Search Results - "Pyle, Marla"

Naïve human umbilical cord matrix derived stem cells significantly attenuate growth of human breast cancer cells in vitro and in vivo by Ayuzawa, Rie, Doi, Chiyo, Rachakatla, Raja Shekar, Pyle, Marla M, Maurya, Dharmendra Kumar, Troyer, Deryl, Tamura, Masaaki

“…Abstract The effect of un-engineered (naïve) human umbilical cord matrix stem cells (hUCMSC) on the metastatic growth of MDA 231 xenografts in SCID mouse lung…”
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A/C magnetic hyperthermia of melanoma mediated by iron(0)/iron oxide core/shell magnetic nanoparticles: a mouse study by Balivada, Sivasai, Rachakatla, Raja Shekar, Wang, Hongwang, Samarakoon, Thilani N, Dani, Raj Kumar, Pyle, Marla, Kroh, Franklin O, Walker, Brandon, Leaym, Xiaoxuan, Koper, Olga B, Tamura, Masaaki, Chikan, Viktor, Bossmann, Stefan H, Troyer, Deryl L

“…There is renewed interest in magnetic hyperthermia as a treatment modality for cancer, especially when it is combined with other more traditional therapeutic…”
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In Vitro Measurement and Mathematical Modeling of Thermally-Induced Injury in Pancreatic Cancer Cells by Chamani, Faraz, Pyle, Marla M, Shrestha, Tej B, Sebek, Jan, Bossmann, Stefan H, Basel, Matthew T, Sheth, Rahul A, Prakash, Punit

“…Thermal therapies are under investigation as part of multi-modality strategies for the treatment of pancreatic cancer. In the present study, we determined the…”
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System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance by Sebek, Jan, Shrestha, Tej B., Basel, Matthew T., Chamani, Faraz, Zeinali, Nooshin, Mali, Ivina, Payne, Macy, Timmerman, Sarah A., Faridi, Pegah, Pyle, Marla, O'Halloran, Martin, Dennedy, M. Conall, Bossmann, Stefan H., Prakash, Punit

“…Bio-effects following thermal treatments are a function of the achieved temperature profile in tissue, which can be estimated across tumor volumes with…”
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An integrated platform for small-animal hyperthermia investigations under ultra-high-field MRI guidance by Curto, Sergio, Faridi, Pegah, Shrestha, Tej B, Pyle, Marla, Maurmann, Leila, Troyer, Deryl, Bossmann, Stefan H, Prakash, Punit

“…Integrating small-animal experimental hyperthermia instrumentation with magnetic resonance imaging (MRI) affords real-time monitoring of spatial temperature…”
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Therapy with un-engineered naïve rat umbilical cord matrix stem cells markedly inhibits growth of murine lung adenocarcinoma by Maurya, Dharmendra K, Doi, Chiyo, Kawabata, Atsushi, Pyle, Marla M, King, Clay, Wu, Zhihong, Troyer, Deryl, Tamura, Masaaki

“…Lung cancer remains the leading cause of cancer-related mortality despite continuous efforts to find effective treatments. Data from the American Cancer…”
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Human umbilical cord matrix-derived stem cells expressing interferon-β gene significantly attenuate bronchioloalveolar carcinoma xenografts in SCID mice by Matsuzuka, Takaya, Rachakatla, Raja Shekar, Doi, Chiyo, Maurya, Dharmendra Kumar, Ohta, Naomi, Kawabata, Atsushi, Pyle, Marla M, Pickel, Lara, Reischman, Jennifer, Marini, Frank, Troyer, Deryl, Tamura, Masaaki

“…Abstract Mesenchymal stem cells derived from the human umbilical cord matrix (hUCMSCs) have great potential for therapeutic use for multiple diseases. The…”
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Human umbilical cord matrix mesenchymal stem cells suppress the growth of breast cancer by expression of tumor suppressor genes by Ohta, Naomi, Ishiguro, Susumu, Kawabata, Atsushi, Uppalapati, Deepthi, Pyle, Marla, Troyer, Deryl, De, Supriyo, Zhang, Yongqing, Becker, Kevin G, Tamura, Masaaki

“…Human and rat umbilical cord matrix mesenchymal stem cells (UCMSC) possess the ability to control the growth of breast carcinoma cells. Comparative analyses of…”
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A Cell-Delivered and Cell-Activated SN38-Dextran Prodrug Increases Survival in a Murine Disseminated Pancreatic Cancer Model by Basel, Matthew T., Balivada, Sivasai, Shrestha, Tej B., Seo, Gwi-Moon, Pyle, Marla M., Tamura, Masaaki, Bossmann, Stefan H., Troyer, Deryl L.

“…Enzyme‐activated prodrugs have been investigated and sought after as highly specific, low‐side‐effect treatments, especially for cancer therapy. Unfortunately,…”
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Cytotherapy with naive rat umbilical cord matrix stem cells significantly attenuates growth of murine pancreatic cancer cells and increases survival in syngeneic mice by Doi, Chiyo, Maurya, Dharmendra Kumar, Pyle, Marla M, Troyer, Deryl, Tamura, Masaaki

“…Abstract Background aims Pancreatic cancer, sometimes called a ‘silent killer’, is one of the most aggressive human malignancies, with a very poor prognosis…”
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Magnetic-Fe/Fe3O4-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages by Wang, Hongwang, Shrestha, Tej B, Basel, Matthew T, Dani, Raj Kumar, Seo, Gwi-Moon, Balivada, Sivasai, Pyle, Marla M, Prock, Heidy, Koper, Olga B, Thapa, Prem S, Moore, David, Li, Ping, Chikan, Viktor, Troyer, Deryl L, Bossmann, Stefan H

“…The targeted delivery of therapeutics to the tumor site is highly desirable in cancer treatment, because it is capable of minimizing collateral damage. Herein,…”
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Luminol-based bioluminescence imaging of mouse mammary tumors by Alshetaiwi, Hamad S., Balivada, Sivasai, Shrestha, Tej B., Pyle, Marla, Basel, Matthew T., Bossmann, Stefan H., Troyer, Deryl L.

“…[Display omitted] •Luminol can be used to track neutrophil invasion of tumors.•For the first time, we have shown Luminol can be used to image solid carcinomas…”
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Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses by Kawabata, Atsushi, Ohta, Naomi, Seiler, Garret, Pyle, Marla M, Ishiguro, Susumu, Zhang, Yong Qing, Becker, Kevin G, Troyer, Deryl, Tamura, Masaaki

“…Abstract Background aims Un-engineered human and rat umbilical cord matrix stem cells (UCMSCs) attenuate growth of several types of tumors in mice and rats…”
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Designing a Cleavable Cell Surface Protein for Cytotherapy and Drug Delivery Applications by Basel, Matthew T., Shrestha, Tej B., Pyle, Marla, Nguyen, Tuyen Duong Thanh, Aryal, Santosh, Troyer, Deryl L., Bossmann, Stefan H.

“…Many cytotherapy applications focus on delivering a therapeutic molecule or nanoparticle to a disease site. One challenging step in this delivery is releasing…”
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Combination Treatment of Human Umbilical Cord Matrix Stem Cell-Based Interferon-Beta Gene Therapy and 5-Fluorouracil Significantly Reduces Growth of Metastatic Human Breast Cancer in SCID Mouse Lungs by Rachakatla, Raja Shekar, Pyle, Marla M., Ayuzawa, Rie, Edwards, Sarah M., Marini, Frank C., Weiss, Mark L., Tamura, Masaaki, Troyer, Deryl

“…Umbilical cord matrix stem (UCMS) cells that were engineered to express interferon-beta (IFN-β) were transplanted weekly for three weeks into MDA 231 breast…”
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Identification and Characterization of Unique Tumoricidal Genes in Rat Umbilical Cord Matrix Stem Cells by Uppalapati, Deepthi, Ohta, Naomi, Zhang, Yongqing, Kawabata, Atsushi, Pyle, Marla M, Becker, Kevin G, Troyer, Deryl, Tamura, Masaaki

“…Rat umbilical cord matrix stem cells (UCMSC) have been shown to exhibit a remarkable ability to control rat mammary adenocarcinoma (Mat B III) cell…”
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Human xenografts are not rejected in a naturally occurring immunodeficient porcine line: a human tumor model in pigs by Basel, Matthew T, Balivada, Sivasai, Beck, Amanda P, Kerrigan, Maureen A, Pyle, Marla M, Dekkers, Jack C M, Wyatt, Carol R, Rowland, Robert R R, Anderson, David E, Bossmann, Stefan H, Troyer, Deryl L

“…Animal models for cancer therapy are invaluable for preclinical testing of potential cancer treatments; however, therapies tested in such models often fail to…”
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A Review of In Vitro Instrumentation Platforms for Evaluating Thermal Therapies in Experimental Cell Culture Models by Chamani, Faraz, Barnett, India, Pyle, Marla, Shrestha, Tej, Prakash, Punit

“…Thermal therapies, the modulation of tissue temperature for therapeutic benefit, are in clinical use as adjuvant or stand-alone therapeutic modalities for a…”
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Abstract 1481: Selective protein expression in tumor cells controlled by progression elevated gene-3 promoter by Pando, Ruben, Shrestha, Tej, Pyle, Marla, Troyer, Deryl

“…Abstract The progression elevated gene-3 (PEG-3) promoter is a rodent gene that has shown strong activity in tumor progression. Demonstrating tumor specificity…”
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Thermosensitive Liposomes for Gemcitabine Delivery to Pancreatic Ductal Adenocarcinoma by Aparicio-Lopez, Cesar B, Timmerman, Sarah, Lorino, Gabriella, Rogers, Tatiana, Pyle, Marla, Shrestha, Tej B, Basel, Matthew T

“…Treatment of pancreatic ductal adenocarcinoma with gemcitabine is limited by an increased desmoplasia, poor vascularization, and short plasma half-life…”
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