluate the feasibility and cardiac synchrony of…”
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A review on recent advances in hydrogen peroxide electrochemical sensors for applications in cell detection
Published in Chinese chemical letters (01-09-2022)“…Hydrogen peroxide (H2O2) is a very simple bioactive small molecule. In living organisms, H2O2 plays an important role in intracellular signaling. It is…”
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10
Current research progress of photopolymerized hydrogels in tissue engineering
Published in Chinese chemical letters (01-07-2021)“…The review article summarizes the applications of photopolymerized hydrogels in tissue engineering. In this article, we discussed the types and advantages of…”
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Biodegradable CSMA/PECA/Graphene Porous Hybrid Scaffold for Cartilage Tissue Engineering
Published in Scientific reports (11-05-2015)“…Owing to the limited repair capacity of articular cartilage, it is essential to develop tissue-engineered cartilage for patients suffering from joint disease…”
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Sustained co-delivery of gemcitabine and cis-platinum via biodegradable thermo-sensitive hydrogel for synergistic combination therapy of pancreatic cancer
Published in Nano research (01-06-2019)“…Pancreatic cancer is one of the most devastating cancers with poor prognosis and no significant change in the survival rate over the past decades. Localized…”
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Polymeric Nanoparticles with ROS‐Responsive Prodrug and Platinum Nanozyme for Enhanced Chemophotodynamic Therapy of Colon Cancer
Published in Advanced science (01-10-2020)“…The combination of chemotherapy and photodynamic therapy (PDT) has promising potential in the synergistic treatment of cancer. However, chemotherapy and…”
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14
Cationic nanocarriers induce cell necrosis through impairment of Na^+/K^+-ATPase and cause subsequent inflammatory response
Published in Cell research (01-02-2015)“…Nanocarriers with positive surface charges are known for their toxicity which has limited their clinical appli- cations. The mechanism underlying their…”
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Sustained and targeted delivery of siRNA/DP7‐C nanoparticles from injectable thermosensitive hydrogel for hepatocellular carcinoma therapy
Published in Cancer science (01-06-2021)“…Hepatocellular carcinoma (HCC) is one of the most lethal cancers in humans. The inhibition of peptidyl‐prolyl cis/trans isomerase (Pin1) gene expression may…”
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An injectable photopolymerized hydrogel with antimicrobial and biocompatible properties for infected skin regeneration
Published in NPG Asia materials (2020)“…Currently, wound infection is an important health problem for the public. Wound infection can not only hinder healing but it can also lead to serious…”
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17
Surface Modification of Dental Titanium Implant by Layer-by-Layer Electrostatic Self-Assembly
Published in Frontiers in physiology (07-08-2017)“…implants that are composed of titanium and titanium alloys as raw materials are widely used in the fields of biology and medicine. In the field of dental…”
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Novel Approach of Using Near-Infrared Responsive PEGylated Gold Nanorod Coated Poly(l‑lactide) Microneedles to Enhance the Antitumor Efficiency of Docetaxel-Loaded MPEG-PDLLA Micelles for Treating an A431 Tumor
Published in ACS applied materials & interfaces (10-05-2017)“…The combination of chemotherapy and photothermal therapy (PTT) plays a significant role in synergistic tumor therapy. However, a high dosage of chemotherapy…”
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Physical-, chemical-, and biological-responsive nanomedicine for cancer therapy
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-01-2020)“…Cancer therapy is unsatisfactory as it typically has serious side effects, because normal cells in healthy organs are destroyed along with the tumor. Thus,…”
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Engineering Nanoparticles for Targeted Delivery of Nucleic Acid Therapeutics in Tumor
Published in Molecular therapy. Methods & clinical development (15-03-2019)“…In the past 10 years, with the increase of investment in clinical nano-gene therapy, there are many trials that have been discontinued due to poor efficacy and…”
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