Search Results - "Pynka, M"
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Long‐term trends in HIV care entry: over 15 years of clinical experience from Poland
Published in HIV medicine (01-10-2019)“…Introduction Delay in HIV diagnosis and consequently late care entry with low CD4 counts remain a major challenge for the control of the HIV/AIDS epidemic. The…”
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Association of chemokine receptor gene variants with HIV‐1 genotype predicted tropism
Published in HIV medicine (01-11-2014)“…Objectives As a switch from chemokine (C‐C motif) receptor 5 [CCR5 (R5)] to chemokine (C‐X‐C motif) receptor 4 [CXCR4 (X4)] HIV‐1 tropism is associated with…”
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Introduction of pharmacogenetic screening for the human leucocyte antigen (HLA) B5701 variant in Polish HIV‐infected patients
Published in HIV medicine (01-05-2010)“…Objective Prospective pharmacogenetic screening for the human leucocyte antigen (HLA) B*5701 allele can significantly reduce the number of cases of…”
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Integrase resistance variants among integrase inhibitor treatment‐naïve and treated patients from Northwestern Poland
Published in Journal of the International AIDS Society (01-11-2012)“…Purpose of the study HIV integrase inhibitor use is limited by low genetic barrier to resistance and possible cross‐resistance among representatives of the…”
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CCR5 D32 modifies 15‐year mortality risk associated with well‐established clinical and immunological factors among HIV‐infected patients
Published in Journal of the International AIDS Society (01-11-2010)“…7‐11 November 2010, Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK…”
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Sequence variants of chemokine receptor genes and susceptibility to HIV-1 infection
Published in Journal of applied genetics (01-01-2009)“…Genetic susceptibility to HIV infection was previously proven to be influenced by some chemokine receptor polymorphisms clustering on chromosome 3p21. Here the…”
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Opportunistic infections and other AIDS-defining illnesses in Poland in 2000-2002
Published in Infection (01-08-2006)“…The introduction of highly active antiretroviral therapy (HAART) led to a decreased incidence of the most severe opportunistic infections (OIs) in HIV-infected…”
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HIV-1 drug resistance patterns among treatment-naïve and therapy-experienced patients in Poland
Published in HIV & AIDS review (2007)“…Summary Background HIV-1 drug resistance (DR) is becoming a growing concern. It is estimated that about one out of ten newly HIV-infected persons in Europe…”
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Infection‐related and ‐unrelated malignancies, HIV and the aging population
Published in HIV medicine (01-09-2016)“…Objectives HIV‐positive people have increased risk of infection‐related malignancies (IRMs) and infection‐unrelated malignancies (IURMs). The aim of the study…”
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Disseminated infection with Saccharomyces kluyveri in a patient with AIDS
Published in Infection (01-05-1998)“…A 47-year-old man with acquired immune deficiency syndrome was found to have disseminated Saccharomyces kluyveri infection. The yeast was isolated from blood…”
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Disseminated infection withSaccharomyces kluyveri in a patient with AIDS
Published in Infection (01-05-1998)“…A 47-year-old man with acquired immune deficiency syndrome was found to have disseminatedSaccharomyces kluyveri infection. The yeast was isolated from blood…”
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Regional differences in AIDS and non-AIDS related mortality in HIV-positive individuals across Europe and Argentina: the EuroSIDA study
Published in PloS one (23-07-2012)“…Differences in access to care and treatment have been reported in Eastern Europe, a region with one of the fastest growing HIV epidemics, compared to the rest…”
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IL28B CC genotype is associated with higher all-cause mortality in antiretroviral-treated HIV-infected patients
Published in AIDS research and human retroviruses (01-12-2012)“…Il28B single nucleotide polymorphisms were found to influence interferon λ expression, resulting in changes in hepatitis C virus (HCV)-RNA serum levels as well…”
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Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA study
Published in HIV medicine (01-07-2003)“…Objectives To describe the prevalence and risk factors of poor CD4 count rise despite a good virological response on highly active antiretroviral treatment…”
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Thymidine analogue mutation profiles : factors associated with acquiring specific profiles and their impact on the virological response to therapy
Published in Antiviral therapy (01-01-2005)“…Studies have suggested that HIV-1 may develop thymidine analogue mutations (TAMs) by one of two distinct pathways - the TAM1 pathway (including mutations 41L,…”
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Changes in hospital admissions across Europe: 1995–2003. Results from the EuroSIDA study
Published in HIV medicine (01-11-2004)“…Objectives To describe changes in the proportions of patients admitted to hospital and the duration of admission during the month of March between 1995 and…”
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Are specific antiretrovirals associated with an increased risk of discontinuation due to toxicities or patient/physician choice in patients with hepatitis C virus coinfection?
Published in Antiviral therapy (01-01-2005)“…Liver damage associated with hepatitis C (HCV) may influence the likelihood of experiencing discontinuation due to toxicities or patient/physician choice…”
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Response to antiretroviral therapy among patients exposed to three classes of antiretrovirals: results from the EuroSIDA study
Published in Antiviral therapy (01-03-2002)“…There is an increasing proportion of HIV-positive patients exposed to all licensed classes of antiretrovirals, and the response to salvage regimens may be…”
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Baseline resistance and virological outcome in patients with virological failure who start a regimen containing abacavir: EuroSIDA study
Published in Antiviral therapy (01-10-2004)“…To investigate the ability of several HIV-1 drug-resistance interpretation systems, as well as the number of pre-specified combinations of abacavir-related…”
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Natural cytotoxicity of peripheral blood mononuclear cells in Herpes simplex and Varicella-zoster virus infections
Published in Acta haematologica polonica (1995)“…Natural cytotoxicity of peripheral blood was assessed in adults with recurrent Herpes labialis and in patients with Herpes zoster. CD16+ cells count,…”
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