Search Results - "Qi, Yini"
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Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2
Published in Nature communications (27-09-2021)“…There is an urgent need for animal models to study SARS-CoV-2 pathogenicity. Here, we generate and characterize a novel mouse-adapted SARS-CoV-2 strain,…”
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2
Protein arginine methyltransferase 5 in osteoblasts promotes the healing of extraction sockets
Published in Oral diseases (01-09-2024)“…Objectives To explore the effect of protein arginine methyltransferase 5 (PRMT5) on tooth extraction sockets healing, we established an extraction sockets…”
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3
Generation of an Ihh‐mKate2‐Dre knock‐in mouse line
Published in Genesis (New York, N.Y. : 2000) (01-07-2022)“…Summary Indian hedgehog (Ihh), a member of the Hh family, plays important roles in vertebrate development and homeostasis. To improve our understanding of the…”
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PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis
Published in International journal of biological sciences (2022)“…Previous studies have demonstrated the in vitro oncogenic role of protein arginine methyltransferase 5 (PRMT5) in gastric cancer cell lines. The in vivo…”
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Identification of the metaphyseal skeletal stem cell building trabecular bone
Published in Science advances (23-02-2024)“…Skeletal stem cells (SSCs) that are capable of self-renewal and multipotent differentiation contribute to bone development and homeostasis. Several populations…”
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A Gene-Specific Method for Predicting Hemophilia-Causing Point Mutations
Published in Journal of molecular biology (01-11-2013)“…A fundamental goal of medical genetics is the accurate prediction of genotype–phenotype correlations. As an approach to develop more accurate in silico tools…”
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