Search Results - "Qaddoumi, Mohamed G"
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1
Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension
Published in Lipids in health and disease (01-03-2018)“…Hypertension is a risk factor for both cardiovascular diseases (CVDs) and type 2 diabetes (T2D). Angiopoietin-like proteins (ANGPTLs), mainly ANGPTL3, ANGPTL4…”
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2
Increased expression level of ANGPTL8 in white adipose tissue under acute and chronic cold treatment
Published in Lipids in health and disease (26-09-2021)“…Angiopoietin-like proteins (ANGPTL), primarily 3, 4, and 8, play a major role in maintaining energy homeostasis by regulating triglyceride metabolism. This…”
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3
Higher Levels of ANGPTL5 in the Circulation of Subjects With Obesity and Type 2 Diabetes Are Associated With Insulin Resistance
Published in Frontiers in endocrinology (Lausanne) (24-07-2019)“…The family of angiopoietin-like proteins (ANGPTLs) is composed of eight ANGPTLs members that are involved in regulating various metabolic processes and have…”
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4
The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers
Published in Pharmaceutical research (01-04-2004)“…To delineate the characteristics and mechanisms of uptake of biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles in primary cultured rabbit…”
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Evaluation of anticonvulsant actions of dibromophenyl enaminones using in vitro and in vivo seizure models
Published in PloS one (19-06-2014)“…Epilepsy and other seizure disorders are not adequately managed with currently available drugs. We recently synthesized a series of dibromophenyl enaminones…”
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A novel oxazolidinone derivative PH192 demonstrates anticonvulsant activity in vivo in rats and mice
Published in European journal of pharmaceutical sciences (15-03-2019)“…The pharmacotherapeutic management of seizure disorders with currently available medications is not optimal due to side effects and failure of some patients to…”
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Synthesis, neuronal activity and mechanisms of action of halogenated enaminones
Published in European journal of medicinal chemistry (09-04-2014)“…Due to the excellent anticonvulsant activity of previously synthesized halogenated enaminones, more disubstituted analogs were synthesized and evaluated…”
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8
Clathrin and caveolin-1 expression in primary pigmented rabbit conjunctival epithelial cells: role in PLGA nanoparticle endocytosis
Published in Molecular vision (15-10-2003)“…The internalization of poly (dl-lactide-co-glycolide, PLGA) nanoparticles in rabbit conjunctival epithelial cells (RCEC) was previously shown to occur by an…”
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