Search Results - "Pyśniak, Kazimiera"

Discovery of indazole-pyridinone derivatives as a novel class of potent and selective MNK1/2 kinase inhibitors that protecting against endotoxin-induced septic shock by Dreas, Agnieszka, Kucwaj-Brysz, Katarzyna, Pyziak, Karolina, Kulesza, Urszula, Wincza, Ewelina, Fabritius, Charles-Henry, Michalik, Kinga, Gabor-Worwa, Ewelina, Gołas, Aniela, Milik, Mariusz, Masiejczyk, Magdalena, Majewska, Eliza, Pyśniak, Kazimiera, Wójcik-Trechcińska, Urszula, Sandowska-Markiewicz, Zuzanna, Brzózka, Krzysztof, Ostrowski, Jerzy, Rzymski, Tomasz, Mikula, Michal

“…The mitogen-activated protein kinase (MAPK)-interacting kinases 1 and 2 (MNKs 1/2) and their downstream target eIF4E, play a role in oncogenic transformation,…”
Get full text

Limited Practical Utility of Liquid Biopsy in the Treated Patients with Advanced Breast Cancer by Niwinska, Anna, Bałabas, Aneta, Kulecka, Maria, Kluska, Anna, Piątkowska, Magdalena, Paziewska, Agnieszka, Pyśniak, Kazimiera, Olszewski, Wojciech, Mikula, Michał, Ostrowski, Jerzy

“…Recently, liquid biopsy has emerged as a tool to monitor oncologic disease progression and the effects of treatment. In this study we aimed to determine the…”
Get full text

Imatinib Inhibits the Renewal and Tumorigenicity of CT-26 Colon Cancer Cells after Cytoreductive Treatment with Doxorubicin by Przybyszewska, Małgorzata, Miłoszewska, Joanna, Kotlarz, Agnieszka, Swoboda, Paweł, Pyśniak, Kazimiera, Szczepek, Wojciech, Kaczmarek, Łukasz, Markowicz, Sergiusz

“…Conventional anti-cancer drugs preferentially eliminate differentiated cancer cells but those cells that are spared (i.e. cancer stem cells: CSC), initiate…”
Get full text

Foetal fibroblasts introduced to cleaving mouse embryos contribute to full-term development by Piliszek, Anna, Modliński, Jacek A, Pyśniak, Kazimiera, Karasiewicz, Jolanta

“…Foetal fibroblasts (FFs) labelled with vital fluorescent dye were microsurgically introduced into eight-cell mouse embryos, three cells to each embryo. FFs…”
Get full text

Soluble TNF-α Receptor I Encoded on Plasmid Vector and Its Application in Experimental Gene Therapy of Radiation-Induced Lung Fibrosis by Przybyszewska, Małgorzata, Miłoszewska, Joanna, Rzońca, Sylwia, Trembacz, Halina, Pyśniak, Kazimiera, Kotlarz, Agnieszka, Swoboda, Paweł, Zalewska, Marta, Małecki, Maciej

“…Post-radiation inflammatory reaction leads to an irreversible pulmonary fibrosis which may cause lethal respiratory insufficiency. Pathological inflammatory…”
Get full text

Effects of Soluble Dextrin Fiber from Potato Starch on Body Weight and Associated Gut Dysbiosis Are Evident in Western Diet-Fed Mice but Not in Overweight/Obese Children by Czarnowski, Paweł, Bałabas, Aneta, Kułaga, Zbigniew, Kulecka, Maria, Goryca, Krzysztof, Pyśniak, Kazimiera, Unrug-Bielawska, Katarzyna, Kluska, Anna, Bagińska-Drabiuk, Katarzyna, Głowienka-Stodolak, Maria, Piątkowska, Magdalena, Dąbrowska, Michalina, Żeber-Lubecka, Natalia, Wierzbicka-Rucińska, Aldona, Kotowska, Aneta, Więckowski, Sebastian, Mikula, Michał, Kapuśniak, Janusz, Socha, Piotr, Ostrowski, Jerzy

“…The study investigated the impact of starch degradation products (SDexF) as prebiotics on obesity management in mice and overweight/obese children. A total of…”
Get full text

Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models by Kopczynski, Michal, Rumienczyk, Izabela, Kulecka, Maria, Statkiewicz, Małgorzata, Pysniak, Kazimiera, Sandowska-Markiewicz, Zuzanna, Wojcik-Trechcinska, Urszula, Goryca, Krzysztof, Pyziak, Karolina, Majewska, Eliza, Masiejczyk, Magdalena, Wojcik-Jaszczynska, Katarzyna, Rzymski, Tomasz, Bomsztyk, Karol, Ostrowski, Jerzy, Mikula, Michal

“…Sepsis is the leading cause of death in intensive care units worldwide. Current treatments of sepsis are largely supportive and clinical trials using specific…”
Get full text

Prolonged transfer of feces from the lean mice modulates gut microbiota in obese mice by Kulecka, Maria, Paziewska, Agnieszka, Zeber-Lubecka, Natalia, Ambrozkiewicz, Filip, Kopczynski, Michal, Kuklinska, Urszula, Pysniak, Kazimiera, Gajewska, Marta, Mikula, Michal, Ostrowski, Jerzy

“…Transplanting a fecal sample from lean, healthy donors to obese recipients has been shown to improve metabolic syndrome symptoms. We therefore examined the gut…”
Get full text

Mutation Profiling of Premalignant Colorectal Neoplasia by Goryca, Krzysztof, Pachlewski, Jacek, Dabrowska, Michalina, Pysniak, Kazimiera, Paziewska, Agnieszka, Kulecka, Maria, Karczmarski, Jakub, Mroz, Andrzej, Michal, Mikula, Jerzy, Ostrowski, Lenarcik, Malgorzata

“…Accumulation of allelic variants in genes that regulate cellular proliferation, differentiation, and apoptosis may result in expansion of the aberrant…”
Get full text

Quantitative Trait Loci Analysis for Peripheral Blood Parameters in a (BALB/cW × C57BL/6J-Mpl hlb219/J) F2 Mice by STRZALKOWSKA, Adriana, UNRUG-BIELAWSKA, Katarzyna, BLUSZCZ, Aleksandra, SANDOWSKA-MARKIEWICZ, Zuzanna, KARASZEWSKA, Jadwiga, PYSNIAK, Kazimiera, GAJEWSKA, Marta, WIRTH-DZIECIOLOWSKA, Elzbieta

“…The genetic basis of the peripheral blood cell parameters is not fully elucidated. Thus, it is essential to research the correlation between blood cell counts…”
Get full text

Mitochondrial amidoxime-reducing component 2 (MARC2) has a significant role in N-reductive activity and energy metabolism by Rixen, Sophia, Havemeyer, Antje, Tyl-Bielicka, Anita, Pysniak, Kazimiera, Gajewska, Marta, Kulecka, Maria, Ostrowski, Jerzy, Mikula, Michal, Clement, Bernd

“…The mitochondrial amidoxime-reducing component (MARC) is a mammalian molybdenum-containing enzyme. All annotated mammalian genomes harbor two MARC genes, MARC1…”
Get full text

Extracellular matrix and cytochrome P450 gene expression can distinguish steatohepatitis from steatosis in mice by Hennig, Ewa E., Mikula, Michal, Goryca, Krzysztof, Paziewska, Agnieszka, Ledwon, Joanna, Nesteruk, Monika, Woszczynski, Marek, Walewska‐Zielecka, Bozena, Pysniak, Kazimiera, Ostrowski, Jerzy

“…One of the main questions regarding nonalcoholic fatty liver disease is the molecular background of the transition from simple steatosis (SS) to the…”
Get full text

Chronic mild stress facilitates melanoma tumor growth in mouse lines selected for high and low stress-induced analgesia by Ragan, Agnieszka R, Lesniak, Anna, Bochynska-Czyz, Marta, Kosson, Anna, Szymanska, Hanna, Pysniak, Kazimiera, Gajewska, Marta, Lipkowski, Andrzej W, Sacharczuk, Mariusz

“…Both chronic stress conditions and hyperergic reaction to environmental stress are known to enhance cancer susceptibility. We described two mouse lines that…”
Get more information

Soluble TNF- Delta a Receptor I Encoded on Plasmid Vector and Its Application in Experimental Gene Therapy of Radiation-Induced Lung Fibrosis by Przybyszewska, Malgorzata, Miloszewska, Joanna, Rzonca, Sylwia, Trembacz, Halina, Pysniak, Kazimiera, Kotlarz, Agnieszka, Swoboda, Pawel, Zalewska, Marta, Malecki, Maciej

“…Post-radiation inflammatory reaction leads to an irreversible pulmonary fibrosis which may cause lethal respiratory insufficiency. Pathological inflammatory…”
Get full text

Opposite effects of modifiers of the ApcMin mutation in intestine and mammary gland by CZARNOMSKA, Alina, KRYSIAK, Elzbieta, PISKOROWSKA, Joanna, SITARZ, Miroslawa, PYSNIAK, Kazimiera, PILCIK, Tomas, DEMANT, Peter

“…Patterns of tumor susceptibility in different organs are widely divergent in mouse strains: one strain may be highly susceptible to tumors in one organ but…”
Get full text

Quantitative trait loci analysis for peripheral blood parameters in a (BALB/cW × C57BL/6J-Mpl (hlb219)/J) F(2) mice by Strzalkowska, Adriana, Unrug-Bielawska, Katarzyna, Bluszcz, Aleksandra, Sandowska-Markiewicz, Zuzanna, Karaszewska, Jadwiga, Pysniak, Kazimiera, Gajewska, Marta, Wirth-Dzieciolowska, Elzbieta

“…The genetic basis of the peripheral blood cell parameters is not fully elucidated. Thus, it is essential to research the correlation between blood cell counts…”
Get more information