Search Results - "Qi, Yilun"

Structures of the human Mediator and Mediator-bound preinitiation complex by Chen, Xizi, Yin, Xiaotong, Li, Jiabei, Wu, Zihan, Qi, Yilun, Wang, Xinxin, Liu, Weida, Xu, Yanhui

“…The 1.3-MDa transcription factor IID (TFIID) is required for preinitiation complex (PIC) assembly and RNA polymerase II (Pol II)-mediated transcription…”
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Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase by Zheng, Hai, Qi, Yilun, Hu, Shibin, Cao, Xuan, Xu, Congling, Yin, Zhinang, Chen, Xizi, Li, Yan, Liu, Weida, Li, Jie, Wang, Jiawei, Wei, Gang, Liang, Kaiwei, Chen, Fei Xavier, Xu, Yanhui

“…The 14-subunit metazoan-specific Integrator contains an endonuclease that cleaves nascent RNA transcripts. Here, we identified a complex containing Integrator…”
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Cryo-EM structure of SMG1–SMG8–SMG9 complex by Zhu, Li, Li, Liang, Qi, Yilun, Yu, Zishuo, Xu, Yanhui

“…Nonsense-mediated mRNA decay (NMD) targets premature stop codon (PTC)-containing mRNAs for rapid degradation, and is essential for mammalian embryonic…”
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Structural insights into preinitiation complex assembly on core promoters by Chen, Xizi, Qi, Yilun, Wu, Zihan, Wang, Xinxin, Li, Jiabei, Zhao, Dan, Hou, Haifeng, Li, Yan, Yu, Zishuo, Liu, Weida, Wang, Mo, Ren, Yulei, Li, Ze, Yang, Huirong, Xu, Yanhui

“…Transcription factor IID (TFIID) recognizes core promoters and supports preinitiation complex (PIC) assembly for RNA polymerase II (Pol II)-mediated eukaryotic…”
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Structural insights into the activation of ATM kinase by Xiao, Jianxiong, Liu, Mengjie, Qi, Yilun, Chaban, Yuriy, Gao, Chao, Pan, Beiqing, Tian, Yuan, Yu, Zishuo, Li, Jie, Zhang, Peijun, Xu, Yanhui

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Cryo-EM structure of human mTOR complex 2 by Chen, Xizi, Liu, Mengjie, Tian, Yuan, Li, Jiabei, Qi, Yilun, Zhao, Dan, Wu, Zihan, Huang, Min, Wong, Catherine C. L., Wang, Hong-Wei, Wang, Jiawei, Yang, Huirong, Xu, Yanhui

“…Mechanistic target of rapamycin (mTOR) complex 2 (mTORC2) plays an essential role in regulating cell proliferation through phosphorylating AGC protein kinase…”
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Structural basis of INTAC-regulated transcription by Zheng, Hai, Jin, Qianwei, Wang, Xinxin, Qi, Yilun, Liu, Weida, Ren, Yulei, Zhao, Dan, Chen, Fei Xavier, Cheng, Jingdong, Chen, Xizi, Xu, Yanhui

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RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex by Wang, Xinxin, Qi, Yilun, Wang, Zhenning, Wang, Li, Song, Aixia, Tao, Bolin, Li, Jiabei, Zhao, Dan, Zhang, Hongwei, Jin, Qianwei, Jiang, Yi-Zhou, Chen, Fei Xavier, Xu, Yanhui, Chen, Xizi

“…RNA polymerase II (Pol II)-mediated transcription in metazoans requires precise regulation. RNA Pol II-associated protein 2 (RPAP2) was previously identified…”
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