Search Results - "Qi, Beijie"
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Engineering Bioactive M2 Macrophage‐Polarized, Anti‐inflammatory, miRNA‐Based Liposomes for Functional Muscle Repair: From Exosomal Mechanisms to Biomaterials
Published in Small (Weinheim an der Bergstrasse, Germany) (01-08-2022)“…Severe inflammation and myogenic differentiation disorder are the major obstacles to skeletal muscle healing after injury. MicroRNAs (miRNAs) play an important…”
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Human bone marrow mesenchymal stem cell-derived extracellular vesicles inhibit shoulder stiffness via let-7a/Tgfbr1 axis
Published in Bioactive materials (01-11-2022)“…Shoulder stiffness (SS) is a common shoulder disease characterized by increasing pain and limited range of motion. SS is considered to be an inflammatory and…”
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Exploring the Potential Mechanisms of Melilotus officinalis (L.) Pall. in Chronic Muscle Repair Patterns Using Single Cell Receptor-Ligand Marker Analysis and Molecular Dynamics Simulations
Published in Disease markers (2022)“…Information regarding the function of Melilotus officinalis (L.) Pall. in skeletal muscles is still unknown. In this study, we explored the possible regulatory…”
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si-Tgfbr1-loading liposomes inhibit shoulder capsule fibrosis via mimicking the protective function of exosomes from patients with adhesive capsulitis
Published in Biomaterials research (19-08-2022)“…Abstract Background Adhesive capsulitis is a common shoulder disorder inducing joint capsule fibrosis and pain. When combined with rotator cuff tear (RCT),…”
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Single-Cell Integration Analysis of Heterotopic Ossification and Fibrocartilage Developmental Lineage: Endoplasmic Reticulum Stress Effector Xbp1 Transcriptionally Regulates the Notch Signaling Pathway to Mediate Fibrocartilage Differentiation
Published in Oxidative medicine and cellular longevity (2021)“…Introduction. Regeneration of fibrochondrocytes is essential for the healing of the tendon-bone interface (TBI), which is similar to the formation of…”
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Exercise-induced IL-15 acted as a positive prognostic implication and tumor-suppressed role in pan-cancer
Published in Frontiers in pharmacology (17-11-2022)“…Objective: Exercise can produce a large number of cytokines that may benefit cancer patients, including Interleukin 15 (IL-15). IL-15 is a cytokine that has…”
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A Mesoporous Silica‐Loaded Multi‐Functional Hydrogel Enhanced Tendon Healing via Immunomodulatory and Pro‐Regenerative Effects
Published in Advanced healthcare materials (01-10-2024)“…Tendon injuries are pervasive orthopedic injuries encountered by the general population. Nonetheless, recovery after severe injuries, such as Achilles tendon…”
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Potential Mechanism Underlying Exercise Upregulated Circulating Blood Exosome miR-215-5p to Prevent Necroptosis of Neuronal Cells and a Model for Early Diagnosis of Alzheimer's Disease
Published in Frontiers in aging neuroscience (09-05-2022)“…Exercise is crucial for preventing Alzheimer's disease (AD), although the exact underlying mechanism remains unclear. The construction of an accurate AD risk…”
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Impacts of Nutlin-3a and exercise on murine double minute 2-enriched glioma treatment
Published in Neural regeneration research (01-04-2025)“…JOURNAL/nrgr/04.03/01300535-202504000-00029/figure1/v/2024-07-06T104127Z/r/image-tiff Recent research has demonstrated the impact of physical activity on the…”
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Exercise improves choroid plexus epithelial cells metabolism to prevent glial cell-associated neurodegeneration
Published in Frontiers in pharmacology (16-09-2022)“…Recent studies have shown that physical activities can prevent aging-related neurodegeneration. Exercise improves the metabolic landscape of the body. However,…”
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Agomir-122-loaded nanoparticles coated with cell membrane of activated fibroblasts to treat frozen shoulder based on homologous targeting
Published in Journal of nanobiotechnology (10-04-2024)“…As a common musculoskeletal disorder, frozen shoulder is characterized by thickened joint capsule and limited range of motion, affecting 2-5% of the general…”
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Exercise Modifies the Transcriptional Regulatory Features of Monocytes in Alzheimer's Patients: A Multi-Omics Integration Analysis Based on Single Cell Technology
Published in Frontiers in aging neuroscience (03-05-2022)“…Monocytes have been reported to be important mediators of the protective effect of exercise against the development of Alzheimer's disease (AD). This study…”
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The effect of denture-wearing on physical activity is associated with cognitive impairment in the elderly: A cross-sectional study based on the CHARLS database
Published in Frontiers in neuroscience (16-08-2022)“…Background Currently, only a few studies have examined the link between dental health, cognitive impairment, and physical activity. The current study examined…”
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Exercise potentially prevents colorectal cancer liver metastases by suppressing tumor epithelial cell stemness via RPS4X downregulation
Published in Heliyon (15-03-2024)“…Colorectal cancer (CRC) is the third most prevalent tumor globally. The liver is the most common site for CRC metastasis, and the involvement of the liver is a…”
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Melatonin Alleviates Osteoarthritis by Regulating NADPH Oxidase 4–Induced Ferroptosis and Mitigating Mitochondrial Dysfunction
Published in Journal of pineal research (01-09-2024)“…ABSTRACT Recent evidence indicates that the damaged regions in osteoarthritis are accompanied by the accumulation of iron ions. Ferroptosis, as an…”
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Low-intensity pulsed ultrasound promotes skeletal muscle regeneration via modulating the inflammatory immune microenvironment
Published in International journal of biological sciences (01-01-2023)“…Low-intensity pulsed ultrasound (LIPUS, a form of mechanical stimulation) can promote skeletal muscle functional repair, but a lack of mechanistic…”
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Engineering Bioactive M2 Macrophage‐Polarized, Anti‐inflammatory, miRNA‐Based Liposomes for Functional Muscle Repair: From Exosomal Mechanisms to Biomaterials (Small 34/2022)
Published in Small (Weinheim an der Bergstrasse, Germany) (25-08-2022)“…Macrophage Polarization In article number 2201957, Xiliang Shang, Shiyi Chen, Jiwu Chen, and co‐workers find that myoblast‐derived exosomes modulate macrophage…”
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A Mesoporous Silica‐Loaded Multi‐Functional Hydrogel Enhanced Tendon Healing via Immunomodulatory and Pro‐Regenerative Effects (Adv. Healthcare Mater. 26/2024)
Published in Advanced healthcare materials (18-10-2024)“…Tendon Recovery This cover illustrates the innovative use of CP@SiO2 hydrogel for treating tendon injuries, depicted through an injured rat in a protective…”
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Exercise-Induced Reduction of IGF1R Sumoylation Attenuates Neuroinflammation in APP/PS1 Transgenic Mice
Published in Journal of advanced research (31-03-2024)“…Alzheimer's Disease (AD), a progressive neurodegenerative disorder, is marked by cognitive deterioration and heightened neuroinflammation. The influence of…”
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Macrophage-Myofibroblast Transition as a Potential Origin for Skeletal Muscle Fibrosis After Injury via Complement System Activation
Published in Journal of inflammation research (01-01-2024)“…Acute skeletal muscle injury is common in sports. The injured muscle cannot fully recover due to fibrosis resulting from myofibroblasts. Understanding the…”
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