Search Results - "Pyz, Elwira"

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors by Dennehy, Kevin M, Ferwerda, Gerben, Faro-Trindade, Inês, Pyż, Elwira, Willment, Janet A, Taylor, Philip R, Kerrigan, Ann, Tsoni, S. Vicky, Gordon, Siamon, Meyer-Wentrup, Friederike, Adema, Gosse J, Kullberg, Bart-Jan, Schweighoffer, Edina, Tybulewicz, Victor, Mora-Montes, Hector M, Gow, Neil A.R, Williams, David L, Netea, Mihai G, Brown, Gordon D

“…Recognition of microbial components by germ-line encoded pattern recognition receptors (PRR) initiates immune responses to infectious agents. We and others…”
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Characterization of a Bispecific FLT3 X CD3 Antibody in an Improved, Recombinant Format for the Treatment of Leukemia by Durben, Michael, Schmiedel, Dominik, Hofmann, Martin, Vogt, Fabian, Nübling, Tina, Pyz, Elwira, Bühring, Hans-Jörg, Rammensee, Hans-Georg, Salih, Helmut R, Große-Hovest, Ludger, Jung, Gundram

“…FLT3 is a receptor-tyrosine-kinase that is expressed on leukemic cells of the myeloid and lymphoid lineage rather specifically. We here report on the…”
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C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers by Rizzu, Patrizia, Blauwendraat, Cornelis, Heetveld, Sasja, Lynes, Emily M, Castillo-Lizardo, Melissa, Dhingra, Ashutosh, Pyz, Elwira, Hobert, Markus, Synofzik, Matthis, Simón-Sánchez, Javier, Francescatto, Margherita, Heutink, Peter

“…A non-coding hexanucleotide repeat expansion (HRE) in C9orf72 is a common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) acting…”
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Screening for ligands of C-type lectin-like receptors by Pyż, Elwira, Brown, Gordon D

“…In order to execute their immune functions, leukocytes interact with a broad range of cell types through cell surface receptors, such as those of the…”
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Direct identification of rat iNKT cells reveals remarkable similarities to human iNKT cells and a profound deficiency in LEW rats by Monzon‐Casanova, Elisa, Paletta, Daniel, Starick, Lisa, Müller, Ingrid, Sant'Angelo, Derek B., Pyz, Elwira, Herrmann, Thomas

“…iNKT cells are a particular lymphocyte population with potent immunomodulatory capa‐city; by promoting or suppressing immune responses against infections,…”
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Human MICL (CLEC12A) is differentially glycosylated and is down‐regulated following cellular activation by Marshall, Andrew S. J., Willment, Janet A., Pyż, Elwira, Dennehy, Kevin M., Reid, Delyth M., Dri, Pietro, Gordon, Siamon, Wong, Simon Y. C., Brown, Gordon D.

“…C‐type lectins are the most diverse and prevalent lectin family in immunity. Particular interest has recently been attracted by the C‐type lectin‐like…”
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Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand by Pyż, Elwira, Huysamen, Cristal, Marshall, Andrew S.J, Gordon, Siamon, Taylor, Philip R, Brown, Gordon D

“…Inhibitory receptors are required for the control of cellular activation and they play essential roles in regulating homeostasis and immunity. We previously…”
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The Complementarity Determining Region 2 of BV8S2 (Vbeta8.2) Contributes to Antigen Recognition by Rat Invariant NKT Cell TCR by Pyz, Elwira, Naidenko, Olga, Miyake, Sachiko, Yamamura, Takashi, Berberich, Ingolf, Cardell, Susanna, Kronenberg, Mitchell, Herrmann, Thomas

“…Invariant NKT cells (iNKT cells) are characterized by a semi-invariant TCR comprising an invariant alpha-chain paired with beta-chains with limited BV gene…”
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CD1d expression in paneth cells and rat exocrine pancreas revealed by novel monoclonal antibodies which differentially affect NKT cell activation by Monzon-Casanova, Elisa, Steiniger, Birte, Schweigle, Stefanie, Clemen, Holger, Zdzieblo, Daniela, Starick, Lisa, Müller, Ingrid, Wang, Chyung-Ru, Rhost, Sara, Cardell, Susanna, Pyz, Elwira, Herrmann, Thomas

“…CD1d is a nonpolymorphic MHC class I-like molecule which presents nonpeptide ligands, e.g. glycolipids, to NKT cells. These cells are known to have multiple…”
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C-type lectin-like receptors on myeloid cells by Pyz, Elwira, Marshall, Andrew S J, Gordon, Siamon, Brown, Gordon D

“…Host defence against pathogens requires the recognition of conserved microbial molecules, or 'pathogen-associated molecular patterns' (PAMPs), by their…”
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Reduction of Minimal Residual Disease in Pediatric B-lineage Acute Lymphoblastic Leukemia by an Fc-optimized CD19 Antibody by Seidel, Ursula Jördis Eva, Schlegel, Patrick, Grosse-Hovest, Ludger, Hofmann, Martin, Aulwurm, Steffen, Pyz, Elwira, Schuster, Friedhelm R, Meisel, Roland, Ebinger, Martin, Feuchtinger, Tobias, Teltschik, Heiko-Manuel, Witte, Kai-Erik, Schwarze, Carl-Philipp, Rammensee, Hans-Georg, Handgretinger, Rupert, Jung, Gundram, Lang, Peter

“…Prognosis of primary refractory and relapsed pediatric B-lineage acute lymphoblastic leukemia (ALL) is very poor. Relapse rates significantly correlate with…”
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From Bedside To Bench: Molecular Benchmarking Of An Fc-Optimized CD19 Antibody Used In Treatment Of Relapsed and Refractory Pediatric B-Lineage Acute Lymphoblastic Leukemia by Seidel, Ursula J.E., Grosse-Hovest, Ludger, Schlegel, Patrick, Hofmann, Martin, Schuster, Friedhelm R., Witte, Kai-Erik, Aulwurm, Steffen, Teltschik, Rouwen, Pyz, Elwira, Rammensee, Hans-Georg, Jung, Gundram, Handgretinger, Rupert, Lang, Peter

“…B-lineage acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Although this disease can be curatively treated in 80% of patients by…”
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