Search Results - "QUINN, T. M"

A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications by Crocetti, L, Quinn, M T, Schepetkin, I A, Giovannoni, M P

“…Human neutrophil elastase (HNE) is involved in a variety of serious chronic diseases, especially cardiopulmonary pathologies. For this reason, the regulation…”
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Novel Competitive Inhibitor of NAD(P)H Oxidase Assembly Attenuates Vascular O2− and Systolic Blood Pressure in Mice by Rey, F E, Cifuentes, M E, Kiarash, A, Quinn, M T, Pagano, P J

“…We previously reported enhanced expression of the p67 and gp91 components of NAD(P)H oxidase in angiotensin (Ang) II–induced hypertension, suggesting de novo…”
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Symptomatic internal hernias after laparoscopic bariatric surgery by COMEAU, E, GAGNER, M, INABNET, W. B, HERRON, D. M, QUINN, T. M, POMP, A

“…The aim of this study was to describe the occurrence and clinical characteristics of symptomatic internal hernias (IH) after laparoscopic bariatric procedures…”
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p47phox Associates With the Cytoskeleton Through Cortactin in Human Vascular Smooth Muscle Cells: Role in NAD(P)H Oxidase Regulation by Angiotensin II by Touyz, R M, Yao, G, Quinn, M T, Pagano, P J, Schiffrin, E L

“…OBJECTIVE—We tested the hypothesis that p47phox associates with the actin cytoskeleton, enabling site-directed activation of NAD(P)H oxidase, and assessed…”
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Persistent decadal-scale rainfall variability in the tropical South Pacific Convergence Zone through the past six centuries by Maupin, C. R, Partin, J. W, Shen, C.-C, Quinn, T. M, Lin, K, Taylor, F. W, Banner, J. L, Thirumalai, K, Sinclair, D. J

“…Modern Pacific decadal variability (PDV) has global impacts; hence records of PDV from the pre-instrumental period are needed to better inform models that are…”
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Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition by Schepetkin, I A, Khlebnikov, A I, Giovannoni, M P, Kirpotina, L N, Cilibrizzi, A, Quinn, M T

“…Formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) expressed on a variety of cell types. These receptors play an important role in the…”
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Decompressive craniectomy: technical note by Quinn, T. M., Taylor, J. J., Magarik, J. A., Vought, E., Kindy, M. S., Ellegala, D. B.

“…Quinn TM, Taylor JJ, Magarik JA, Vought E, Kindy MS, Ellegala DB. Decompressive craniectomy: technical note. Acta Neurol Scand: 2011: 123: 239–244.© 2010 John…”
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Century-scale movement of the Atlantic Intertropical Convergence Zone linked to solar variability by Poore, R. Z., Quinn, T. M., Verardo, S.

“…The abundance of the planktic foraminifer Globigerinoides sacculifer in Gulf of Mexico (GOM) sediments is a proxy for the influx of Caribbean surface waters…”
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Quantitative structural organization of normal adult human articular cartilage by Hunziker, E.B., Quinn, T.M., Häuselmann, H.-J.

“…Objective Data pertaining to the quantitative structural features and organization of normal articular cartilage are of great importance in understanding its…”
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Diffusion coefficients of articular cartilage for different CT and MRI contrast agents by Kulmala, K.A.M, Korhonen, R.K, Julkunen, P, Jurvelin, J.S, Quinn, T.M, Kröger, H, Töyräs, J

“…Abstract In contrast enhanced magnetic resonance imaging (MRI) and computed tomography (CT), the equilibrium distribution of anionic contrast agent is expected…”
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Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins by DeLeo, Frank R., Quinn, Mark T.

“…Phagocytes such as neutrophils play a key role in the body's innate immune response to infection. These cells travel throughout the body in search of pathogens…”
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NADPH Oxidase Contributes Directly to Oxidative Stress and Apoptosis in Nerve Growth Factor-Deprived Sympathetic Neurons by Tammariello, Steven P, Quinn, Mark T, Estus, Steven

“…Reactive oxygen species (ROS) are necessary for programmed cell death (PCD) in neurons, but the underlying ROS-producing enzymes have not been identified…”
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Matrix and cell injury due to sub-impact loading of adult bovine articular cartilage explants: effects of strain rate and peak stress by Quinn, T.M, Allen, R.G, Schalet, B.J, Perumbuli, P, Hunziker, E.B

“…Mechanical overloading of cartilage has been implicated in the initiation and progression of osteoarthrosis. Our objectives were to identify threshold levels…”
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Superoxide Anion From the Adventitia of the Rat Thoracic Aorta Inactivates Nitric Oxide by Wang, Hui Di, Pagano, Patrick J, Du, Yue, Cayatte, Antonio J, Quinn, Mark T, Brecher, Peter, Cohen, Richard A

“…The purpose of this study was to determine whether superoxide anion is produced endogenously in the rat aortic adventitia and whether sufficient superoxide…”
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Effects of injurious compression on matrix turnover around individual cells in calf articular cartilage explants by Quinn, T M, Grodzinsky, A J, Hunziker, E B, Sandy, J D

“…The effects of mechanical injury on the metabolism of cartilage matrix are of interest for understanding the pathogenesis of osteoarthrosis and the development…”
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Effects of damage in the articular surface on the cartilage response to injurious compression in vitro by Morel, V., Berutto, C., Quinn, T.M.

“…Macroscopic structural damage to the cartilage articular surface can occur due to slicing in surgery, cracking in mechanical trauma, or fibrillation in early…”
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Lysophosphatidylcholine: A Chemotactic Factor for Human Monocytes and Its Potential Role in Atherogenesis by Quinn, Mark T., Parthasarathy, Sampath, Steinberg, Daniel

“…Native low density lipoprotein (LDL) does not affect monocyte/macrophage motility. On the other hand, oxidatively modified LDL inhibits the motility of…”
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Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components by QUINN, M. T, EVANS, T, LOETTERLE, L. R, JASAITIS, A. J, BOKOCH, G. M

“…Activation of the superoxide-generating NADPH oxidase system of human neutrophils involves the assembly of several neutrophil components, some located on the…”
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Static compression of articular cartilage can reduce solute diffusivity and partitioning: implications for the chondrocyte biological response by Quinn, T.M., Morel, V., Meister, J.J.

“…Chondrocytes depend upon solute transport within the avascular extracellular matrix of adult articular cartilage for many of their biological activities…”
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Modulation of Endotoxin- and Enterotoxin-Induced Cytokine Release by In Vivo Treatment with β-(1,6)-Branched β-(1,3)-Glucan by SOLTYS, J, QUINN, M. T

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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