Search Results - "Qi, Jinxu"

Advances in thiosemicarbazone metal complexes as anti-lung cancer agents by Bai, Xian-Guang, Zheng, Yunyun, Qi, Jinxu

“…The great success of cisplatin as a chemotherapeutic agent considerably increased research efforts in inorganic biochemistry to identify more metallic drugs…”
Get full text

An ultrasensitive electrochemical cytosensor based on the magnetic field assisted binanozymes synergistic catalysis of Fe3O4 nanozyme and reduced graphene oxide/molybdenum disulfide nanozyme by Tian, Liang, Qi, Jinxu, Qian, Kun, Oderinde, Olayinka, Cai, Yingying, Yao, Chen, Song, Wei, Wang, Yihong

“…[Display omitted] •A novel electrochemical biosensor was developed for circulating tumor cells MCF-7 detection.•Magnetic field induced targeted separation and…”
Get full text

A facile DNA strand displacement reaction sensing strategy of electrochemical biosensor based on N-carboxymethyl chitosan/molybdenum carbide nanocomposite for microRNA-21 detection by Tian, Liang, Qi, Jinxu, Ma, Xiangyu, Wang, Xuejiao, Yao, Chen, Song, Wei, Wang, Yihong

“…Herein, we report a facile enzyme-free microRNA (miRNA) target-triggered strand displacement reaction (SDR) amplification strategy with ferrocene (Fc) as a…”
Get full text

Recent progress in thiocarbazone metal complexes for cancer therapy via mitochondrial signalling pathway by Zheng, Yunyun, An, Hangyi, Qi, Jinxu, Li, Jiaming

“…Mitochondria are the energy factories of cells and are important targets for the development of novel tumour treatment strategies owing to their involvement in…”
Get full text

Comparison of ancient and modern Chinese based on complex weighted networks by Cui, Xinru, Qi, Jinxu, Tan, Hao, Chen, Feng

“…In this study, we compare statistical properties of ancient and modern Chinese within the framework of weighted complex networks. We examine two language…”
Get full text

STAT3-induced NCK1 elevation promotes migration of triple-negative breast cancer cells via regulating ERK1/2 signaling by He, Peina, Sheng, Jianyun, Qi, Jinxu, Bai, Xianguang, Li, Jiaxin, Wang, Fubao, Yuan, Yamin, Zheng, Xinhua

“…Background Noncatalytic region of tyrosine kinase 1 (NCK1) plays a key role in extracellular matrix degradation, which is required for the metastasis of…”
Get full text

Molecular characterization of AwSox2 from bivalve Anodonta woodiana: Elucidating its player in the immune response by Xia, Xichao, Guan, Cuiui, Chen, Jiawei, Qiu, Maolin, Qi, Jinxu, Wei, Mengwei, Wang, Xiaowei, Zhang, Ke, Lu, Suxiang, Zhang, Linguo, Hua, Chunxiu, Xue, Shipeng, Yao, Lunguang

“…Sox2 is an embryonal stem cell Ag essential for early embryonic development, tissue homeostasis and immune regulation. In the current study, one complete Sox2…”
Get full text

Gold nanoparticles superlattices assembly for electrochemical biosensor detection of microRNA-21 by Tian, Liang, Qian, Kun, Qi, Jinxu, Liu, Qinyao, Yao, Chen, Song, Wei, Wang, Yihong

“…Gold nanoparticles (AuNPs) superlattice and small molecule dyes such as toluidine blue have remarkable effect on signal amplification. In this report, a…”
Get full text

Piperidylthiosemicarbazones Cu(II) complexes with a high anticancer activity by catalyzing hydrogen peroxide to degrade DNA and promote apoptosis by Qi, Jinxu, Yao, Qian, Tian, Liang, Wang, Yihong

“…Copper(II) complexes efficiently catalyze hydrogen peroxide to generate reactive oxygen species (ROS), which is the major reason for its significant anti-tumor…”
Get full text

Planar intercalated copper (II) complex molecule as small molecule enzyme mimic combined with Fe3O4 nanozyme for bienzyme synergistic catalysis applied to the microRNA biosensor by Tian, Liang, Qi, Jinxu, Oderinde, Olayinka, Yao, Chen, Song, Wei, Wang, Yihong

“…Enzyme mimics have been developed for bioassay of nucleic acids, with some of them involving complicated labeling. Herein, we report a label-free bioassay for…”
Get full text

Copper (II) oxide nanozyme based electrochemical cytosensor for high sensitive detection of circulating tumor cells in breast cancer by Tian, Liang, Qi, Jinxu, Qian, Kun, Oderinde, Olayinka, Liu, Qinyao, Yao, Chen, Song, Wei, Wang, Yihong

“…An ultrasensitive electrochemical detection method was developed to detect circulating tumor cells (CTCs) by using reduced graphene oxide/gold nanoparticles…”
Get full text

Synthesis, crystal structure and antiproliferative mechanisms of gallium() complexes with benzoylpyridine thiosemicarbazones by Qi, Jinxu, Liu, Taichen, Zhao, Wei, Zheng, Xinhua, Wang, Yihong

“…We have prepared six thiosemicarbazone ligands and synthesized the corresponding Ga( iii ) complexes. The antitumor activity of the ligand increases with its…”
Get full text

Advances in molecular agents targeting toll-like receptor 4 signaling pathways for potential treatment of sepsis by Zheng, Yunyun, Gao, Yingying, Zhu, Weiru, Bai, Xian-guang, Qi, Jinxu

“…Sepsis is a systemic inflammatory response syndrome caused by an infection. Toll-like receptor 4 (TLR4) is activated by endogenous molecules released by…”
Get full text

Synthesis, antiproliferative activity and mechanism of gallium(III)-thiosemicarbazone complexes as potential anti-breast cancer agents by Qi, Jinxu, Yao, Qian, Qian, Kun, Tian, Liang, Cheng, Zhen, Yang, Dongmei, Wang, Yihong

“…Five thiosemicarbazone ligands were synthesized and characterized by condensation with different aldehydes or ketones by 4-phenylthiosemicarbazone. The…”
Get full text

Structure−activity relationships of 2‑quinolinecarboxaldehyde thiosemicarbazone gallium(III) complexes with potent and selective anticancer activity by Cao, Wanbao, Qi, Jinxu, Qian, Kun, Tian, Liang, Cheng, Zhen, Wang, Yihong

“…Six gallium(III) complexes (Ga1–Ga6) with 2‑quinolinecarboxaldehyde thiosemicarbazone analogues were synthesized and characterized. These gallium(III)…”
Get full text

Developing Anticancer Ferric Prodrugs Based on the N‑Donor Residues of Human Serum Albumin Carrier IIA Subdomain by Qi, Jinxu, Gou, Yi, Zhang, Yao, Yang, Kun, Chen, Shifang, Liu, Li, Wu, Xiaoyang, Wang, Tao, Zhang, Wei, Yang, Feng

“…To improve the selectivity, delivery, and activity of ferric (Fe) anticancer agents, we design prodrugs based on N-donor residues of the human serum albumin…”
Get full text

Comparative evaluation of the structure and antitumor mechanism of mononuclear and trinucleated thiosemicarbazone Cu(II) complexes by Zheng, Yunyun, Wei, Kai, Gao, Yingying, Zhou, Ziyan, Zheng, Xinhua, Li, Jiuling, Qi, Jinxu

“…The ratio of ligand to Cu(II) ions has an essential effect on the geometrical configuration and anti-tumour activity of metal-based complexes. In this work, we…”
Get full text

Developing an Anticancer Copper(II) Pro-Drug Based on the His242 Residue of the Human Serum Albumin Carrier IIA Subdomain by Qi, Jinxu, Zhang, Yao, Gou, Yi, Zhang, Zhenlei, Zhou, Zuping, Wu, Xiaoyang, Yang, Feng, Liang, Hong

“…To increase delivery efficiency, anticancer activity, and selectivity of anticancer metal agents in vivo, we proposed to develop the anticancer metal pro-drug…”
Get full text

Synthesis of four binuclear copper(II) complexes: Structure, anticancer properties and anticancer mechanism by Qi, Jinxu, Liang, Shichu, Gou, Yi, Zhang, Zhenlei, Zhou, Zuping, Yang, Feng, Liang, Hong

“…Copper (Cu) compounds are a promising candidate for next generation metal anticancer drugs and have been extensively studied. Therefore, four binuclear…”
Get full text

Mechanism of vitamin B6 benzoyl hydrazone platinum(II) complexes overcomes multidrug resistance in lung cancer by Qi, Jinxu, Zheng, Yunyun, Li, Bin, Wei, Lai, Li, Jiuling, Xu, Xiangxiang, Zhao, Shiru, Zheng, Xinhua, Wang, Yihong

“…To overcome the resistance of tumour cells to cis-diaminedichloroplatinum(II) (cisplatin, DDP), we designed and synthesised platinum(II) complexes with copper…”
Get full text