Search Results - "Qian, Juying"

Hypoxia-challenged MSC-derived exosomes deliver miR-210 to attenuate post-infarction cardiac apoptosis by Cheng, Hao, Chang, Shufu, Xu, Rende, Chen, Lu, Song, Xiaoyue, Wu, Jian, Qian, Juying, Zou, Yunzeng, Ma, Jianying

“…Myocardial infarction (MI) is a major cause of death worldwide. Although percutaneous coronary intervention and coronary artery bypass grafting can prolong…”
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Platelet membrane-coated nanoparticle-mediated targeting delivery of Rapamycin blocks atherosclerotic plaque development and stabilizes plaque in apolipoprotein E-deficient (ApoE−/−) mice by Song, Yanan, Huang, Zheyong, Liu, Xin, Pang, Zhiqing, Chen, Jing, Yang, Hongbo, Zhang, Ning, Cao, Zhonglian, Liu, Ming, Cao, Jiatian, Li, Chenguang, Yang, Xiangdong, Gong, Hui, Qian, Juying, Ge, Junbo

“…Although certain success has been achieved in atherosclerosis treatment, tremendous challenges remain in developing more efficient strategies to treat…”
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Role of KCa3.1 Channels in Macrophage Polarization and Its Relevance in Atherosclerotic Plaque Instability by Xu, Rende, Li, Chenguang, Wu, Yizhe, Shen, Li, Ma, Jianying, Qian, Juying, Ge, Junbo

“…Emerging evidence indicates that proinflammatory macrophage polarization imbalance plays a key role in atherosclerotic plaque progression and instability. The…”
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Rosuvastatin protects against coronary microembolization-induced cardiac injury via inhibiting NLRP3 inflammasome activation by Chen, Ao, Chen, Zhangwei, Zhou, You, Wu, Yuan, Xia, Yan, Lu, Danbo, Fan, Mengkang, Li, Su, Chen, Jinxiang, Sun, Aijun, Zou, Yunzeng, Qian, Juying, Ge, Junbo

“…Coronary microembolization (CME), a common reason for periprocedural myocardial infarction (PMI), bears very important prognostic implications. However, the…”
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Nur77 deficiency exacerbates cardiac fibrosis after myocardial infarction by promoting endothelial‐to‐mesenchymal transition by Chen, Jiahui, Jia, Jianguo, Ma, Leilei, Li, Bingyu, Qin, Qing, Qian, Juying, Ge, Junbo

“…Cardiac fibrosis is a reparative process after myocardial infarction (MI), which leads to cardiac remodeling and finally heart failure…”
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Protective effect of HINT2 on mitochondrial function via repressing MCU complex activation attenuates cardiac microvascular ischemia–reperfusion injury by Li, Su, Chen, Jinxiang, Liu, Muyin, Chen, Yuqiong, Wu, Yuan, Li, Qiyu, Ma, Teng, Gao, Jinfeng, Xia, Yan, Fan, Mengkang, Chen, Ao, Lu, Danbo, Su, Enyong, Xu, Fei, Chen, Zhangwei, Qian, Juying, Ge, Junbo

“…Current evidence indicates that coronary microcirculation is a key target for protecting against cardiac ischemia–reperfusion (I/R) injury. Mitochondrial…”
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Parity and Cardiovascular Disease Mortality: a Dose-Response Meta-Analysis of Cohort Studies by Lv, Haichen, Wu, Hongyi, Yin, Jiasheng, Qian, Juying, Ge, Junbo

“…Parity has been shown to inversely associate with cardiovascular disease (CVD) mortality, but the evidence of epidemiological studies is still controversial…”
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Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload by Zou, Yan, Pan, Le, Shen, Yi, Wang, Xiang, Huang, Chenxing, Wang, Hao, Jin, Xuejuan, Yin, Chao, Wang, Ying, Jia, Jianguo, Qian, Juying, Zou, Yunzeng, Gong, Hui, Ge, Junbo

“…Progressive cardiac fibrosis accelerates the development of heart failure. Here, we aimed to explore serum Wnt5a and Wnt11 levels in hypertension patients, the…”
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COX5A Alleviates Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress, Mitochondrial Dysfunction and Cardiomyocyte Apoptosis by Zhang, Peipei, Lu, Hao, Wu, Yuan, Lu, Danbo, Li, Chenguang, Yang, Xiangdong, Chen, Zhangwei, Qian, Juying, Ge, Junbo

“…Doxorubicin (DOX) as a chemotherapeutic agent can cause mitochondrial dysfunction and heart failure. COX5A has been described as an important regulator of…”
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Functional significance of intermediate coronary stenosis in patients with single-vessel coronary artery disease: A comparison of dynamic SPECT coronary flow reserve with intracoronary pressure-derived fractional flow reserve (FFR) by Li, Chenguang, Xu, Rende, Yao, Kang, Zhang, Jie, Chen, Shuguang, Pang, Lifang, Lu, Hao, Dai, Yuxiang, Qian, Juying, Shi, Hongcheng, Ge, Junbo

“…The aim of this study was to investigate the correlation of coronary flow reserve (CFR) assessed by rest/stress myocardial perfusion imaging with dynamic…”
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Quantitative Profiling of Serum Carnitines Facilitates the Etiology Diagnosis and Prognosis Prediction in Heart Failure by Chen, Zhangwei, Lu, Danbo, Qi, Baoling, Wu, Yuan, Xia, Yan, Chen, Ao, Li, Su, Tang, Huiru, Qian, Juying, Ge, Junbo

“…The perturbation of fatty acid metabolism in heart failure (HF) has been a critical issue. It is unclear whether the amounts of circulating carnitines will…”
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Nicorandil alleviates cardiac microvascular ferroptosis in diabetic cardiomyopathy: Role of the mitochondria-localized AMPK-Parkin-ACSL4 signaling pathway by Chen, Zhangwei, Li, Su, Liu, Muyin, Yin, Ming, Chen, Jinxiang, Li, Youran, Li, Qiyu, Zhou, You, Xia, Yan, Chen, Ao, Lu, Danbo, Li, Chenguang, Chen, Yuqiong, Qian, Juying, Ge, Junbo

“…Mitochondria-associated ferroptosis exacerbates cardiac microvascular dysfunction in diabetic cardiomyopathy (DCM). Nicorandil, an ATP-sensitive K+ channel…”
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Real-world performance of indobufen versus aspirin after percutaneous coronary intervention: insights from the ASPIRATION registry by Dai, Chunfeng, Liu, Muyin, Yang, Zheng, Li, Youran, Zhou, You, Lu, Danbo, Xia, Yan, Chen, Ao, Li, Chenguang, Lu, Hao, Dai, Yuxiang, Ma, Jianying, Chen, Zhangwei, Qian, Juying, Ge, Junbo

“…Indobufen is widely used in patients with aspirin intolerance in East Asia. The OPTION trial launched by our cardiac center examined the performance of…”
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Szabo 2-stent technique for coronary bifurcation lesions: procedural and short-term outcomes by Yang, Hongbo, Qian, Juying, Huang, Zheyong, Ge, Junbo

“…Provisional 1-stent technique is currently regarded as the default approach for the majority of bifurcation lesions. Nonetheless, 2-stent techniques may be…”
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Rosuvastatin Alleviates Coronary Microembolization-Induced Cardiac Injury by Suppressing Nox2-Induced ROS Overproduction and Myocardial Apoptosis by Cao, Yuanyuan, Chen, Zhangwei, Jia, Jianguo, Chen, Ao, Gao, Yanhua, Qian, Juying, Ge, Junbo

“…To explore the mechanism by which rosuvastatin prevents coronary microembolism (CME)-induced cardiac injury and cardiomyocyte apoptosis. Animal and cell models…”
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Efficacy of mesenchymal stem cell therapy in systolic heart failure: a systematic review and meta-analysis by Fan, Mengkang, Huang, Yin, Chen, Zhangwei, Xia, Yan, Chen, Ao, Lu, Danbo, Wu, Yuan, Zhang, Ning, Qian, Juying

“…Heart failure (HF) is the end stage of most heart disease. Mesenchymal stem cells (MSCs), with their specific biological effects, have been applied in several…”
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Development and Validation of a Novel Tool for the Prediction of Clopidogrel Response in Chinese Acute Coronary Syndrome Patients: The GeneFA Score by Wu, Hongyi, Li, Xiaoye, Qian, Juying, Zhao, Xin, Yao, Yao, Lv, Qianzhou, Ge, Junbo

“…Growing evidence indicated that CYP2C19 genotypes could only explain a fraction of the pharmacodynamic response to clopidogrel, while a number of clinical…”
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Epigenetically altered macrophages promote development of diabetes-associated atherosclerosis by Huang, Dong, Gao, Wei, Zhong, Xin, Wu, Hongxian, Zhou, You, Ma, Yuanji, Qian, Juying, Ge, Junbo

“…Atherosclerosis (AS) risk is elevated in diabetic patients, but the underlying mechanism such as involvement of epigenetic control of foam macrophages remains…”
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Targeted neutrophil-mimetic liposomes promote cardiac repair by adsorbing proinflammatory cytokines and regulating the immune microenvironment by Chen, Jing, Song, Yanan, Wang, Qiaozi, Li, Qiyu, Tan, Haipeng, Gao, Jinfeng, Zhang, Ning, Weng, Xueyi, Sun, Dili, Yakufu, Wusiman, Wang, Zhengmin, Qian, Juying, Pang, Zhiqing, Huang, Zheyong, Ge, Junbo

“…Acute myocardial infarction (MI) induces a sterile inflammatory response that may result in poor cardiac remodeling and dysfunction. Despite the progress in…”
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circDENND1B Participates in the Antiatherosclerotic Effect of IL-1β Monoclonal Antibody in Mouse by Promoting Cholesterol Efflux via miR-17-5p/Abca1 Axis by Xu, Fei, Shen, Li, Chen, Han, Wang, Rui, Zang, Tongtong, Qian, Juying, Ge, Junbo

“…Inflammation is a crucial mediator of atherosclerosis, and several therapeutic methods that focus on inflammatory cytokines, including interleukin-1β (IL-1β),…”
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