Search Results - "Qian, Qiuhui"
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Carrier‐Free Delivery of Precise Drug–Chemogene Conjugates for Synergistic Treatment of Drug‐Resistant Cancer
Published in Angewandte Chemie International Edition (05-10-2020)“…Combinatorial antitumor therapies using different combinations of drugs and genes are emerging as promising ways to overcome drug resistance, which is a major…”
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Ferroptosis Promotes Photodynamic Therapy: Supramolecular Photosensitizer-Inducer Nanodrug for Enhanced Cancer Treatment
Published in Theranostics (2019)“…The noninvasive nature of photodynamic therapy (PDT) enables the preservation of organ function in cancer patients. However, PDT is impeded by hypoxia in the…”
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Induction of lipid metabolism dysfunction, oxidative stress and inflammation response by tris(1-chloro-2-propyl)phosphate in larval/adult zebrafish
Published in Environment international (01-02-2022)“…[Display omitted] •Acute and chronic TCPP exposure caused excess lipid accumulation in zebrafish.•TCPP exposure promoted adipogenesis and suppressed fatty…”
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Analysis of key circRNA events in the AOP framework of TCS acting on zebrafish based on the data-driven
Published in Ecotoxicology and environmental safety (15-07-2024)“…Triclosan (TCS) is a broad-spectrum antibiotic widely used in various personal care products. Research has found that exposure to TCS can cause toxic effects…”
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Preparation of Electrochemical Cytosensor for Sensitive Detection of HeLa Cells Based on Self-Assembled Monolayer
Published in Electrochimica acta (20-03-2014)“…It is highly desirable to develop simple and rapid method to detect cancer cells. In this case, a simple method for electrochemical detecting cell numbers…”
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Study on the toxic-mechanism of triclosan chronic exposure to zebrafish (Danio rerio) based on gut-brain axis
Published in The Science of the total environment (20-10-2022)“…Triclosan (TCS), as a broad-spectrum bactericide, is extensively used in the fine chemical and textile industries. It is recognized as a new type of…”
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Mechanisms regarding cardiac toxicity triggered by up-regulation of miR-144 in larval zebrafish upon exposure to triclosan
Published in Journal of hazardous materials (05-02-2023)“…Although triclosan (TCS) is ubiquitously detected in environmental media and organisms, little information is available on its cardiotoxicity and underlying…”
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Trichlorocarban induces developmental and immune toxicity to zebrafish (Danio rerio) by targeting TLR4/MyD88/NF-κB signaling pathway
Published in Environmental pollution (1987) (15-03-2021)“…Trichlorocarban (TCC) is ubiquitously detected in environmental matrices, while there is a paucity of information regarding its systemic toxicity. In the…”
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Silver nanoparticles induce liver inflammation through ferroptosis in zebrafish
Published in Chemosphere (Oxford) (01-08-2024)“…As the most widely employed artificial nanomaterials, silver nanoparticles (AgNPs) have been implicated in oxidative stress-induced liver injury. Despite these…”
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MiR-133b as a crucial regulator of TCS-induced cardiotoxicity via activating β-adrenergic receptor signaling pathway in zebrafish embryos
Published in Environmental pollution (1987) (01-10-2023)“…As a commonly used antibacterial agent in daily consumer products, triclosan (TCS) has attracted significant attention due to its potential environmental…”
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Tris (1-chloro-2-propyl) phosphate exposure to zebrafish causes neurodevelopmental toxicity and abnormal locomotor behavior
Published in The Science of the total environment (01-03-2021)“…The organophosphate flame retardant, tris (1-chloro-2-propyl) phosphate (TCPP), is ubiquitous in environmental matrices; however, there is a paucity of…”
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A pure molecular drug hydrogel for post-surgical cancer treatment
Published in Biomaterials (01-01-2021)“…Local drug delivery systems, especially hydrogels, show superior strengths in postoperative recurrence prevention. Despite great advances, clinical translation…”
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Triclosan induced zebrafish immunotoxicity by targeting miR-19a and its gene socs3b to activate IL-6/STAT3 signaling pathway
Published in The Science of the total environment (01-04-2022)“…As a broad-spectrum antibacterial agent, triclosan (TCS) has been confirmed to possess potential immunotoxicity to organisms, but the underlying mechanisms…”
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A Paclitaxel‐Based Mucoadhesive Nanogel with Multivalent Interactions for Cervical Cancer Therapy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-11-2019)“…Cervical cancer treatment is subject to limited drug access to locally diseased targets and generally resistant to chemotherapy, thus it is essential to…”
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Asymmetric Ligands of a Metal–Organic Framework on Enhanced Photocatalytic CO2 Reduction
Published in Inorganic chemistry (02-10-2023)“…Metal–organic frameworks (MOFs) have been studied extensively in the catalytic field. However, the role of ligands in catalysis has been less well…”
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Mechanistic exploration on neurodevelopmental toxicity induced by upregulation of alkbh5 targeted by triclosan exposure to larval zebrafish
Published in Journal of hazardous materials (05-09-2023)“…Because triclosan (TCS) has been confirmed to cause severe neurotoxicity, it is urgent to disclose the underlying toxicity mechanisms at varying levels. TCS…”
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Azithromycin induces neurotoxicity in zebrafish by interfering with the VEGF/Notch signaling pathway
Published in The Science of the total environment (10-12-2023)Get full text
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Neurotoxic effects of 2-ethylhexyl diphenyl phosphate exposure on zebrafish larvae: Insight into inflammation-driven changes in early motor behavior
Published in The Science of the total environment (10-03-2024)“…The extensive utilization and potential adverse impacts of the replacement flame-retardant 2-Ethylhexyl Diphenyl Phosphate (EHDPP) have raised concerns…”
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Enhanced photocatalytic toluene oxidation on CN species modified TiO2: Nitrogen doping state and anti-inactivation mechanism
Published in Applied catalysis. A, General (05-08-2023)“…The photocatalytic oxidation of toluene is limited by low mineralization and inactivation. Cheap carbon and nitrogen (CN) species on TiO2 provides an efficient…”
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