Search Results - "Qian, Kewen"

Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig by Lei, Changhai, Qian, Kewen, Li, Tian, Zhang, Sheng, Fu, Wenyan, Ding, Min, Hu, Shi

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, at the end of 2019, and there are currently no specific antiviral…”
Get full text

CAR exosomes derived from effector CAR-T cells have potent antitumour effects and low toxicity by Fu, Wenyan, Lei, Changhai, Liu, Shuowu, Cui, Yingshu, Wang, Chuqi, Qian, Kewen, Li, Tian, Shen, Yafeng, Fan, Xiaoyan, Lin, Fangxing, Ding, Min, Pan, Mingzhu, Ye, Xuting, Yang, Yongji, Hu, Shi

“…Genetically engineered T cells expressing a chimeric antigen receptor (CAR) are rapidly emerging a promising new treatment for haematological and…”
Get full text

The roles of small extracellular vesicles in cancer and immune regulation and translational potential in cancer therapy by Qian, Kewen, Fu, Wenyan, Li, Tian, Zhao, Jian, Lei, Changhai, Hu, Shi

“…Abstract Extracellular vesicles (EVs) facilitate the extracellular transfer of proteins, lipids, and nucleic acids and mediate intercellular communication…”
Get full text

Ig-like ACE2 protein therapeutics: A revival in development during the COVID-19 pandemic by Qian, Kewen, Hu, Shi

“…While the potential therapeutic utility of angiotensin-converting enzyme 2 (ACE2) is well established, the clinical development of ACE2 drugs has been limited,…”
Get full text

CAR Macrophages for SARS-CoV-2 Immunotherapy by Fu, Wenyan, Lei, Changhai, Ma, Zetong, Qian, Kewen, Li, Tian, Zhao, Jian, Hu, Shi

“…Targeted therapeutics for the treatment of coronavirus disease 2019 (COVID-19), especially severe cases, are currently lacking. As macrophages have unique…”
Get full text

Engineered soluble ACE2 receptor: Responding to change with change by Li, Guangyao, Qian, Kewen, Zhang, Shuyi, Fu, Wenyan, Zhao, Jian, Lei, Changhai, Hu, Shi

“…SARS coronavirus 2 (SARS-CoV-2) invades the human body by binding to major receptors such as ACE2 its S-spike protein, so the interaction of receptor-binding…”
Get full text

The therapeutic potential of exosomes in immunotherapy by Li, Guangyao, Zhang, Shuyi, Zou, Yitan, Ai, Hongru, Zheng, Xinya, Qian, Kewen, Lei, Changhai, Fu, Wenyan

“…Exosomes are found in various tissues of the body and carry abundant contents including nucleic acids, proteins, and metabolites, which continuously flow…”
Get full text

Small extracellular vesicles purification and scale-up by Zheng, Xinya, Ai, Hongru, Qian, Kewen, Li, Guangyao, Zhang, Shuyi, Zou, Yitan, Lei, Changhai, Fu, Wenyan, Hu, Shi

“…Exosomes are small extracellular vesicles (sEVs) secreted by cells. With advances in the study of sEVs, they have shown great potential in the diagnosis and…”
Get full text

CAR‐T‐cell products in solid tumors: Progress, challenges, and strategies by Qian, Kewen, Li, Guangyao, Zhang, Shuyi, Fu, Wenyan, Li, Tian, Zhao, Jian, Lei, Changhai, Wang, Yuqing, Hu, Shi

“…T cells engineered to express chimeric antigen receptors (CARs) with specificity toward tumor cells have led to promising outcomes in patients with…”
Get full text

Therapeutic antibodies under development for SARS‐CoV‐2 by Ma, Zetong, Zhu, MengMei, Zhang, Shuyi, Qian, Kewen, Wang, Chuqi, Fu, Wenyan, Lei, Changhai, Hu, Shi

“…The world is experiencing one of the most difficult moments in history with COVID‐19, which has rapidly developed into a worldwide pandemic with a significant…”
Get full text

Development and characterization of a novel neutralizing scFv vectored immunoprophylaxis against botulinum toxin type A by Wei, Yongpeng, Li, Guangyao, Wang, Zhuo, Qian, Kewen, Zhang, Shuyi, Zhang, Lingling, Lei, Changhai, Hu, Shi

“…Botulinum toxin is a protein toxin secreted by Clostridium botulinum that is strongly neurotoxic. Due to its characteristics of being super toxic, quick…”
Get full text

Exosomes derived from cancer cells relieve inflammatory bowel disease in mice by Zhang, Shuyi, Li, Guangyao, Qian, Kewen, Zou, Yitan, Zheng, Xinya, Ai, Hongru, Lin, Fangxing, Lei, Changhai, Hu, Shi

“…Exosome therapy has garnered significant attention due to its natural delivery capabilities, low toxicity, high biocompatibility, and potential for…”
Get full text

Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency by Fu, Wenyan, Li, Guangyao, Lei, Changhai, Qian, Kewen, Zhang, Shuyi, Zhao, Jian, Hu, Shi

“…Poly ADP ribose polymerase (PARP) inhibitors are mainly used in treating BRCA-mutant cancers, and their application in novel therapies to expand their benefit…”
Get full text

The application of antibody-based agents in cancer therapy based on their mechanisms of action by Qian, Kewen, Li, Guangyao, Zhang, Shuyi, Zou, Yitan, Ai, Hongru, Zheng, Xinya, Fu, Wenyan, Lei, Changhai, Hu, Shi

Get full text

Back Cover: Therapeutic antibodies under development for SARS‐CoV‐2 (View 2/2022) by Ma, Zetong, Zhu, MengMei, Zhang, Shuyi, Qian, Kewen, Wang, Chuqi, Fu, Wenyan, Lei, Changhai, Hu, Shi

“…Research on antibody therapy for SARS‐COV‐2 is in the ascendant, including single antibody therapy and multiple antibody combinations. The multi‐drug…”
Get full text