Search Results - "Qian, Zhaoqiang"
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High salt diet impairs memory‐related synaptic plasticity via increased oxidative stress and suppressed synaptic protein expression
Published in Molecular nutrition & food research (01-10-2017)“…Scope A high salt (HS) diet is detrimental to cognitive function, in addition to having a role in cardiovascular disorders. However, the method by which an HS…”
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2
Involvement of Midbrain Dopamine Neuron Activity in Negative Reinforcement Learning in Mice
Published in Molecular neurobiology (01-11-2021)“…The activity of the midbrain dopamine system reflects the valence of environmental events and modulates various brain structures to modify an organism’s…”
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Correction to: Involvement of Midbrain Dopamine Neuron Activity in Negative Reinforcement Learning in Mice
Published in Molecular neurobiology (01-12-2021)Get full text
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4
Transcriptional and splicing dysregulation in the prefrontal cortex in valproic acid rat model of autism
Published in Reproductive toxicology (Elmsford, N.Y.) (01-04-2018)“…•Acute postnatal exposure to VPA induced autism-like behaviors.•VPA could affect transcriptional and splicing events genome-wide.•Dysregulated genes are…”
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Altered expression of glycan patterns and glycan-related genes in the medial prefrontal cortex of the valproic acid rat model of autism
Published in Frontiers in cellular neuroscience (08-12-2022)“…Autism spectrum disorders (ASD) represent a group of neurodevelopmental defects characterized by social deficits and repetitive behaviors. Alteration in…”
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6
Cannabinoid-Elicited Conditioned Place Preference in a Modified Behavioral Paradigm
Published in Biological & pharmaceutical bulletin (01-05-2016)“…Cannabinoids are the active ingredients in marijuana, which is among the most widely used addictive drugs despite the well-documented harmfulness related to…”
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RNA-Seq data on prefrontal cortex in valproic acid model of autism and control rats
Published in Data in brief (01-06-2018)“…The transcriptome sequencing data of valproic acid (VPA) model of autism and control rats are presented. VPA model of autism was induced by a single…”
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Downregulation of mGluR2/3 receptors during morphine withdrawal in rats impairs mGluR2/3- and NMDA receptor-dependent long-term depression in the nucleus accumbens
Published in Neuroscience letters (18-01-2019)“…•Low-frequency stimulation of the prefrontal cortex induces a long-term depression at synapses of the nucleus accumbens in naïve rats.•The long-term depression…”
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The Endocannabinoid System Contributes to Memory Deficits Induced by Rapid-eye-movement Sleep Deprivation in Adolescent Mice
Published in Neuroscience (01-05-2020)“…•NESS0327 rescued the memory deficit induced by REMSD in adolescent mice.•REMSD impaired the eCB-related synaptic plasticity in CA1.•REMSD downregulated the…”
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N 6 -methyladenosine RNA modification of glutamatergic neurons is associated with contextual fear discrimination
Published in Physiology & behavior (01-05-2022)“…Fear memory overgeneralization is a hallmark of many stress-related disorders, especially posttraumatic stress disorder. The neurobiology of fear memory…”
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Activation of CB1 receptors on GABAergic interneurons in the ventrolateral orbital cortex induces analgesia
Published in Neuroscience letters (25-09-2020)“…•HU210 activates the VLO in nerve injured mice.•Nerve injury up-regulates CB1 receptors in the VLO.•Microinjection of HU210 in the VLO produces analgesia.•CB1…”
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N6-methyladenosine RNA modification of glutamatergic neurons is associated with contextual fear discrimination
Published in Physiology & behavior (01-05-2022)“…•The hippocampal m6A methylation abundance is positively associated with accurate threat discrimination ability.•The methyltransferase Mettl3 levels also…”
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Abnormal reinforcement learning in a mice model of autism induced by prenatal exposure to valproic acid
Published in Behavioural brain research (01-10-2020)“…Individuals with autism spectrum disorder (ASD) display dysfunction in learning from environmental stimulus that have positive or negative emotional values,…”
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Loss of control over mild aversive events produces significant helplessness in mice
Published in Behavioural brain research (30-12-2019)“…Most of the pathophysiology of depression are still unknown because of its numerous disease states of distinct etiology and pathogenesis. Stressful rodent…”
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5-HT1A autoreceptor in dorsal raphe nucleus mediates sensitization of conditioned place preference to cocaine in mice experienced with chronic pain
Published in Neuroreport (12-06-2019)“…Chronic stress, including chronic neuropathic pain, cannot only induce depressive disorders but also enhance sensitization to addictive drugs. Ample evidence…”
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Cannabinoids-induced peripheral analgesia depends on activation of BK channels
Published in Brain research (15-05-2019)“…•Activation of CB1 receptors on injured axon inhibits ectopic firing.•Blocking BK channels reverses the firing-suppressing effect of cannabinoids.•Blocking BK…”
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Stress Controllability Modulates Basal Activity of Dopamine Neurons in the Substantia Nigra Compacta
Published in eNeuro (01-05-2021)“…Prolonged stress induces neural maladaptations in the mesolimbic dopamine (DA) system and produces emotional and behavioral disorders. However, the effects of…”
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