Search Results - "Qian, Chuanyun"
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Epidemiology and outcome of severe sepsis and septic shock in intensive care units in mainland China
Published in PloS one (16-09-2014)“…Information about sepsis in mainland China remains scarce and incomplete. The purpose of this study was to describe the epidemiology and outcome of severe…”
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Differences in epithelial-mesenchymal-transition in paraquat-induced pulmonary fibrosis in BALB/C and BALB/C (nu/nu) nude mice
Published in Biomedicine & pharmacotherapy (01-11-2021)“…Exposure to the toxic herbicide paraquat (PQ) can lead to the active absorption and enrichment of alveolar epithelial cells, resulting in pulmonary fibrosis…”
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Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury
Published in Iranian journal of basic medical sciences (01-01-2024)“…Human umbilical cord mesenchymal stem cells (HUC-MSCs) are pluripotent stem cells with anti-inflammatory and immunomodulatory properties used in the treatment…”
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Clinical efficacy and mechanism of mesenchymal stromal cells in treatment of COVID-19
Published in Stem cell research & therapy (07-02-2022)“…Coronavirus disease 2019 (COVID-19) is a highly infectious epidemic disease that has seriously affected human health worldwide. To date, however, there is…”
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Utilizing reclassification to explore characteristics and prognosis of KDIGOSCr AKI subgroups: a retrospective analysis of a multicenter prospective cohort study
Published in Renal failure (2021)“…Acute kidney injury (AKI) is widespread in the intensive care unit (ICU) and affects patient prognosis. According to Kidney Disease: Improving Global Outcomes…”
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Expert consensus on prevention and cardiopulmonary resuscitation for cardiac arrest in COVID-19
Published in Asian Pacific journal of tropical medicine (01-06-2021)“…Background: Cardiopulmonary resuscitation (CPR) strategies in COVID-19 patients differ from those in patients suffering from cardiogenic cardiac arrest. During…”
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Knowledge and attitudes of healthcare workers in Chinese intensive care units regarding 2009 H1N1 influenza pandemic
Published in BMC infectious diseases (25-01-2011)“…To describe the knowledge and attitudes of critical care clinicians during the 2009 H1N1 influenza pandemic. A survey conducted in 21 intensive care units in…”
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The efficacy of initial ventilation strategy for adult immunocompromised patients with severe acute hypoxemic respiratory failure: study protocol for a multicentre randomized controlled trial (VENIM)
Published in BMC pulmonary medicine (20-09-2017)“…Acute respiratory failure (ARF) is still one of the most severe complications in immunocompromised patients. Our previous systematic review showed noninvasive…”
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Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats
Published in Neural regeneration research (25-05-2012)“…A contusive model of spinal cord injury at spinal segment T8-9 was established in rats. Huantiao (GB30) and Huatuojiaji (Ex-B05) were punctured with needles,…”
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Sirtuin 6 protects the brain from cerebral ischemia/reperfusion injury through NRF2 activation
Published in Neuroscience (16-12-2017)“…•Cerebral I/R can result in decreased SIRT6 expression.•SIRT6 can ameliorate brain damage.•SIRT6 can activate NRF2 and reduce oxidative stress.•NRF2 Knockout…”
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Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells: A case report
Published in Medicine (Baltimore) (31-07-2020)“…The COVID-19 cases increased very fast in January and February 2020. The mortality among critically ill patients, especially the elder ones, is relatively…”
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Exosomes Derived from hucMSCs Primed with IFN-γ Suppress the NF-κB Signal Pathway in LPS-Induced ALI by Modulating the miR-199b-5p/AFTPH Axis
Published in Cell biochemistry and biophysics (01-06-2024)“…Exosomes (exos) are primarily responsible for the process of mesenchymal stem cells (MSCs) treatment for acute lung injury (ALI), but the mechanism remains…”
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The diagnostic value of metagenomic next-generation sequencing in critically ill patients with sepsis: A retrospective cohort study
Published in Medicine (Baltimore) (11-10-2024)“…Metagenomic next-generation sequencing (mNGS) is a new high-throughput sequencing method that may have great importance in early diagnosis and clinical…”
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Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis: The EXIT-SEP Randomized Clinical Trial
Published in JAMA internal medicine (01-07-2023)“…Previous research has suggested that Xuebijing injection (XBJ), an herbal-based intravenous preparation, may reduce mortality among patients with sepsis. To…”
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Understanding the nebulisation of antibiotics: the key role of lung microdialysis studies
Published in Critical care (London, England) (19-02-2024)“…Nebulisation of antibiotics is a promising treatment for ventilator-associated pneumonia (VAP) caused by multidrug-resistant organisms. Ensuring effective…”
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Consensus development of core competencies in intensive and critical care medicine training in China
Published in Critical care (London, England) (16-10-2016)“…The aim of this study is to develop consensus on core competencies required for postgraduate training in intensive care medicine. We used a combination of a…”
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Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial
Published in Critical care (London, England) (16-02-2022)“…Previous cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not…”
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Characteristics of critically ill patients in ICUs in mainland China
Published in Critical care medicine (01-01-2013)“…We sought to describe the demographics, case mix, interventions, and clinical outcome of critically ill patients admitted to ICUs in Mainland China. A 2-month…”
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Identification of candidate genes and pathways in dexmedetomidine-induced neuroprotection in rats using RNA sequencing and bioinformatics analysis
Published in Annals of palliative medicine (01-01-2021)“…Traumatic brain injury (TBI) is a major cause of disability worldwide, without definitive and effective intervention. Dexmedetomidine (DEX) has a…”
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Effects of Shenfu Injection in the Treatment of Septic Shock Patients: A Multicenter, Controlled, Randomized, Open-Label Trial
Published in Evidence-based complementary and alternative medicine (01-01-2016)“…The effect of Shenfu on biochemical parameters and survival during resuscitation in patients with septic shock was examined. This was a multicenter,…”
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