Search Results - "Qi, Lim Wei"
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Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
Published in Nature communications (17-01-2020)“…Hypoxia of solid tumor compromises the therapeutic outcome of photodynamic therapy (PDT) that relies on localized O 2 molecules to produce highly cytotoxic…”
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A Mesoporous Nanoenzyme Derived from Metal–Organic Frameworks with Endogenous Oxygen Generation to Alleviate Tumor Hypoxia for Significantly Enhanced Photodynamic Therapy
Published in Advanced materials (Weinheim) (01-07-2019)“…Tumor hypoxia compromises the therapeutic efficiency of photodynamic therapy (PDT) as the local oxygen concentration plays an important role in the generation…”
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Catalase-Integrated Hyaluronic Acid as Nanocarriers for Enhanced Photodynamic Therapy in Solid Tumor
Published in ACS nano (23-04-2019)“…Photodynamic therapy (PDT) as a treatment method has many advantages such as minimal invasiveness, repeatable dosage, and low systemic toxicity. Issues with…”
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A Hypoxia‐Responsive Albumin‐Based Nanosystem for Deep Tumor Penetration and Excellent Therapeutic Efficacy
Published in Advanced materials (Weinheim) (01-06-2019)“…Uncontrolled cancer cell proliferation, insufficient blood flow, and inadequate endogenous oxygen lead to hypoxia in tumor tissues. Herein, a unique type of…”
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Nanoscale covalent organic frameworks as smart carriers for drug delivery
Published in Chemical communications (Cambridge, England) (18-03-2016)“…Two porous covalent organic frameworks (COFs) with good biocompatibility were employed as drug nanocarriers, where three different drugs were loaded for…”
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Ultralong room temperature phosphorescence from amorphous organic materials toward confidential information encryption and decryption
Published in Science advances (04-05-2018)“…Ultralong room temperature phosphorescence (URTP) emitted from pure amorphous organic molecules is very rare. Although a few crystalline organic molecules…”
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ZnO–DOX@ZIF‑8 Core–Shell Nanoparticles for pH-Responsive Drug Delivery
Published in ACS biomaterials science & engineering (09-10-2017)“…Developing multifunctional hybrid nanosystems for controlled drug delivery is a challenging task. In this work, we prepared hierarchical core–shell…”
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Independent of EPR Effect: A Smart Delivery Nanosystem for Tracking and Treatment of Nonvascularized Intra‐Abdominal Metastases
Published in Advanced functional materials (12-12-2018)“…Nanoparticle‐based delivery systems (NDS) have impacted the field of cancer therapy on account of the enhanced permeability and retention (EPR) effect that…”
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Versatile bimetallic lanthanide metal-organic frameworks for tunable emission and efficient fluorescence sensing
Published in Communications chemistry (05-04-2018)“…Developing novel lanthanide metal-organic frameworks (Ln-MOFs) to rapidly and reliably differentiate both metal ions in solution and volatile organic compounds…”
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One-step synthesis of amine-coated ultra-small mesoporous silica nanoparticles
Published in Nano research (01-06-2020)“…Silica nanoparticles have been studied extensively in biomedical field due to their high biocompatibility, controllable morphology and so on. They can be used…”
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A Transferrin-Conjugated Hollow Nanoplatform for Redox-Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions: Erratum
Published in Theranostics (01-01-2022)Get full text
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Moist heat as a promising method to decontaminate N95 masks: A large scale clinical study comparing four decontamination modalities—moist heat, steam, ultraviolet-C irradiation, and hydrogen peroxide plasma
Published in International journal of infectious diseases (01-11-2023)“…•The largest study to incorporate mask-wearing into a mask decontamination study.•The study design simulates clinical scenarios of repeated donning and doffing…”
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Autistic traits in first‐episode psychosis: Rates and association with 1‐year recovery outcomes
Published in Early intervention in psychiatry (01-08-2021)“…Aim There is a growing appreciation that subthreshold but clinically elevated levels of autistic traits are clinically relevant. This study examined autistic…”
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Redox-Responsive Polymeric Nanocomplex for Delivery of Cytotoxic Protein and Chemotherapeutics
Published in ACS applied materials & interfaces (04-09-2019)“…Responsive delivery of anticancer proteins into cells is an emerging field in biological therapeutics. Currently, the delivery of proteins is highly…”
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Reduction-sensitive fluorescence enhanced polymeric prodrug nanoparticles for combinational photothermal-chemotherapy
Published in Biomaterials (01-05-2018)“…In this study, a reduction-sensitive supramolecular polymeric drug delivery system was developed for combinational photothermal-chemotherapy of cancer. The…”
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Microneedle-Assisted Topical Delivery of Photodynamically Active Mesoporous Formulation for Combination Therapy of Deep-Seated Melanoma
Published in ACS nano (26-12-2018)“…Topical treatment using photodynamic therapy (PDT) for many types of skin cancers has largely been limited by the inability of existing photosensitizers to…”
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Self-Assembled Oxaliplatin(IV) Prodrug–Porphyrin Conjugate for Combinational Photodynamic Therapy and Chemotherapy
Published in ACS applied materials & interfaces (08-05-2019)“…Nanomedicine has emerged as a promising strategy for effective cancer treatment. A useful approach is to develop carrier-free nanodrugs via a facile…”
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Light-Responsive Prodrug-Based Supramolecular Nanosystems for Site-Specific Combination Therapy of Cancer
Published in Chemistry of materials (14-05-2019)“…On-demand release of chemotherapeutic drugs from their prodrugs triggered by light irradiation has been attracting great attention for effective cancer…”
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Recent advances in multifunctional silica-based hybrid nanocarriers for bioimaging and cancer therapy
Published in Nanoscale (07-07-2016)“…In recent years, there has been a considerable research focus on integrating cancer cell imaging and therapeutic functions into single nanoscale platforms for…”
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Liquid-Crystalline Hydroxyapatite/Polymer Nanorod Hybrids: Potential Bioplatform for Photodynamic Therapy and Cellular Scaffolds
Published in ACS applied materials & interfaces (15-05-2019)“…Recently, we found that self-organization of hydroxyapatite (HAp) with poly(acrylic acid) (PAA) leads to the formation of liquid-crystalline (LC) nanorod…”
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