Search Results - "Pyne, Alice L.B."

Biomimetic Hybrid Nanocontainers with Selective Permeability by Messager, Lea, Burns, Jonathan R., Kim, Jungyeon, Cecchin, Denis, Hindley, James, Pyne, Alice L. B., Gaitzsch, Jens, Battaglia, Giuseppe, Howorka, Stefan

“…Chemistry plays a crucial role in creating synthetic analogues of biomacromolecular structures. Of particular scientific and technological interest are…”
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TopoStats – A program for automated tracing of biomolecules from AFM images by Beton, Joseph G., Moorehead, Robert, Helfmann, Luzie, Gray, Robert, Hoogenboom, Bart W., Joseph, Agnel Praveen, Topf, Maya, Pyne, Alice L.B.

“…•TopoStats is a Python toolkit for automated AFM data processing.•TopoStats takes raw data as input, and outputs processed data and statistical information…”
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Imaging the Effects of Peptide Materials on Phospholipid Membranes by Atomic Force Microscopy by Hammond, Katharine, Benn, Georgina, Bennett, Isabel, Parsons, Edward S, Ryadnov, Maxim G, Hoogenboom, Bart W, Pyne, Alice L B

“…Recent advances in biomolecular design require accurate measurements performed in native or near-native environments in real time. Atomic force microscopy…”
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Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms by Pfeil, Marc-Philipp, Pyne, Alice L. B., Losasso, Valeria, Ravi, Jascindra, Lamarre, Baptiste, Faruqui, Nilofar, Alkassem, Hasan, Hammond, Katharine, Judge, Peter J., Winn, Martyn, Martyna, Glenn J., Crain, Jason, Watts, Anthony, Hoogenboom, Bart W., Ryadnov, Maxim G.

“…The spread of antimicrobial resistance stimulates discovery strategies that place emphasis on mechanisms circumventing the drawbacks of traditional antibiotics…”
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Imaging DNA Structure by Atomic Force Microscopy by Pyne, Alice L B, Hoogenboom, Bart W

“…Atomic force microscopy (AFM) is a microscopy technique that uses a sharp probe to trace a sample surface at nanometre resolution. For biological applications,…”
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Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides by Pyne, Alice L. B., Noy, Agnes, Main, Kavit H. S., Velasco-Berrelleza, Victor, Piperakis, Michael M., Mitchenall, Lesley A., Cugliandolo, Fiorella M., Beton, Joseph G., Stevenson, Clare E. M., Hoogenboom, Bart W., Bates, Andrew D., Maxwell, Anthony, Harris, Sarah A.

“…In the cell, DNA is arranged into highly-organised and topologically-constrained (supercoiled) structures. It remains unclear how this supercoiling affects the…”
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Single-molecule kinetics of pore assembly by the membrane attack complex by Parsons, Edward S., Stanley, George J., Pyne, Alice L. B., Hodel, Adrian W., Nievergelt, Adrian P., Menny, Anaïs, Yon, Alexander R., Rowley, Ashlea, Richter, Ralf P., Fantner, Georg E., Bubeck, Doryen, Hoogenboom, Bart W.

“…The membrane attack complex (MAC) is a hetero-oligomeric protein assembly that kills pathogens by perforating their cell envelopes. The MAC is formed by…”
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Direct observation of Shelterin dynamics and T-loop formation at telomeres by Newton, Matthew D., Lewis, Jacob S., Anand, Roopesh, Holmes, Elizabeth P., Pyne, Alice L.B., Boulton, Simon J.

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Bacterial killing by complement requires membrane attack complex formation via surface‐bound C5 convertases by Heesterbeek, Dani AC, Bardoel, Bart W, Parsons, Edward S, Bennett, Isabel, Ruyken, Maartje, Doorduijn, Dennis J, Gorham, Ronald D, Berends, Evelien TM, Pyne, Alice LB, Hoogenboom, Bart W, Rooijakkers, Suzan HM

“…The immune system kills bacteria by the formation of lytic membrane attack complexes (MACs), triggered when complement enzymes cleave C5. At present, it is not…”
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Imaging live bacteria at the nanoscale: comparison of immobilisation strategies by Benn, Georgina, Pyne, Alice L B, Ryadnov, Maxim G, Hoogenboom, Bart W

“…Atomic force microscopy (AFM) provides an effective, label-free technique enabling the imaging of live bacteria under physiological conditions with nanometre…”
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PEGylated surfaces for the study of DNA-protein interactions by atomic force microscopy by Akpinar, Bernice, Haynes, Philip J, Bell, Nicholas A W, Brunner, Katharina, Pyne, Alice L B, Hoogenboom, Bart W

“…DNA-protein interactions are vital to cellular function, with key roles in the regulation of gene expression and genome maintenance. Atomic force microscopy…”
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Cantilever Sensors for Rapid Optical Antimicrobial Sensitivity Testing by Bennett, Isabel, Pyne, Alice L. B, McKendry, Rachel A

“…Growing antimicrobial resistance (AMR) is a serious global threat to human health. Current methods to detect resistance include phenotypic antibiotic…”
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Autophagy receptor NDP52 alters DNA conformation to modulate RNA polymerase II transcription by dos Santos, Ália, Rollins, Daniel E., Hari-Gupta, Yukti, McArthur, Hannah, Du, Mingxue, Ru, Sabrina Yong Zi, Pidlisna, Kseniia, Stranger, Ane, Lorgat, Faeeza, Lambert, Danielle, Brown, Ian, Howland, Kevin, Aaron, Jesse, Wang, Lin, Ellis, Peter J. I., Chew, Teng-Leong, Martin-Fernandez, Marisa, Pyne, Alice L. B., Toseland, Christopher P.

“…NDP52 is an autophagy receptor involved in the recognition and degradation of invading pathogens and damaged organelles. Although NDP52 was first identified in…”
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Atomic force microscopy—A tool for structural and translational DNA research by Main, Kavit H. S., Provan, James I., Haynes, Philip J., Wells, Geoffrey, Hartley, John A., Pyne, Alice L. B.

“…Atomic force microscopy (AFM) is a powerful imaging technique that allows for structural characterization of single biomolecules with nanoscale resolution. AFM…”
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DNA Origami Inside-Out Viruses by Burns, Jonathan R, Lamarre, Baptiste, Pyne, Alice L. B, Noble, James E, Ryadnov, Maxim G

“…A synthetic topology for everted viruses is reported. The topology is a single-stranded virion DNA assembled into a hollow cube with exterior decorated with…”
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Studies of G-quadruplexes formed within self-assembled DNA mini-circles by Klejevskaja, Beata, Pyne, Alice L B, Reynolds, Matthew, Shivalingam, Arun, Thorogate, Richard, Hoogenboom, Bart W, Ying, Liming, Vilar, Ramon

“…We have developed self-assembled DNA mini-circles that contain a G-quadruplex-forming sequence from the c-Myc oncogene promoter and demonstrate by FRET that…”
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