Search Results - "Puvenna, Vikram"

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    The role of shear stress in Blood-Brain Barrier endothelial physiology by Cucullo, Luca, Hossain, Mohammed, Puvenna, Vikram, Marchi, Nicola, Janigro, Damir

    Published in BMC neuroscience (11-05-2011)
    “…One of the most important and often neglected physiological stimuli contributing to the differentiation of vascular endothelial cells (ECs) into a blood-brain…”
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    Consequences of repeated blood-brain barrier disruption in football players by Marchi, Nicola, Bazarian, Jeffrey J, Puvenna, Vikram, Janigro, Mattia, Ghosh, Chaitali, Zhong, Jianhui, Zhu, Tong, Blackman, Eric, Stewart, Desiree, Ellis, Jasmina, Butler, Robert, Janigro, Damir

    Published in PloS one (06-03-2013)
    “…The acknowledgement of risks for traumatic brain injury in American football players has prompted studies for sideline concussion diagnosis and testing for…”
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    Efficacy of anti-inflammatory therapy in a model of acute seizures and in a population of pediatric drug resistant epileptics by Marchi, Nicola, Granata, Tiziana, Freri, Elena, Ciusani, Emilio, Ragona, Francesca, Puvenna, Vikram, Teng, Quingshan, Alexopolous, Andreas, Janigro, Damir

    Published in PloS one (28-03-2011)
    “…Targeting pro-inflammatory events to reduce seizures is gaining momentum. Experimentally, antagonism of inflammatory processes and of blood-brain barrier (BBB)…”
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    Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits by Puvenna, Vikram, Brennan, Chanda, Shaw, Gerald, Yang, Cui, Marchi, Nicola, Bazarian, Jeffrey J, Merchant-Borna, Kian, Janigro, Damir

    Published in PloS one (07-05-2014)
    “…The impact of sub-concussive head hits (sub-CHIs) has been recently investigated in American football players, a population at risk for varying degrees of…”
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    Blood-brain barrier P450 enzymes and multidrug transporters in drug resistance: a synergistic role in neurological diseases by Ghosh, Chaitali, Puvenna, Vikram, Gonzalez-Martinez, Jorge, Janigro, Damir, Marchi, Nicola

    Published in Current drug metabolism (01-10-2011)
    “…Drug penetration into the central nervous system (CNS) is controlled by the blood-brain barrier (BBB). Even though a number of strategies to circumvent the BBB…”
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    Is peripheral immunity regulated by blood-brain barrier permeability changes? by Bargerstock, Erin, Puvenna, Vikram, Iffland, Philip, Falcone, Tatiana, Hossain, Mohammad, Vetter, Stephen, Man, Shumei, Dickstein, Leah, Marchi, Nicola, Ghosh, Chaitali, Carvalho-Tavares, Juliana, Janigro, Damir

    Published in PloS one (02-07-2014)
    “…S100B is a reporter of blood-brain barrier (BBB) integrity which appears in blood when the BBB is breached. Circulating S100B derives from either extracranial…”
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    Modulation of peripheral cytotoxic cells and ictogenesis in a model of seizures by Marchi, Nicola, Johnson, Aaron J., Puvenna, Vikram, Johnson, Holly L., Tierney, William, Ghosh, Chaitali, Cucullo, Luca, Fabene, Paolo F., Janigro, Damir

    Published in Epilepsia (Copenhagen) (01-09-2011)
    “…Summary Purpose:  A link between seizure susceptibility, blood–brain barrier (BBB) failure, and the activation of peripheral white blood cells has been…”
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    Expression and functional relevance of UGT1A4 in a cohort of human drug‐resistant epileptic brains by Ghosh, Chaitali, Hossain, Mohammed, Puvenna, Vikram, Martinez‐Gonzalez, Jorge, Alexopolous, Andreas, Janigro, Damir, Marchi, Nicola

    Published in Epilepsia (Copenhagen) (01-09-2013)
    “…Summary Purpose Brain drug bioavailability is regulated by the blood–brain barrier (BBB). It was recently suggested that cytochrome P450 (CYP) enzymes could…”
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    Cellular localization and functional significance of CYP3A4 in the human epileptic brain by Ghosh, Chaitali, Marchi, Nicola, Desai, Nirav K., Puvenna, Vikram, Hossain, Mohammed, Gonzalez‐Martinez, Jorge, Alexopoulos, Andreas V., Janigro, Damir

    Published in Epilepsia (Copenhagen) (01-03-2011)
    “…Summary Purpose:  Compelling evidence supports the presence of P450 enzymes (CYPs) in the central nervous system (CNS). However, little information is…”
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    Levels of S100B in brain and blood of rats with diabetic ketoacidosis by Glaser, Nicole, Lo, Weei, Tancredi, Daniel, Orgain, Myra, Puvenna, Vikram, Janigro, Damir, O׳Donnell, Martha

    Published in Brain research (22-10-2015)
    “…Abstract Diabetic ketoacidosis (DKA) frequently causes subtle brain injuries in children. Rarely, these injuries can be severe and life threatening. The…”
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    The Etiological Role of Blood-Brain Barrier Dysfunction in Seizure Disorders by Janigro, Damir, Granata, Tiziana, Puvenna, Vikram, Alexopoulos, Andreas V., Tierney, William, Marchi, Nicola

    “…A wind of change characterizes epilepsy research efforts. The traditional approach, based on a neurocentric view of seizure generation, promoted understanding…”
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