Search Results - "QI, HANMEI"

Glucocorticoids transcriptionally regulate miR-27b expression promoting body fat accumulation via suppressing the browning of white adipose tissue by Kong, Xiaocen, Yu, Jing, Bi, Jianhua, Qi, Hanmei, Di, Wenjuan, Wu, Lin, Wang, Long, Zha, Juanmin, Lv, Shan, Zhang, Feng, Li, Yan, Hu, Fang, Liu, Feng, Zhou, Hong, Liu, Juan, Ding, Guoxian

“…Long-term glucocorticoid (GC) treatment induces central fat accumulation and metabolic dysfunction. We demonstrate that microRNA-27b (miR-27b) plays a central…”
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Muscle Strength, but Not Muscle Mass, Is Associated with Left Ventricular Diastolic Function during Aging in Chinese by Pang, Sisi, Qi, Hanmei, Chen, Shu, Liu, Jin, Sheng, Yunlu

“…Sarcopenia, a progressive and systemic skeletal muscle disorder, is closely related with the incidence of cardiovascular disease (CVD) and CVD-related…”
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Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China by Chen, Lei, Sheng, Yunlu, Qi, Hanmei, Tang, Tingting, Yu, Jing, Lv, Shan

“…ObjectiveWhether sarcopenia is detrimental to depression is still controversial, which may be due to the three components of the sarcopenia. Our objective was…”
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Core Outcome Set for Clinical Trials on Coronavirus Disease 2019 (COS-COVID) by Jin, Xinyao, Pang, Bo, Zhang, Junhua, Liu, Qingquan, Yang, Zhongqi, Feng, Jihong, Liu, Xuezheng, Zhang, Lei, Wang, Baohe, Huang, Yuhong, Josephine Fauci, Alice, Ma, Yuling, Soo Lee, Myeong, Yuan, Wei'an, Xie, Yanming, Tang, Jianyuan, Gao, Rui, Du, Liang, Zhang, Shuo, Qi, Hanmei, Sun, Yu, Zheng, Wenke, Yang, Fengwen, Chua, Huizi, Wang, Keyi, Ou, Yi, Huang, Ming, Zhu, Yan, Yu, Jiajie, Tian, Jinhui, Zhao, Min, Hu, Jingqing, Yao, Chen, Li, Youping, Zhang, Boli

“…Since its outbreak in December 2019, a series of clinical trials on coronavirus disease 2019 (COVID-19) have been registered or carried out. However, the…”
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BVT.2733, a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, attenuates obesity and inflammation in diet-induced obese mice by Wang, Long, Liu, Juan, Zhang, Aisen, Cheng, Peng, Zhang, Xiao, Lv, Shan, Wu, Lin, Yu, Jing, Di, Wenjuan, Zha, Juanmin, Kong, Xiaocen, Qi, Hanmei, Zhong, Yi, Ding, Guoxian

“…Inhibition of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is being pursued as a new therapeutic approach for the treatment of obesity and metabolic…”
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Association of Mild Cognitive Impairment and Muscle Mass/Strength in Community-Dwelling Older Chinese by Jing Yu, Tingting Bi, Yunlu Sheng, Shu Chen, Aisen Zhang, Hanmei Qi, Guoxian Ding, Rong Lv, Bin Lai

“…Background: This study elucidated the association between mild cognitive impairment (MCI) and muscle mass/strength in community-dwelling older Chinese…”
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11β-hydroxysteroid dehydrogenase type 1 selective inhibitor BVT.2733 protects osteoblasts against endogenous glucocorticoid induced dysfunction by Wu, Lin, Qi, Hanmei, Zhong, Yi, Lv, Shan, Yu, Jing, Liu, Juan, Wang, Long, Bi, Jianhua, Kong, Xiaocen, Di, Wenjuan, Zha, Juanmin, Liu, Feng, Ding, Guoxian

“…Pharmacologic glucocorticoids (GCs) inhibit osteoblast function and induce osteoporosis. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) may play a role in…”
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Association of polymorphism of DNA repair gene XRCC1 with sporadic late-onset Alzheimer's disease and age of onset in elderly Han Chinese by Qian, Yun, Chen, Weixian, Wu, Jianqing, Tao, Tong, Bi, Liqing, Xu, Wei, Qi, Hanmei, Wang, Yan, Guo, Liwei

“…Abstract Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques, neurofibrillary tangles and extensive neuronal loss. There is evidence…”
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Adipose tissue-targeted 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against diet-induced obesity by Liu, Juan, Wang, Long, Zhang, Aisen, Di, Wenjuan, Zhang, Xiao, Wu, Lin, Yu, Jing, Zha, Juanmin, Lv, Shan, Cheng, Peng, Hu, Miao, Li, Yujie, Qi, Hanmei, Ding, Guoxian, Zhong, Yi

“…Current pharmacological treatments for obesity and metabolic syndrome have various limitations. Recently, adipose tissue 11β-hydroxysteroid dehydrogenase type…”
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11β-hydroxysteroid dehydrogenase type 1 selective inhibitor BVT.2733 protects osteoblasts against endogenous glucocorticoid induced dysfunction by Lin Wu, Hanmei Qi, Yi Zhong, Shan Lv, Jing Yu, Juan Liu, Long Wang, Jianhua Bi, Xiaocen Kong, Wenjuan Di, Juanmin Zha, Feng Liu, Guoxian Ding

“…[Abstract. ] Pharmacologic glucocorticoids (GCs) inhibit osteoblast function and induce osteoporosis. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) may…”
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Adipose tissue-targeted 11.BETA.-hydroxysteroid dehydrogenase type 1 inhibitor protects against diet-induced obesity by Liu, Juan, Wang, Long, Zhang, Aisen, Di, Wenjuan, Zhang, Xiao, Wu, Lin, Yu, Jing, Zha, Juanmin, Lv, Shan, Cheng, Peng, Hu, Miao, Li, Yujie, Qi, Hanmei, Ding, Guoxian, Zhong, Yi

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Opposing effects on cardiac function by calorie restriction in different‐aged mice by Sheng, Yunlu, Lv, Shan, Huang, Min, Lv, Yifan, Yu, Jing, Liu, Juan, Tang, Tingting, Qi, Hanmei, Di, Wenjuan, Ding, Guoxian

“…Summary Calorie restriction (CR) increases average and maximum lifespan and exhibits an apparent beneficial impact on age‐related diseases. Several studies…”
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Association of thyroid function with sarcopenia in elderly Chinese euthyroid subjects by Sheng, Yunlu, Ma, Dan, Zhou, Qi, Wang, Li, Sun, Minne, Wang, Siting, Qi, Hanmei, Liu, Jin, Ding, Guoxian, Duan, Yu

“…Objectives With the increase in aging population worldwide, the incidence of sarcopenia is also increasing. Thyroid hormones are important regulators that can…”
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Bone mineral density and trabecular bone score in Chinese subjects with sarcopenia by Qi, Hanmei, Sheng, Yunlu, Chen, Shu, Wang, Siting, Zhang, Aisen, Cai, Jinmei, Lai, Bing, Ding, Guoxian

“…Background As the general population is aging worldwide, the incidence of sarcopenia and osteoporosis is also rapidly increasing. Studies have found the link…”
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11β-hydroxysteroid dehydrogenase type 1 inhibitor attenuates high-fat diet induced cardiomyopathy by Huang, Min, Liu, Juan, Sheng, Yunlu, Lv, Yifan, Yu, Jing, Qi, Hanmei, Di, Wenjuan, Lv, Shan, Zhou, Suming, Ding, Guoxian

“…High-fat diet (HFD) induces cardiac hypertrophy; however, the underlying cellular and molecular mechanisms are yet unclear. In the present study, we…”
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Assessment of Fat distribution and Bone quality with Trabecular Bone Score (TBS) in Healthy Chinese Men by Lv, Shan, Zhang, Aisen, Di, Wenjuan, Sheng, Yunlu, Cheng, Peng, Qi, Hanmei, Liu, Juan, Yu, Jing, Ding, Guoxian, Cai, Jinmei, Lai, Bin

“…Whether fat is beneficial or detrimental to bones is still controversial, which may be due to inequivalence of the fat mass. Our objective is to define the…”
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MiR‐27b‐3p Regulation in Browning of Human Visceral Adipose Related to Central Obesity by Yu, Jing, Lv, Yifan, Di, Wenjuan, Liu, Juan, Kong, Xiaocen, Sheng, Yunlu, Huang, Min, Lv, Shan, Qi, Hanmei, Gao, Mei, Liang, Hui, Kim, Sarah, Fu, Zan, Zhou, Hong, Ding, Guoxian

“…Objective Given the rising prevalence of central obesity and the discovery that beige cells appear within white adipose tissue, strategies to enhance these…”
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Age-Related Changes in Trabecular Bone Score and Bone Mineral Density in Chinese Men: A Cross-Sectional and Longitudinal Study by Tang, Huan, Di, Wenjuan, Qi, Hanmei, Liu, Juan, Yu, Jing, Cai, Jinmei, Lai, Bing, Ding, Guoxian, Cheng, Peng

“…This study was designed to explore age-related changes in trabecular bone score (TBS) and bone mineral density (BMD) in Chinese men through cross-sectional and…”
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The correlation of muscle thickness and pennation angle assessed by ultrasound with sarcopenia in elderly Chinese community dwellers by Zhu, Siping, Lin, Wei, Chen, Shu, Qi, Hanmei, Wang, Siting, Zhang, Aisen, Cai, Jinmei, Lai, Bing, Sheng, Yunlu, Ding, Guoxian

“…Sarcopenia is typically defined as the loss of muscle mass, strength and low physical performance with aging. Ultrasound is a safe and easy method for…”
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Correlation of obesity and osteoporosis: Effect of free fatty acids on bone marrow-derived mesenchymal stem cell differentiation by LV, SHAN, WU, LIN, CHENG, PENG, YU, JING, ZHANG, AISEN, ZHA, JUANMIN, LIU, JUAN, WANG, LONG, DI, WENJUAN, HU, MIAO, QI, HANMEI, LI, YUJIE, DING, GUOXIAN

“…Studies on the relationship between obesity and bone have recently become widespread. The aim of this study was to investigate the effect of obesity on bone,…”
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