Search Results - "Puvenna, Vikram"
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The role of shear stress in Blood-Brain Barrier endothelial physiology
Published in BMC neuroscience (11-05-2011)“…One of the most important and often neglected physiological stimuli contributing to the differentiation of vascular endothelial cells (ECs) into a blood-brain…”
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Consequences of repeated blood-brain barrier disruption in football players
Published in PloS one (06-03-2013)“…The acknowledgement of risks for traumatic brain injury in American football players has prompted studies for sideline concussion diagnosis and testing for…”
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Is phosphorylated tau unique to chronic traumatic encephalopathy? Phosphorylated tau in epileptic brain and chronic traumatic encephalopathy
Published in Brain research (01-01-2016)“…Abstract Repetitive traumatic brain injury (rTBI) is one of the major risk factors for the abnormal deposition of phosphorylated tau (PT) in the brain and…”
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Efficacy of anti-inflammatory therapy in a model of acute seizures and in a population of pediatric drug resistant epileptics
Published in PloS one (28-03-2011)“…Targeting pro-inflammatory events to reduce seizures is gaining momentum. Experimentally, antagonism of inflammatory processes and of blood-brain barrier (BBB)…”
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Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits
Published in PloS one (07-05-2014)“…The impact of sub-concussive head hits (sub-CHIs) has been recently investigated in American football players, a population at risk for varying degrees of…”
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Blood-brain barrier P450 enzymes and multidrug transporters in drug resistance: a synergistic role in neurological diseases
Published in Current drug metabolism (01-10-2011)“…Drug penetration into the central nervous system (CNS) is controlled by the blood-brain barrier (BBB). Even though a number of strategies to circumvent the BBB…”
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Is peripheral immunity regulated by blood-brain barrier permeability changes?
Published in PloS one (02-07-2014)“…S100B is a reporter of blood-brain barrier (BBB) integrity which appears in blood when the BBB is breached. Circulating S100B derives from either extracranial…”
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Modulation of peripheral cytotoxic cells and ictogenesis in a model of seizures
Published in Epilepsia (Copenhagen) (01-09-2011)“…Summary Purpose: A link between seizure susceptibility, blood–brain barrier (BBB) failure, and the activation of peripheral white blood cells has been…”
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Comparable levels of phosphorylated tau in epileptic brain and chronic traumatic encephalopathy (P7.154)
Published in Neurology (06-04-2015)“…Abstract only…”
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Expression and functional relevance of UGT1A4 in a cohort of human drug‐resistant epileptic brains
Published in Epilepsia (Copenhagen) (01-09-2013)“…Summary Purpose Brain drug bioavailability is regulated by the blood–brain barrier (BBB). It was recently suggested that cytochrome P450 (CYP) enzymes could…”
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Pathophysiological impact of cigarette smoke exposure on the cerebrovascular system with a focus on the blood-brain barrier: expanding the awareness of smoking toxicity in an underappreciated area
Published in International journal of environmental research and public health (01-12-2010)“…Recent evidence has indicated that active and passive cigarette smoking are associated, in a dose-dependent manner, with dysfunction of normal endothelial…”
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Cellular localization and functional significance of CYP3A4 in the human epileptic brain
Published in Epilepsia (Copenhagen) (01-03-2011)“…Summary Purpose: Compelling evidence supports the presence of P450 enzymes (CYPs) in the central nervous system (CNS). However, little information is…”
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Anti-S100B autoantibodies in cerebral small vessel disease (S33.005)
Published in Neurology (06-04-2015)“…Abstract only…”
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Anti-S100B autoantibodies in cerebral small vessel disease (I9-1A)
Published in Neurology (06-04-2015)“…Abstract only…”
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S100B and S100B autoantibody as biomarkers for early detection of brain metastases in lung cancer
Published in Translational lung cancer research (01-08-2016)Get full text
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Levels of S100B in brain and blood of rats with diabetic ketoacidosis
Published in Brain research (22-10-2015)“…Abstract Diabetic ketoacidosis (DKA) frequently causes subtle brain injuries in children. Rarely, these injuries can be severe and life threatening. The…”
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Expression and functional relevance of UGT 1 A 4 in a cohort of human drug‐resistant epileptic brains
Published in Epilepsia (Copenhagen) (01-09-2013)Get full text
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The Etiological Role of Blood-Brain Barrier Dysfunction in Seizure Disorders
Published in Cardiovascular Psychiatry and Neurology (2011)“…A wind of change characterizes epilepsy research efforts. The traditional approach, based on a neurocentric view of seizure generation, promoted understanding…”
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Cellular localization and functional significance of CYP3A4 in the human epileptic brain: CYP3A4 in the Drug-Resistant Brain
Published in Epilepsia (Copenhagen) (01-03-2011)Get full text
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Modulation of peripheral cytotoxic cells and ictogenesis in a model of seizures: Intravascular Inflammation and Seizures
Published in Epilepsia (Copenhagen) (01-09-2011)Get full text
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