Search Results - "QUAX, Paul H"

The Intriguing World of Vascular Remodeling, Angiogenesis, and Arteriogenesis by Quax, Paul H A, Deindl, Elisabeth

“…Vascular remodeling is a very general feature related to angiogenesis and arteriogenesis, which are involved in neovascularization processes [...]…”
Get full text

T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword by Simons, Karin H., de Jong, Alwin, Jukema, J. Wouter, de Vries, Margreet R., Arens, Ramon, Quax, Paul H. A.

“…The role of inflammation in cardiovascular disease (CVD) is now widely accepted. Immune cells, including T cells, are influenced by inflammatory signals and…”
Get full text

Preoperative methionine restriction induces perivascular adipose tissue browning and improves vein graft remodeling in male mice by Kip, Peter, Sluiter, Thijs J., MacArthur, Michael R., Tao, Ming, Kruit, Nicky, Mitchell, Sarah J., Jung, Jonathan, Kooijman, Sander, Gorham, Josh, Seidman, Jonathan G., Quax, Paul H. A., Decano, Julius L., Aikawa, Masanori, Ozaki, C. Keith, Mitchell, James R., de Vries, Margreet R.

“…Short-term preoperative methionine restriction (MetR) is a promising translatable strategy to mitigate surgical injury response. However, its application to…”
Get full text

Vein graft failure: from pathophysiology to clinical outcomes by de Vries, Margreet R., Simons, Karin H., Jukema, J. Wouter, Braun, Jerry, Quax, Paul H. A.

“…Key Points Thrombosis, constrictive remodelling, intimal hyperplasia, and unstable atherosclerotic lesions are the critical mechanisms contributing to vein…”
Get full text

The Multifaceted Functions of CXCL10 in Cardiovascular Disease by van den Borne, Pleunie, Quax, Paul H. A., Hoefer, Imo E., Pasterkamp, Gerard

“…C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for…”
Get full text

Exploring the Effects of Human Bone Marrow-Derived Mononuclear Cells on Angiogenesis In Vitro by Peeters, Judith A. H. M, Peters, Hendrika A. B, Videler, Anique J, Hamming, Jaap F, Schepers, Abbey, Quax, Paul H. A

“…Cell therapies involving the administration of bone marrow-derived mononuclear cells (BM-MNCs) for patients with chronic limb-threatening ischemia (CLTI) have…”
Get full text

PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting by Perrotta, Paola, de Vries, Margreet R., Peeters, Bart, Guns, Pieter-Jan, De Meyer, Guido R. Y., Quax, Paul H. A., Martinet, Wim

“…Vein grafting is a frequently used surgical intervention for cardiac revascularization. However, vein grafts display regions with intraplaque (IP)…”
Get full text

Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension by Tura-Ceide, Olga, Smolders, Valérie F. E. D., Aventin, Núria, Morén, Constanza, Guitart-Mampel, Mariona, Blanco, Isabel, Piccari, Lucilla, Osorio, Jeisson, Rodríguez, Cristina, Rigol, Montserrat, Solanes, Núria, Malandrino, Andrea, Kurakula, Kondababu, Goumans, Marie Jose, Quax, Paul H. A., Peinado, Victor I., Castellà, Manuel, Barberà, Joan Albert

“…Pulmonary endarterectomy (PEA) resected material offers a unique opportunity to develop an in vitro endothelial cell model of chronic thromboembolic pulmonary…”
Get full text

The Cortisol Response of Male and Female Choroidal Endothelial Cells: Implications for Central Serous Chorioretinopathy by Brinks, Joost, van Dijk, Elon H C, Kiełbasa, Szymon M, Mei, Hailiang, van der Veen, Isa, Peters, Hendrika A B, Sips, Hetty C M, Notenboom, Robbert G E, Quax, Paul H A, Boon, Camiel J F, Meijer, Onno C

“…Central serous chorioretinopathy (CSC) is a severe ocular disease characterized by fluid accumulation under the retina and abnormalities in the underlying…”
Get full text

In Vivo Matrigel Plug Assay as a Potent Method to Investigate Specific Individual Contribution of Angiogenesis to Blood Flow Recovery in Mice by Aref, Zeen, Quax, Paul H. A.

“…Neovascularization restores blood flow recovery after ischemia in peripheral arterial disease. The main two components of neovascularization are angiogenesis…”
Get full text

Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization by Baganha, Fabiana, de Jong, Rob C. M., Peters, Erna A., Voorham, Wietske, Jukema, J. Wouter, Delibegovic, Mirela, de Vries, Margreet R., Quax, Paul H. A.

“…Objective Statins pleiotropically provide additional benefits in reducing atherosclerosis, but their effects on intraplaque angiogenesis (IPA) and hemorrhage…”
Get full text

Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE3-Leiden mice following myocardial ischemia-reperfusion injury by Pluijmert, Niek J, den Haan, Melina C, van Zuylen, Vanessa L, Steendijk, Paul, de Boer, Hetty C, van Zonneveld, Anton J, Fibbe, Willem E, Schalij, Martin J, Quax, Paul H A, Atsma, Douwe E

“…Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of…”
Get full text

Wnt but Not BMP Signaling Is Involved in the Inhibitory Action of Sclerostin on BMP‐Stimulated Bone Formation by van Bezooijen, Rutger L, Svensson, J Peter, Eefting, Daniël, Visser, Annemieke, van der Horst, Geertje, Karperien, Marcel, Quax, Paul HA, Vrieling, Harry, Papapoulos, Socrates E, ten Dijke, Peter, Löwik, Clemens WGM

“…Sclerostin is an osteocyte‐derived negative regulator of bone formation. It inhibits BMP‐stimulated bone formation both in vitro and in vivo but has no direct…”
Get full text

Arteriogenesis and Therapeutic Angiogenesis-An Update by Deindl, Elisabeth, Quax, Paul H A

“…Vascular occlusive diseases such myocardial infarction, peripheral artery disease of the lower extremities, or stroke still represent a substantial health…”
Get full text

The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development by de Jong, Rob C M, Ewing, Mark M, de Vries, Margreet R, Karper, Jacco C, Bastiaansen, Antonius J N M, Peters, Hendrika A B, Baghana, Fabiana, van den Elsen, Peter J, Gongora, Céline, Jukema, J Wouter, Quax, Paul H A

“…Genetic P300/CBP-associated factor (PCAF) variation affects restenosis-risk in patients. PCAF has lysine acetyltransferase activity and promotes nuclear factor…”
Get full text

Lack of Fibronectin-EDA Promotes Survival and Prevents Adverse Remodeling and Heart Function Deterioration After Myocardial Infarction by Arslan, Fatih, Smeets, Mirjam B, Riem Vis, Paul W, Karper, Jacco C, Quax, Paul H, Bongartz, Lennart G, Peters, John H, Hoefer, Imo E, Doevendans, Pieter A, Pasterkamp, Gerard, de Kleijn, Dominique P

“…RATIONALE:The extracellular matrix may induce detrimental inflammatory responses on degradation, causing adverse cardiac remodeling and heart failure. The…”
Get full text

Decreased Glycolysis as Metabolic Fingerprint of Endothelial Cells in Chronic Thromboembolic Pulmonary Hypertension by Smolders, Valérie F E D, Rodríguez, Cristina, Morén, Constanza, Blanco, Isabel, Osorio, Jeisson, Piccari, Lucilla, Bonjoch, Cristina, Quax, Paul H A, Peinado, Victor I, Castellà, Manuel, Barberà, Joan Albert, Cascante, Marta, Tura-Ceide, Olga

Get full text

MicroRNA-411 and Its 5′-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia by van der Kwast, Reginald V.C.T., Woudenberg, Tamar, Quax, Paul H.A., Nossent, A. Yaël

“…MicroRNAs are posttranscriptional regulators of gene expression. As microRNAs can target many genes simultaneously, microRNAs can regulate complex…”
Get full text

Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease by Pons, Douwe, de Vries, Florentine R., van den Elsen, Peter J., Heijmans, Bastiaan T., Quax, Paul H.A., Jukema, J. Wouter

“…Significant progress has been made in the clinical management of a variety of cardiovascular diseases. Nevertheless, the therapeutic efficacy of the current…”
Get full text

Inflammation in Vein Graft Disease by de Vries, Margreet R, Quax, Paul H A

“…Bypass surgery is one of the most frequently used strategies to revascularize tissues downstream occlusive atherosclerotic lesions. For venous bypass surgery…”
Get full text