Search Results - "Pyae, Aung"

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study by Phyo, Aung Pyae, MD, Nkhoma, Standwell, PhD, Stepniewska, Kasia, PhD, Ashley, Elizabeth A, MD, Nair, Shalini, MSc, McGready, Rose, MD, ler Moo, Carit, Al-Saai, Salma, MSc, Dondorp, Arjen M, MD, Lwin, Khin Maung, MD, Singhasivanon, Pratap, MD, Day, Nicholas PJ, FRCP, White, Nicholas J, FRS, Anderson, Tim JC, PhD, Nosten, François, Prof

“…Summary Background Artemisinin-resistant falciparum malaria has arisen in western Cambodia. A concerted international effort is underway to contain…”
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Clinical impact of vivax malaria: A collection review by Phyo, Aung Pyae, Dahal, Prabin, Mayxay, Mayfong, Ashley, Elizabeth A

“…Plasmodium vivax infects an estimated 7 million people every year. Previously, vivax malaria was perceived as a benign condition, particularly when compared to…”
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Spiroindolone KAE609 for Falciparum and Vivax Malaria by White, Nicholas J, Pukrittayakamee, Sasithon, Phyo, Aung Pyae, Rueangweerayut, Ronnatrai, Nosten, François, Jittamala, Podjanee, Jeeyapant, Atthanee, Jain, Jay Prakash, Lefèvre, Gilbert, Li, Ruobing, Magnusson, Baldur, Diagana, Thierry T, Leong, F. Joel

“…New antimalarial agents are needed, especially given the emergence of artemisinin resistance. In this study from Thailand, treatment with KAE609, the first in…”
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Combating multidrug‐resistant Plasmodium falciparum malaria by Thu, Aung Myint, Phyo, Aung Pyae, Landier, Jordi, Parker, Daniel M., Nosten, François H.

“…Over the past 50 years, Plasmodium falciparum has developed resistance against all antimalarial drugs used against it: chloroquine, sulphadoxine–pyrimethamine,…”
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Six-month efficacy data for Cenobamate in refractory focal epilepsy – a viable alternative to VNS? by Pyae, Aung, Tom, Hayton, Barbara, Wysota, Salini, Sumangala, Shanika, Samarasekera

“…ObjectiveTo assess the efficacy of adjuvant Cenobamate in adults with refractory focal epilepsy.MethodologyA retrospective cohort study was conducted. Patients…”
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Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial by Hoglund, Richard M, Pyae Phyo, Aung, Lek, Dysoley, Anvikar, Anupkumar R, Satpathi, Parthasarathi, Satpathi, Sanghamitra, Behera, Prativa Kumari, Tripura, Amar, Baidya, Subrata, Chau, Nguyen Hoang, Sovann, Yok, Mao, Sivanna, Oun, Savuth, Yen, Sovannary, Amaratunga, Chanaki, Saelow, Chalermpon, Runcharern, Ratchadaporn, Kaewmok, Weerayuth, Hanboonkunupakarn, Borimas, Mohanty, Akshaya Kumar, Heaton, James, Thant, Myo, Gantait, Kripasindhu, Ghosh, Tarapada, Amato, Roberto, Jacob, Christopher G, Gonçalves, Sónia, Waithira, Naomi, Grobusch, Martin P, van Vugt, Michele, Fairhurst, Rick M, Cheah, Phaik Yeong, Dhorda, Mehul, Maude, Richard J, Winterberg, Markus, Thuy-Nhien, Nguyen Thanh, Kwiatkowski, Dominic P, Jittamala, Podjanee, Lin, Khin, Chotivanich, Kesinee, Huy, Rekol, Ashley, Elizabeth, Mayxay, Mayfong, Newton, Paul N, Hien, Tran Tinh, Valecha, Neena, Smithuis, Frank, Faiz, Abul, Miotto, Olivo, Tarning, Joel, Day, Nicholas P J, White, Nicholas J, van der Pluijm, Rob W, Hoglund, Richard M, Phyo, Aung Pyae, ul Islam, Akhter, Anvikar, Anupkumar R, Satpathi, Parthasarathi, Behera, Prativa Kumari, Tripura, Amar, Baidya, Subrata, Onyamboko, Marie, Chau, Nguyen Hoang, Sovann, Yok, Sreng, Sokunthea, Oun, Savuth, Amaratunga, Chanaki, Chutasmit, Kitipumi, Saelow, Chalermpon, Hoa, Nhu Thi, Thanh, Ngo Viet, Hanboonkunupakarn, Borimas, Callery, James J, Heaton, James, Thant, Myo, Gantait, Kripasindhu, Ghosh, Tarapada, Woodrow, Charles J, Grobusch, Martin P, van Vugt, Michele, Fairhurst, Rick M, Cheah, Phaik Yeong, Peto, Thomas J, von Seidlein, Lorenz, Maude, Richard J, Winterberg, Markus, Kwiatkowski, Dominic P, Imwong, Mallika, Jittamala, Podjanee, Lin, Khin, Hlaing, Tin Maung, Chotivanich, Kesinee, Ashley, Elizabeth, Newton, Paul N, Hien, Tran Tinh, Faiz, Abul, Miotto, Olivo, Tarning, Joel, Day, Nicholas PJ, Dondorp, Arjen M

“…Artemisinin and partner-drug resistance in Plasmodium falciparum are major threats to malaria control and elimination. Triple artemisinin-based combination…”
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Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent by Taylor, Aimee R, Schaffner, Stephen F, Cerqueira, Gustavo C, Nkhoma, Standwell C, Anderson, Timothy J C, Sriprawat, Kanlaya, Pyae Phyo, Aung, Nosten, François, Neafsey, Daniel E, Buckee, Caroline O

“…With the rapidly increasing abundance and accessibility of genomic data, there is a growing interest in using population genetic approaches to characterize…”
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Genetic architecture of artemisinin-resistant Plasmodium falciparum by Miotto, Olivo, Amato, Roberto, Ashley, Elizabeth A, MacInnis, Bronwyn, Almagro-Garcia, Jacob, Amaratunga, Chanaki, Lim, Pharath, Mead, Daniel, Oyola, Samuel O, Dhorda, Mehul, Imwong, Mallika, Woodrow, Charles, Manske, Magnus, Stalker, Jim, Drury, Eleanor, Campino, Susana, Amenga-Etego, Lucas, Thanh, Thuy-Nhien Nguyen, Tran, Hien Tinh, Ringwald, Pascal, Bethell, Delia, Nosten, Francois, Phyo, Aung Pyae, Pukrittayakamee, Sasithon, Chotivanich, Kesinee, Chuor, Char Meng, Nguon, Chea, Suon, Seila, Sreng, Sokunthea, Newton, Paul N, Mayxay, Mayfong, Khanthavong, Maniphone, Hongvanthong, Bouasy, Htut, Ye, Han, Kay Thwe, Kyaw, Myat Phone, Faiz, Md Abul, Fanello, Caterina I, Onyamboko, Marie, Mokuolu, Olugbenga A, Jacob, Christopher G, Takala-Harrison, Shannon, Plowe, Christopher V, Day, Nicholas P, Dondorp, Arjen M, Spencer, Chris C A, McVean, Gilean, Fairhurst, Rick M, White, Nicholas J, Kwiatkowski, Dominic P

“…Dominic Kwiatkowski and colleagues report a large multicenter genome-wide association study of Plasmodium falciparum resistance to artemisinin. They identify…”
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Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites by Anderson, Timothy J C, Nair, Shalini, McDew-White, Marina, Cheeseman, Ian H, Nkhoma, Standwell, Bilgic, Fatma, McGready, Rose, Ashley, Elizabeth, Pyae Phyo, Aung, White, Nicholas J, Nosten, François

“…Multiple kelch13 alleles conferring artemisinin resistance (ART-R) are currently spreading through Southeast Asian malaria parasite populations, providing a…”
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A Major Genome Region Underlying Artemisinin Resistance in Malaria by Cheeseman, Ian H., Miller, Becky A., Nair, Shalini, Nkhoma, Standwell, Tan, Asako, Tan, John C., Saai, Salma Al, Phyo, Aung Pyae, Moo, Carit Ler, Lwin, Khin Maung, McGready, Rose, Ashley, Elizabeth, Imwong, Mallika, Stepniewska, Kasia, Yi, Poravuth, Dondorp, Arjen M., Mayxay, Mayfong, Newton, Paul N., White, Nicholas J., Nosten, François, Ferdig, Michael T., Anderson, Timothy J. C.

“…Evolving resistance to arte misi ni n-based compounds threatens to derail attempts to control malaria. Resistance has been confirmed in western Cambodia and…”
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Plasmodium falciparum ATP4 inhibitors to treat malaria: worthy successors to artemisinin? by Ashley, Elizabeth A, Phyo, Aung Pyae

“…Progress in controlling malaria has slowed in recent years and the annual death toll remains above 400 000 globally, with most deaths caused by Plasmodium…”
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New malaria maps by Nosten, Francois H, Phyo, Aung Pyae

“…[...]the data presented are the results of complex mathematical models and do not necessarily represent the actual truth on the ground. [...]the user should…”
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Molecular epidemiology of resistance to antimalarial drugs in the Greater Mekong subregion: an observational study by Imwong, Mallika, Dhorda, Mehul, Myo Tun, Kyaw, Thu, Aung Myint, Phyo, Aung Pyae, Proux, Stephane, Suwannasin, Kanokon, Kunasol, Chanon, Srisutham, Suttipat, Duanguppama, Jureeporn, Vongpromek, Ranitha, Promnarate, Cholrawee, Saejeng, Aungkana, Khantikul, Nardlada, Sugaram, Rungniran, Thanapongpichat, Supinya, Sawangjaroen, Nongyao, Sutawong, Kreepol, Han, Kay Thwe, Htut, Ye, Linn, Khin, Win, Aye Aye, Hlaing, Tin M, van der Pluijm, Rob W, Mayxay, Mayfong, Pongvongsa, Tiengkham, Phommasone, Koukeo, Tripura, Rupam, Peto, Thomas J, von Seidlein, Lorenz, Nguon, Chea, Lek, Dysoley, Chan, Xin Hui S, Rekol, Huy, Leang, Rithea, Huch, Cheah, Kwiatkowski, Dominic P, Miotto, Olivo, Ashley, Elizabeth A, Kyaw, Myat Phone, Pukrittayakamee, Sasithon, Day, Nicholas P J, Dondorp, Arjen M, Smithuis, Frank M, Nosten, Francois H, White, Nicholas J

“…The Greater Mekong subregion is a recurrent source of antimalarial drug resistance in Plasmodium falciparum malaria. This study aimed to characterise the…”
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Phylogenomic Analysis of Ultraconserved Elements Resolves the Evolutionary and Biogeographic History of Segmented Trapdoor Spiders by Xu, Xin, Su, Yong-Chao, Ho, Simon Y W, Kuntner, Matjaž, Ono, Hirotsugu, Liu, Fengxiang, Chang, Chia-Chen, Warrit, Natapot, Sivayyapram, Varat, Aung, Khin Pyae Pyae, Pham, Dinh Sac, Norma-Rashid, Y, Li, Daiqin

“…Abstract The segmented trapdoor spiders (Liphistiidae) are the sole surviving family of the suborder Mesothelae, which forms the sister lineage to all other…”
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Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial by Phyo, Aung Pyae, MD, Jittamala, Podjanee, MD, Nosten, François H, Prof, Pukrittayakamee, Sasithon, Prof, Imwong, Mallika, PhD, White, Nicholas J, Prof, Duparc, Stephan, MD, Macintyre, Fiona, PhD, Baker, Mark, PhD, Möhrle, Jörg J, Dr

“…Summary Background Artefenomel (OZ439) is a novel synthetic trioxolane with improved pharmacokinetic properties compared with other antimalarial drugs with the…”
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Effect of generalised access to early diagnosis and treatment and targeted mass drug administration on Plasmodium falciparum malaria in Eastern Myanmar: an observational study of a regional elimination programme by Landier, Jordi, Parker, Daniel M, Thu, Aung Myint, Lwin, Khin Maung, Delmas, Gilles, Nosten, François H, Andolina, Chiara, Aguas, Ricardo, Ang, Saw Moe, Aung, Ei Phyo, Baw, Naw Baw, Be, Saw Aye, B'Let, Saw, Bluh, Hay, Bonnington, Craig A., Chaumeau, Victor, Chirakiratinant, Miasa, Cho, Win Cho, Christensen, Peter, Corbel, Vincent, Day, Nicholas PJ, Dah, Saw Hsa, Delmas, Gilles, Dhorda, Mehul, Dondorp, Arjen M, Gaudart, Jean, Gornsawun, Gornpan, Haohankhunnatham, Warat, Hla, Saw Kyaw, Hsel, Saw Nay, Htoo, Gay Nay, Htoo, Saw Nay, Imwong, Mallika, John, Saw, Kajeechiwa, Ladda, Kereecharoen, Lily, Kittiphanakun, Praphan, Kittitawee, Keerati, Konghahong, Kamonchanok, Khin, Saw Diamond, Kyaw, Saw Win, Landier, Jordi, Ling, Clare, Lwin, Khin Maung, Lwin, Khine Shwe War, Ma, Naw K' Yin, Marie, Alexandra, Maung, Cynthia, Marta, Ed, Minh, Myo Chit, Miotto, Olivo, Moo, Paw Khu, Moo, Ku Ler, Moo, Merry, Na, Naw Na, Nay, Mar, Nosten, François H., Nosten, Suphak, Nyo, Slight Naw, Oh, Eh Kalu Shwe, Oo, Phu Thit, Oo, Tun Pyit, Parker, Daniel M., Paw, Eh Shee, Phumiya, Choochai, Phyo, Aung Pyae, Pilaseng, Kasiha, Proux, Stéphane, Rakthinthong, Santisuk, Ritwongsakul, Wannee, Salathibuphha, Kloloi, Santirad, Armon, Sawasdichai, Sunisa, von Seidlein, Lorenz, Shee, Paw Wah, Shee, Paw Bway, Tangseefa, Decha, Thu, Aung Myint, Thwin, May Myo, Tun, Saw Win, Wanachaloemlep, Chode, White, Lisa J, White, Nicholas J, Wiladphaingern, Jacher, Win, Saw Nyunt, Yee, Nan Lin, Yuwapan, Daraporn

“…Potentially untreatable Plasmodium falciparum malaria threatens the Greater Mekong subregion. A previous series of pilot projects in Myanmar, Laos, Cambodia,…”
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Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance by Cerqueira, Gustavo C, Cheeseman, Ian H, Schaffner, Steve F, Nair, Shalini, McDew-White, Marina, Phyo, Aung Pyae, Ashley, Elizabeth A, Melnikov, Alexandre, Rogov, Peter, Birren, Bruce W, Nosten, François, Anderson, Timothy J C, Neafsey, Daniel E

“…Artemisinin-based combination therapies are the first line of treatment for Plasmodium falciparum infections worldwide, but artemisinin resistance has risen…”
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Challenges to replace ACT as first-line drug by Phyo, Aung Pyae, von Seidlein, Lorenz

“…The spread of artemisinin and partner drug resistance through Asia requires changes in first-line therapy. The traditional modus has been the replacement of…”
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Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens by Chu, Cindy S, Bancone, Germana, Moore, Kerryn A, Win, Htun Htun, Thitipanawan, Niramon, Po, Christina, Chowwiwat, Nongnud, Raksapraidee, Rattanaporn, Wilairisak, Pornpimon, Phyo, Aung Pyae, Keereecharoen, Lily, Proux, Stéphane, Charunwatthana, Prakaykaew, Nosten, François, White, Nicholas J

“…Radical cure of Plasmodium vivax malaria with 8-aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with…”
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Malaria — Epidemiology, Treatment, and Prevention by Baden, Lindsey, Catteruccia, Flaminia, Diabaté, Abdoulaye, Donini, Cristina, Nosten, François, O’Neill, Scott, Osier, Faith, Phyo, Aung Pyae, White, Nicholas

“…This documentary video discusses the epidemiology of malaria; strategies for prevention, including vector control and vaccines; and the pipeline of promising…”
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