Search Results - "QINFANG LIU"

Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration by Liu, Qinfang, Bautista-Gomez, Judith, Higgins, Daniel A, Yu, Jianzhong, Xiong, Yulan

“…Mutations in the kinase LRRK2 and impaired endocytic trafficking are both implicated in the pathogenesis of Parkinson's disease (PD). Expression of the…”
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A Single Mutation at Position 190 in Hemagglutinin Enhances Binding Affinity for Human Type Sialic Acid Receptor and Replication of H9N2 Avian Influenza Virus in Mice by Teng, Qiaoyang, Xu, Dawei, Shen, Weixia, Liu, Qinfang, Rong, Guangyu, Li, Xuesong, Yan, Liping, Yang, Jianmei, Chen, Hongjun, Yu, Hai, Ma, Wenjun, Li, Zejun

“…H9N2 avian influenza virus (AIV) has an extended host range, but the molecular basis underlying H9N2 AIV transmission to mammals remains unclear. We isolated…”
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Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice by Xiong, Yulan, Neifert, Stewart, Karuppagounder, Senthilkumar S., Liu, Qinfang, Stankowski, Jeannette N., Lee, Byoung Dae, Ko, Han Seok, Lee, Yunjong, Grima, Jonathan C., Mao, Xiaobo, Jiang, Haisong, Kang, Sung-Ung, Swing, Deborah A., Iacovitti, Lorraine, Tessarollo, Lino, Dawson, Ted M., Dawson, Valina L.

“…Mutations in LRRK2 are known to be the most common genetic cause of sporadic and familial Parkinson’s disease (PD). Multiple lines of LRRK2 transgenic or…”
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Different serotypes of Escherichia coli flagellin exert identical adjuvant effects by Pang, Shengmei, Wu, Wenwen, Liu, Qinfang, Zhu, Guoqiang, Duan, Qiangde

“…Bacterial flagellin is a potent powerful adjuvant, which exerts its adjuvant activity by activating the Toll-like receptor 5 (TLR5) signaling pathway to induce…”
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Generation and characterization of chimeric Tembusu viruses containing pre-membrane and envelope genes of Japanese encephalitis virus by Xu, Bangfeng, Liu, Xingpo, Yan, Dawei, Teng, Qiaoyang, Yuan, Chunxiu, Zhang, Zhifei, Liu, Qinfang, Li, Zejun

“…Since its outbreak in 2010, Tembusu virus (TMUV) has spread widely throughout China and Southeast Asia, causing significant economic losses to the poultry…”
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Evolution and pathogenicity of H6 avian influenza viruses isolated from Southern China during 2011 to 2017 in mice and chickens by Lin, Weishan, Cui, Hongrui, Teng, Qiaoyang, Li, Luzhao, Shi, Ying, Li, Xuesong, Yang, Jianmei, Liu, Qinfang, Deng, Junliang, Li, Zejun

“…H6 subtype avian influenza viruses spread widely in birds and pose potential threats to poultry and mammals, even to human beings. In this study, the evolution…”
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Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity by Wu, Wei, Qu, Yang, Yu, Shengqing, Wang, Sa, Yin, Yuncong, Liu, Qinfang, Meng, Chunchun, Liao, Ying, Ur Rehman, Zaib, Tan, Lei, Song, Cuiping, Qiu, Xusheng, Liu, Weiwei, Ding, Chan, Sun, Yingjie

“…DEAD (Glu-Asp-Ala-Glu) box RNA helicases have been proven to contribute to antiviral innate immunity. The DDX21 RNA helicase was identified as a nuclear…”
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Efficacy of a recombinant turkey herpesvirus (H9) vaccine against H9N2 avian influenza virus in chickens with maternal-derived antibodies by Pan, Xue, Liu, Qinfang, Niu, Shiqi, Huang, Dongming, Yan, Dawei, Teng, Qiaoyang, Li, Xuesong, Beerens, Nancy, Forlenza, Maria, de Jong, Mart C M, Li, Zejun

“…Although vaccines have been widely used for many years, they have failed to control H9N2 avian influenza virus (AIV) in the field in China. The high level of…”
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Impacts of different expressions of PA-X protein on 2009 pandemic H1N1 virus replication, pathogenicity and host immune responses by Lee, Jinhwa, Yu, Hai, Li, Yonghai, Ma, Jingjiao, Lang, Yuekun, Duff, Michael, Henningson, Jamie, Liu, Qinfang, Li, Yuhao, Nagy, Abdou, Bawa, Bhupinder, Li, Zejun, Tong, Guangzhi, Richt, Juergen A, Ma, Wenjun

“…Abstract Although several studies have investigated the functions of influenza PA-X, the impact of different expressions of PA-X protein including full-length,…”
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Biological Characteristics of Infectious Laryngotracheitis Viruses Isolated in China by Wu, Mi, Zhang, Zhifei, Su, Xin, Lu, Haipeng, Li, Xuesong, Yuan, Chunxiu, Liu, Qinfang, Teng, Qiaoyang, Geri, Letu, Li, Zejun

“…Infectious laryngotracheitis virus (ILTV) causes severe respiratory disease in chickens and results in huge economic losses in the poultry industry worldwide…”
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326K at E Protein Is Critical for Mammalian Adaption of TMUV by Liu, Xingpo, Yan, Dawei, Peng, Shan, Zhang, Yuee, Xu, Bangfeng, Li, Luzhao, Shi, Xiaona, Ma, Tianxin, Li, Xuesong, Teng, Qiaoyang, Yuan, Chunxiu, Liu, Qinfang, Li, Zejun

“…Outbreaks of Tembusu virus (TMUV) infection have caused huge economic losses to the poultry industry in China since 2010. However, the potential threat of TMUV…”
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Cross-Species Genome-Wide Analysis Reveals Molecular and Functional Diversity of the Unconventional Interferon-ω Subtype by Shields, Lauren E, Jennings, Jordan, Liu, Qinfang, Lee, Jinhwa, Ma, Wenjun, Blecha, Frank, Miller, Laura C, Sang, Yongming

“…Innate immune interferons (IFNs), particularly type I IFNs, are primary mediators regulating animal antiviral, antitumor, and cell-proliferative activity…”
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Combination of PB2 271A and SR Polymorphism at Positions 590/591 Is Critical for Viral Replication and Virulence of Swine Influenza Virus in Cultured Cells and In Vivo by QINFANG LIU, CHUANLING QIAO, MARJUKI, Henju, BAWA, Bhupinder, JINGQUN MA, GUILLOSSOU, Stephane, WEBBY, Richard J, RICHT, Jürgen A, WENJUN MA

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The PB1 gene from H9N2 avian influenza virus showed high compatibility and increased mutation rate after reassorting with a human H1N1 influenza virus by Cui, Hongrui, Che, Guangsheng, de Jong, Mart C M, Li, Xuesong, Liu, Qinfang, Yang, Jianmei, Teng, Qiaoyang, Li, Zejun, Beerens, Nancy

“…Reassortment between human and avian influenza viruses (AIV) may result in novel viruses with new characteristics that may threaten human health when causing…”
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A Single Mutation at Position 120 in the Envelope Protein Attenuates Tembusu Virus in Ducks by Yan, Dawei, Wang, Binbin, Shi, Ying, Ni, Xintao, Wu, Xiaogang, Li, Xuesong, Liu, Xingpo, Wang, Haiwang, Su, Xin, Teng, Qiaoyang, Yang, Jianmei, Liu, Qinfang, Li, Zejun

“…A live attenuated duck Tembusu virus (TMUV) vaccine FX2010-180P (180P) was successfully utilized to prevent TMUV infections in ducks in China. Compared with…”
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Toxic Effects and Mechanism of Pefloxacin on the Early Life Stage of Zebrafish (Danio rerio) by Shen, Rong, Yu, Yichang, Liu, Qinfang, Wang, Ruili, Lan, Rong, Feng, Hui, Yu, Ran, Jin, Lihua, Li, Ye

“…Pefloxacin (PFLX) is a type of fluoroquinolone (FQ) that has been widely used in aquaculture and animal husbandry. It is also a new kind of pseudo-persistent…”
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Characterization of uncultivable bat influenza virus using a replicative synthetic virus by Zhou, Bin, Ma, Jingjiao, Liu, Qinfang, Bawa, Bhupinder, Wang, Wei, Shabman, Reed S, Duff, Michael, Lee, Jinhwa, Lang, Yuekun, Cao, Nan, Nagy, Abdou, Lin, Xudong, Stockwell, Timothy B, Richt, Juergen A, Wentworth, David E, Ma, Wenjun

“…Bats harbor many viruses, which are periodically transmitted to humans resulting in outbreaks of disease (e.g., Ebola, SARS-CoV). Recently, influenza…”
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RNA-Seq Analysis of Influenza A Virus-Induced Transcriptional Changes in Mice Lung and Its Possible Implications for the Virus Pathogenicity in Mice by Ma, Tianxin, Nagy, Abdou, Xu, Guanlong, Xin, Lingxiang, Bao, Danqi, Lu, Chenyang, Niu, Shiqi, Wu, Zihua, Ren, Chaochao, Zhang, Ting, Yang, Jianmei, Teng, Qiaoyang, Li, Xuesong, Li, Zejun, Liu, Qinfang

“…The influenza A virus (IAV) is an important cause of respiratory disease worldwide. It is well known that alveolar epithelial cells are the target cells for…”
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Molecular and Antigenic Characterization of Avian H9N2 Viruses in Southern China by Yan, Wanwan, Cui, Hongrui, Engelsma, Marc, Beerens, Nancy, van Oers, Monique M, de Jong, Mart C M, Li, Xuesong, Liu, Qinfang, Yang, Jianmei, Teng, Qiaoyang, Li, Zejun

“…The H9N2 subtype avian influenza virus (AIV) has become endemic in poultry globally; however due to its low pathogenicity, it is not under primary surveillance…”
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An Emerging Duck Egg-Reducing Syndrome Caused by a Novel Picornavirus Containing Seven Putative 2A Peptides by Su, Xin, Shuo, Dun, Luo, Yanqiu, Pan, Xue, Yan, Dawei, Li, Xuesong, Lin, Weishan, Huang, Dongming, Yang, Jianmei, Yuan, Chunxiu, Liu, Qinfang, Teng, Qiaoyang, Li, Zejun

“…Since 2016, frequent outbreaks of egg-reducing syndromes caused by an unknown virus in duck farms have resulted in huge economic losses in China. The causative…”
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