Search Results - "Qian, Jiawen"
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The IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy
Published in Journal of neuroinflammation (17-10-2018)“…PD-L1 is an immune inhibitory receptor ligand that leads to T cell dysfunction and apoptosis by binding to its receptor PD-1, which works in braking…”
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A review of Aconiti Lateralis Radix Praeparata (Fuzi) for kidney disease: phytochemistry, toxicology, herbal processing, and pharmacology
Published in Frontiers in pharmacology (03-07-2024)“…Aconiti Lateralis Radix Praeparata, commonly known as Fuzi in. traditional Chinese medicine (TCM), is widely utilized in clinical practice despite its inherent…”
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Phytochemistry, pharmacology, toxicology and detoxification of Polygonum multiflorum Thunb.: a comprehensive review
Published in Frontiers in pharmacology (17-06-2024)“…Polygonum multiflorum Thunb. (PM), a kind of perennial plant, belongs to the genus of the family polygonaceae.The dry root of PM (also called Heshouwu), is a…”
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Efficacy and safety of the traditional Chinese formula Shengjiang powder combined with conventional therapy in the treatment of diabetic kidney disease: a systematic review and meta-analysis
Published in Frontiers in endocrinology (Lausanne) (23-07-2024)“…To investigate the efficacy and safety of Shengjiang powder as a treatment for DKD. A comprehensive search was performed in eight databases from their…”
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5
Prognostic value of preoperative lymphocyte‐to‐monocyte ratio in oral cancer patients and establishment of a dynamic nomogram
Published in Oral diseases (01-07-2021)“…Objective To assess the association of preoperative lymphocyte‐to‐monocyte ratio (LMR) and overall survival (OS) in patients with oral cancer and develop a…”
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Association Between Dietary Fatty Acid Pattern and Risk of Oral Cancer
Published in Frontiers in nutrition (Lausanne) (16-05-2022)“…To investigate the association between dietary fatty acid (FA) patterns and the risk of oral cancer. A case-control study which included 446 patients with oral…”
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Relationship Between Dietary Fiber and Vitamin C Intake and Oral Cancer
Published in Frontiers in public health (12-05-2022)“…Dietary fiber and vitamin C has been reported to play a possible role in tumorigenesis. However, few studies have estimated their association with oral cancer…”
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Fcµ Receptor Promotes the Survival and Activation of Marginal Zone B Cells and Protects Mice against Bacterial Sepsis
Published in Frontiers in immunology (05-02-2018)“…The marginal zone B cells (MZB) are located at the interface between the circulation and lymphoid tissue and as a gatekeeper play important roles in both…”
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Brain macrophage development, diversity and dysregulation in health and disease
Published in Cellular & molecular immunology (01-11-2023)“…Brain macrophages include microglia in the parenchyma, border-associated macrophages in the meningeal-choroid plexus-perivascular space, and monocyte-derived…”
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MiR‐15a/16 deficiency enhances anti‐tumor immunity of glioma‐infiltrating CD8+ T cells through targeting mTOR
Published in International journal of cancer (15-11-2017)“…MiR‐15a/16, a miRNA cluster located at chromosome 13q14, has been reported to act as an immune regulator in inflammatory disorders besides its aberrant…”
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TLR1/TLR2 signaling blocks the suppression of monocytic myeloid-derived suppressor cell by promoting its differentiation into M1-type macrophage
Published in Molecular immunology (01-08-2019)“…•Both TLR1 and TLR2 expression predicts favorable prognosis in lung cancer patients.•TLR1/TLR2 signaling greatly inhibits tumor growth and selectively reduces…”
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12
Advances in Brain Delivery Systems Based on Biomimetic Nanoparticles
Published in ChemNanoMat : chemistry of nanomaterials for energy, biology and more (01-06-2022)“…At present, therapeutics for the diseases of central nervous system (CNS) are complicated by the presence of the blood‐brain barrier (BBB). The BBB maintains…”
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Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion
Published in Immunity (Cambridge, Mass.) (14-06-2022)Get full text
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Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma
Published in Cell (04-01-2024)“…Deciphering the cell-state transitions underlying immune adaptation across time is fundamental for advancing biology. Empirical in vivo genomic technologies…”
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Exosomal lncRNA HOTAIR induces PDL1+ B cells to impede anti-tumor immunity in colorectal cancer
Published in Biochemical and biophysical research communications (12-02-2023)“…Regulatory B cells (Bregs) contribute to tumor immunosuppression. However, how B cells acquire their regulatory features in tumors remain unclear. Exosomes are…”
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MicroRNAs 15A and 16–1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2018)“…B cells infiltrate tumors, but little is known about how they affect tumor growth and progression. microRNA15A (MIR15A or miRNA15A) and microRNA16-1 (MIR16-1…”
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Molecular subgroups and B7-H4 expression levels predict responses to dendritic cell vaccines in glioblastoma: an exploratory randomized phase II clinical trial
Published in Cancer Immunology, Immunotherapy (01-11-2018)“…Dendritic cell (DC)-based vaccination is a promising approach for active-specific immunotherapy, but is currently of limited efficacy. The safety and…”
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Classical Monocytes Shuttling for Precise Delivery of Nanotherapeutics to Glioblastoma
Published in Advanced healthcare materials (30-08-2024)“…Glioblastoma (GBM) is the most aggressive brain tumor for which current therapies have limited efficacy. Immunosuppression and difficulties in accessing tumors…”
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Identification and immunological evaluation of novel TLR2 agonists through structure optimization of Pam3CSK4
Published in Bioorganic & medicinal chemistry (01-07-2019)“…[Display omitted] •A novel series of Pam3CSK4 derivatives were designed, prepared, and evaluated for their immune-stimulatory activities based on the study of…”
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MicroRNA 15a/16‐1 suppresses aryl hydrocarbon receptor–dependent interleukin‐22 secretion in CD4+ T cells and contributes to immune‐mediated organ injury
Published in Hepatology (Baltimore, Md.) (01-03-2018)“…Interleukin‐22 (IL‐22), as a link between leukocytic and nonleukocytic cells, has gained increasing attention for its pronounced tissue‐protective properties…”
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