Search Results - "Pyle, Meredith E"
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Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease
Published in Blood (01-11-2012)“…Sickle cell disease is a common hemolytic disorder with a broad range of complications, including vaso-occlusive episodes, acute chest syndrome (ACS), pain,…”
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Magnetic resonance angiography-defined intracranial vasculopathy is associated with silent cerebral infarcts and glucose-6-phosphate dehydrogenase mutation in children with sickle cell anaemia
Published in British journal of haematology (01-11-2012)“…Summary Silent cerebral infarct (SCI) is the most commonly recognized cause of neurological injury in sickle cell anaemia (SCA). We tested the hypothesis that…”
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Whole blood gene expression profiles distinguish clinical phenotypes of venous thromboembolism
Published in Thrombosis research (01-04-2015)“…Abstract Introduction Recurrent venous thromboembolism (VTE) occurs infrequently following a provoked event but occurs in up to 30% of individuals following an…”
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Acute chest syndrome is associated with single nucleotide polymorphism‐defined beta globin cluster haplotype in children with sickle cell anaemia
Published in British journal of haematology (01-10-2013)“…Summary Genetic diversity at the human β‐globin locus has been implicated as a modifier of sickle cell anaemia (SCA) severity. However, haplotypes defined by…”
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