Search Results - "Qi, Jianhuan"
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Continual Deletion of Spinal Microglia Reforms Astrocyte Scar Favoring Axonal Regeneration
Published in Frontiers in pharmacology (27-06-2022)“…Astrocyte scar formation after spinal cord injury (SCI) efficiently limits the accurate damage but physically restricts the following axon regeneration…”
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A Human‐Specific De Novo Gene Promotes Cortical Expansion and Folding
Published in Advanced science (01-03-2023)“…Newly originated de novo genes have been linked to the formation and function of the human brain. However, how a specific gene originates from ancestral…”
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Generation of human otic neuronal organoids using pluripotent stem cells
Published in Cell proliferation (01-05-2023)“…Otic neurons, also known as spiral ganglion neurons (SGNs) in mammalian cochlea, transmit electrical signals from sensory hair cells to cochlear nuclei of the…”
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De novo genes with an lncRNA origin encode unique human brain developmental functionality
Published in Nature ecology & evolution (01-02-2023)“…Human de novo genes can originate from neutral long non-coding RNA (lncRNA) loci and are evolutionarily significant in general, yet how and why this…”
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Reply to: Identification of old coding regions disproves the hominoid de novo status of genes
Published in Nature ecology & evolution (01-10-2024)Get full text
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Adaptive functions of structural variants in human brain development
Published in Science advances (05-04-2024)“…Quantifying the structural variants (SVs) in nonhuman primates could provide a niche to clarify the genetic backgrounds underlying human-specific traits, but…”
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