Search Results - "Qian, Wei Ping"
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Cyclins regulating oocyte meiotic cell cycle progression
Published in Biology of reproduction (21-11-2019)“…Oocyte meiotic maturation is a vital and final process in oogenesis. Unlike somatic cells, the oocyte needs to undergo two continuous meiotic divisions…”
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Transient inhibition of CDK2 activity prevents oocyte meiosis I completion and egg activation in mouse
Published in Journal of cellular physiology (01-11-2022)“…Mammalian oocytes are arrested at the diplotene stage of prophase I during fetal or postnatal development. It was reported that cyclin‐dependent kinases (CDK1)…”
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3
Overexpression of cyclin A1 promotes meiotic resumption but induces premature chromosome separation in mouse oocyte
Published in Journal of cellular physiology (01-10-2020)“…Mammalian cyclin A1 is prominently expressed in testis and essential for meiosis in the male mouse, however, it shows weak expression in ovary, especially…”
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4
CDC6 regulates both G2/M transition and metaphase‐to‐anaphase transition during the first meiosis of mouse oocytes
Published in Journal of cellular physiology (01-07-2020)“…Cell division cycle protein, CDC6, is essential for the initiation of DNA replication. CDC6 was recently shown to inhibit the microtubule‐organizing activity…”
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5
An endometrial receptivity scoring system basing on the endometrial thickness, volume, echo, peristalsis, and blood flow evaluated by ultrasonography
Published in Frontiers in endocrinology (Lausanne) (09-08-2022)“…Background Establishing a successful pregnancy depends on the endometrium and the embryo. It is estimated that suboptimal endometrial receptivity account for…”
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Specific deletion of protein phosphatase 6 catalytic subunit in Sertoli cells leads to disruption of spermatogenesis
Published in Cell death & disease (27-09-2021)“…Protein phosphatase 6 (PP6) is a member of the PP2A-like subfamily, which plays significant roles in numerous fundamental biological activities. We found that…”
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SRSF2 is required for mRNA splicing during spermatogenesis
Published in BMC biology (23-10-2023)“…Abstract Background RNA splicing plays significant roles in fundamental biological activities. However, our knowledge about the roles of alternative splicing…”
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8
Effectiveness of non-invasive chromosomal screening for normal karyotype and chromosomal rearrangements
Published in Frontiers in genetics (13-03-2023)“…To study the accuracy of non-invasive chromosomal screening (NICS) results, in normal chromosomes and chromosomal rearrangement groups and to investigate…”
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IL-7 Induces Bone Loss in vivo by Induction of Receptor Activator of Nuclear Factor κB Ligand and Tumor Necrosis Factor α from T Cells
Published in Proceedings of the National Academy of Sciences - PNAS (07-01-2003)“…IL-7, a powerful lymphopoietic cytokine, is elevated in rheumatoid arthritis (RA) and known to induce bone loss when administered in vivo. IL-7 has been…”
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The Cyclin B2/CDK1 Complex Conservatively Inhibits Separase Activity in Oocyte Meiosis II
Published in Frontiers in cell and developmental biology (11-03-2021)“…Recently, we have reported that the cyclin B2/CDK1 complex regulates homologous chromosome segregation through inhibiting separase activity in oocyte meiosis…”
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Critical Functions of PP2A-Like Protein Phosphotases in Regulating Meiotic Progression
Published in Frontiers in cell and developmental biology (25-02-2021)“…Meiosis is essential to the continuity of life in sexually-reproducing organisms through the formation of haploid gametes. Unlike somatic cells, the germ cells…”
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Deletion of Ck2β gene causes germ cell development arrest and azoospermia in male mice
Published in Cell proliferation (01-01-2020)“…Objectives In humans, non‐obstructive azoospermia (NOA) is a major cause of male infertility. However, the aetiology of NOA is largely unknown. Previous…”
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The effect of oral vitamin E supplementation on infertile women: a systematic review and meta-analysis
Published in Clinical and experimental obstetrics & gynecology (15-04-2021)“…This study was aimed to investigate the effect of vitamin E (Vit E) supplementation on endometrial thickness and pregnancy outcomes in infertile women. The…”
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Cell Division Cycle 5-Like Regulates Metaphase-to-Anaphase Transition in Meiotic Oocyte
Published in Frontiers in cell and developmental biology (01-07-2021)“…The quality of oocytes is a vital factor for embryo development. Meiotic progression through metaphase I usually takes a relatively long time to ensure correct…”
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Treatment of Infertile Women with Unilateral Tubal Occlusion Diagnosed by Hysterosalpingography: The Role of Intrauterine Insemination
Published in Current medical science (01-08-2020)“…Summary The optimal assisted reproductive treatment strategy for infertile women with unilateral tubal obstruction remains uncertain. To investigate the role…”
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16
Estrogen Prevents Bone Loss through Transforming Growth Factor β Signaling in T Cells
Published in Proceedings of the National Academy of Sciences - PNAS (23-11-2004)“…Estrogen (E) deficiency leads to an expansion of the pool of tumor necrosis factor (TNF)-producing T cells through an IFN-γ-dependent pathway that results in…”
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An IL-7-Dependent Rebound in Thymic T Cell Output Contributes to the Bone Loss Induced by Estrogen Deficiency
Published in Proceedings of the National Academy of Sciences - PNAS (15-11-2005)“…The bone wasting induced by estrogen deficiency is, in part, a consequence of increased T cell production of the osteoclastogenic cytokine TNF-α. This…”
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Post-ovulatory aging of mouse oocytes in vivo and in vitro: Effects of caffeine on exocytosis and translocation of cortical granules
Published in Animal science journal (01-11-2016)“…The developmental potential of post‐ovulatory oocytes decreases with aging in vivo and in vitro. In this study, we aimed to investigate the effects of a potent…”
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19
Evaluation of the Genetic Variation Spectrum Related to Corneal Dystrophy in a Large Cohort
Published in Frontiers in cell and developmental biology (18-03-2021)“…To characterize the genetic landscape and mutation spectrum of patients with corneal dystrophies (CDs) in a large Han ethnic Chinese Cohort with inherited eye…”
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The cyclin B2/CDK1 complex inhibits separase activity in mouse oocyte meiosis I
Published in Development (Cambridge) (01-12-2019)“…ABSTRACT Chromosome segregation is driven by separase, activity of which is inhibited by binding to securin and cyclin B1/CDK1. In meiosis, premature separase…”
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