Search Results - "QUERTINMONT, E"

Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis by Franchimont, D, Vermeire, S, El Housni, H, Pierik, M, Van Steen, K, Gustot, T, Quertinmont, E, Abramowicz, M, Van Gossum, A, Devière, J, Rutgeerts, P

“…Background and aims: Elicitation of an innate immune response to bacterial products is mediated through pattern recognition receptors (PRRs) such as the…”
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Hepatic expression of CCL2 in alcoholic liver disease is associated with disease severity and neutrophil infiltrates by Degré, D., Lemmers, A., Gustot, T., Ouziel, R., Trépo, E., Demetter, P., Verset, L., Quertinmont, E., Vercruysse, V., Le Moine, O., Devière, J., Moreno, C.

“…Summary Serum levels and liver expression of CCL2 are increased in patients with alcoholic hepatitis (AH). In an experimental model of alcoholic liver disease…”
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O054 TM6SF2-T and PNPLA3-G genetic variants co-modulate the risk of hepatocellular carcinoma in caucasian patients with alcoholic cirrhosis. Inter-cohort validation in 1068 patients by Nahon, P, Cao, Q, Guyot, E, Rufat, P, Sutton, A, Ganne-Carrié, N, Ziol, M, Gustot, T, Quertinmont, E, Devière, J, Degré, D, Schreiber, J, Labkriman, A, Charnaux, N, Moreno, C, Trinchet, J.-C, Franchimont, D, Zucman-Rossi, J, Trepo, E

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inhibitor of interleukin-6 trans-signalling, sgp130, contributes to impaired acute phase response in human chronic liver disease by Lemmers, A, Gustot, T, Durnez, A, Evrard, S, Moreno, C, Quertinmont, E, Vercruysse, V, Demetter, P, Franchimont, D, Le Moine, O, Geerts, A, Devière, J

“…In chronic liver disease, high circulating interleukin (IL)-6 contrasts with a poor acute phase response. We evaluated the impact of liver and circulating…”
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Profile of soluble cytokine receptors in Crohn’s disease by Gustot, T, Lemmers, A, Louis, E, Nicaise, C, Quertinmont, E, Belaiche, J, Roland, S, Van Gossum, A, Devière, J, Franchimont, D

“…Introduction: Soluble cytokine receptors (sCRs) modulate the in vivo activity of cytokines. Deficient sCR production could participate in the pathogenesis and…”
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120 SEVERE VITAMIN D DEFICIENCY IS ASSOCIATED WITH COMPLICATIONS OF PORTAL HYPERTENSION AND A WORSE PROGNOSIS IN ALCOHOLIC CIRRHOSIS by Trépo, E, Ouziel, R, Pradat, P, Momozawa, Y, Quertinmont, E, Gervy, C, Gustot, T, Degré, D, Vercruysse, V, Deltenre, P, Verset, L, Gulbis, B, Franchimont, D, Devière, J, Lemmers, A, Moreno, C

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1373 VITAMIN D DEFICIENCY IS ASSOCIATED WITH SEVERITY AND MORTALITY, AND MAY WORSEN INFLAMMATION AND FIBROSIS, IN ALCOHOLIC LIVER DISEASE by Trépo, E, Ouziel, R, Pradat, P, Momozawa, Y, Quertinmont, E, Gervy, C, Gustot, T, Degré, D, Vercruysse, V, Deltenre, P, Gulbis, B, Franchimont, D, Deviere, J, Lemmers, A

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490 HIGHLY EXPRESSED CCL-2 IN SEVERE FORM OF ALCOHOLIC HEPATITIS: A POTENTIAL ENHANCER OF THE IL-17-NEUTROPHIL LIVER RECRUITMENT PATHWAY by Degré, P, Lemmers, A, Gustot, T, Trépo, E, Ouziel, R, Demetter, P, Verset, L, Quertinmont, E, Vercruysse, V, Le Moine, O, Devière, J, Moreno, C

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124 IMPACT OF PNPLA3 (RS738409 C>G) POLYMORPHISM ON FIBROSIS PROGRESSION AND STEATOSIS IN CHRONIC HEPATITIS C by Trépo, E, Pradat, P, Potthoff, A, Gustot, T, Lemmers, A, Quertinmont, E, Berthillon, P, Deviére, J, Manns, M, Trépo, C, Wedemeyer, H, Franchimont, D, Moreno, C

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Production and role of interleukin‐10 in concanavalin A–induced hepatitis in mice by Louis, H, Le Moine, O, Peny, M, Quertinmont, E, Fokan, D, Goldman, M, Deviere, J

“…Experimental T‐cell‐mediated hepatitis induced by concanavalin A (Con A) involves the production of proinflammatory cytokines. Because interleukin (IL)‐10 is a…”
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790 PLASMA SOLUBLE ST2 RECEPTOR IS INCREASED IN HUMAN ALCOHOLIC LIVER DISEASE AND CORRELATES WITH THE PROGNOSTIC INDEX IN ALCOHOLIC HEPATITIS by Lemmers, A, Moreno, C, Ouziel, R, Degré, D, Trepo, E, Quertinmont, E, Vercruysse, V, Le Moine, O, Devière, J, Gustot, T

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The interleukin‐17 pathway is involved in human alcoholic liver disease by Lemmers, Arnaud, Moreno, Christophe, Gustot, Thierry, Maréchal, Raphaël, Degré, Delphine, Demetter, Pieter, de Nadai, Patricia, Geerts, Albert, Quertinmont, Eric, Vercruysse, Vincent, Le Moine, Olivier, Devière, Jacques

“…Immune dysregulations in alcoholic liver diseases are still unclear, especially regarding alcoholic hepatitis inflammatory burst. Interleukin‐17 (IL‐17) is…”
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Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver by GUSTOT, Thierry, LEMMERS, Arnaud, MORENO, Christophe, NAGY, Nathalie, QUERTINMONT, Eric, NICAISE, Charles, FRANCHIMONT, Denis, LOUIS, Hubert, DEVIERE, Jacques, LE MOINE, Olivier

“…Gut-derived, endotoxin-mediated hepatocellular damage has been postulated to play a crucial role in the pathogenesis of alcohol-induced liver injury in…”
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P753 Vedolizumab trough levels during induction in IBD patients: A longitudinal observational retrospective study by Liefferinckx, C, Cremer, A, Minsart, C, Gils, A, Amininejad, L, Tafciu, V, Quertinmont, E, Devière, J, Van Gossum, A, Franchimont, D

“…Abstract Background Vedolizumab (VDZ) is effective for the treatment of ulcerative colitis (UC) or Crohn’s disease (CD). Few real-world experience data are…”
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P560 Trough levels at induction: impact on long term response when re-initiating infliximab by Liefferinckx, C., Minsart, C., Toubeau, J.-F., Cremer, A., Amininejad, L., Quertinmont, E., Devière, J., Gils, A., Van Gossum, A., Franchimont, D.

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Impact of Infliximab on Serum Leptin Levels in Patients with Crohn’s Disease by Franchimont, Denis, Roland, Sandrine, Gustot, Thierry, Quertinmont, Eric, Toubouti, Youssef, Gervy, Marie-Christine, Deviere, Jacques, Van Gossum, Andre

“…Objectives: In mice, body weight is regulated by adipocyte-derived leptin. TNFα is a critical mediator of inflammation-induced cachexia in Crohn’s disease…”
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Interleukin‐10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice by Louis, Hubert, Van Laethem, Jean‐Luc, Wu, Wei, Quertinmont, Eric, Degraef, Chantal, Van den Berg, Kit, Demols, Anne, Goldman, Michel, Le Moine, Olivier, Geerts, Albert, Devière, Jacques

“…The role of the anti‐inflammatory cytokine interleukin‐10 (IL‐10) was investigated in the mouse model of liver injury induced by carbon tetrachloride (CCl4)…”
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Endogenous interleukin-10 modulates fibrosis and regeneration in experimental chronic pancreatitis by Demols, Anne, Van Laethem, Jean-Luc, Quertinmont, Eric, Degraef, Chantal, Delhaye, Myriam, Geerts, Albert, Deviere, Jacques

“…Interleukin (IL)-10, a potent anti-inflammatory cytokine, limits the severity of acute pancreatitis and downregulates transforming growth factor (TGF)-beta…”
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CD4 + T cells play an important role in acute experimental pancreatitis in mice by DEMOLS, A, LE MOINE, O, DESALLE, F, QUERTINMONT, E, VAN LAETHEM, J.-L, DEVIERE, J

“…Background & Aims: Few data are available on the potential role of T lymphocytes in experimental acute pancreatitis. The aim of this study was to characterize…”
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Cold liver ischemia‐reperfusion injury critically depends on liver T cells and is improved by donor pretreatment with interleukin 10 in mice by Le Moine, Olivier, Louis, Hubert, Demols, Anne, Desalle, Fabrice, Demoor, François, Quertinmont, Eric, Goldman, Michel, Devière, Jacques

“…Kupffer cells are thought to mediate most of the deleterious effects of liver ischemia‐reperfusion injury. The role of liver T cells and the impact of resident…”
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