Search Results - "Putnam, D."

Strand discrimination in DNA mismatch repair by Putnam, Christopher D.

“…•DNA mismatch repair must distinguish the daughter and parental strands.•Strand discrimination at a distance depends on MutL homologs and replicative…”
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Religion, Social Networks, and Life Satisfaction by Lim, Chaeyoon, Putnam, Robert D.

“…Although the positive association between religiosity and life satisfaction is well documented, much theoretical and empirical controversy surrounds the…”
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E Pluribus Unum: Diversity and Community in the Twenty-first Century The 2006 Johan Skytte Prize Lecture by Putnam, Robert D.

“…Ethnic diversity is increasing in most advanced countries, driven mostly by sharp increases in immigration. In the long run immigration and diversity are…”
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Evolution of the methyl directed mismatch repair system in Escherichia coli by Putnam, Christopher D.

“…•E. coli contains an unusual methyl-directed mismatch repair (mdMMR) pathway.•The mdMMR arose in an ancestor to a subset of Gammaproteobacteria (the EPVAA…”
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Increasing socioeconomic disparities in adolescent obesity by Frederick, Carl B., Snellman, Kaisa, Putnam, Robert D.

“…Recent reports suggest that the rapid growth in youth obesity seen in the 1980s and 1990s has plateaued. We examine changes in obesity among US adolescents…”
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The social context of well–being by Huppert, F. A., Baylis, N., Keverne, B., Helliwell, John F., Putnam, Robert D.

“…Large samples of data from the World Values Survey, the US Benchmark Survey and a comparable Canadian survey are used to estimate equations designed to explore…”
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PCNA and Msh2-Msh6 Activate an Mlh1-Pms1 Endonuclease Pathway Required for Exo1-Independent Mismatch Repair by Goellner, Eva M., Smith, Catherine E., Campbell, Christopher S., Hombauer, Hans, Desai, Arshad, Putnam, Christopher D., Kolodner, Richard D.

“…Genetic evidence has implicated multiple pathways in eukaryotic DNA mismatch repair (MMR) downstream of mispair recognition and Mlh1-Pms1 recruitment,…”
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Alternative splicing regulates stochastic NLRP3 activity by Hoss, Florian, Mueller, James L., Rojas Ringeling, Francisca, Rodriguez-Alcazar, Juan F., Brinkschulte, Rebecca, Seifert, Gerald, Stahl, Rainer, Broderick, Lori, Putnam, Chris D., Kolodner, Richard D., Canzar, Stefan, Geyer, Matthias, Hoffman, Hal M., Latz, Eicke

“…Leucine-rich repeat (LRR) domains are evolutionarily conserved in proteins that function in development and immunity. Here we report strict exonic modularity…”
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Specific pathways prevent duplication-mediated genome rearrangements by Kolodner, Richard D, Putnam, Christopher D, Hayes, Tikvah K

“…We have investigated the ability of different regions of the left arm of Saccharomyces cerevisiae chromosome V to participate in the formation of gross…”
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Rad27 and Exo1 function in different excision pathways for mismatch repair in Saccharomyces cerevisiae by Calil, Felipe A., Li, Bin-Zhong, Torres, Kendall A., Nguyen, Katarina, Bowen, Nikki, Putnam, Christopher D., Kolodner, Richard D.

“…Eukaryotic DNA Mismatch Repair (MMR) involves redundant exonuclease 1 (Exo1)-dependent and Exo1-independent pathways, of which the Exo1-independent pathway(s)…”
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Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae by Li, Bin-Zhong, Putnam, Christopher D, Kolodner, Richard David

“…Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a genetic system that generates…”
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Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae by Campbell, Christopher S, Hombauer, Hans, Srivatsan, Anjana, Bowen, Nikki, Gries, Kerstin, Desai, Arshad, Putnam, Christopher D, Kolodner, Richard D

“…In Saccharomyces cerevisiae, the essential mismatch repair (MMR) endonuclease Mlh1-Pms1 forms foci promoted by Msh2-Msh6 or Msh2-Msh3 in response to mispaired…”
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Mutations in topoisomerase IIβ result in a B cell immunodeficiency by Broderick, Lori, Yost, Shawn, Li, Dong, McGeough, Matthew D., Booshehri, Laela M., Guaderrama, Marisela, Brydges, Susannah D., Kucharova, Karolina, Patel, Niraj C., Harr, Margaret, Hakonarson, Hakon, Zackai, Elaine, Cowell, Ian G., Austin, Caroline A., Hügle, Boris, Gebauer, Corinna, Zhang, Jianguo, Xu, Xun, Wang, Jian, Croker, Ben A., Frazer, Kelly A., Putnam, Christopher D., Hoffman, Hal M.

“…B cell development is a highly regulated process involving multiple differentiation steps, yet many details regarding this pathway remain unknown. Sequencing…”
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The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects by Srivatsan, Anjana, Li, Bin-Zhong, Szakal, Barnabas, Branzei, Dana, Putnam, Christopher D., Kolodner, Richard D.

“…Genome instability is associated with tumorigenesis. Here, we identify a role for the histone Htz1, which is deposited by the Swr1 chromatin-remodeling complex…”
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Distinct SUMO ligases cooperate with Esc2 and Slx5 to suppress duplication-mediated genome rearrangements by Albuquerque, Claudio P, Wang, Guoliang, Lee, Nancy S, Kolodner, Richard D, Putnam, Christopher D, Zhou, Huilin

“…Suppression of duplication-mediated gross chromosomal rearrangements (GCRs) is essential to maintain genome integrity in eukaryotes. Here we report that SUMO…”
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The effects of periparturient administration of flunixin meglumine on the health and production of dairy cattle by Newby, N C, Leslie, K E, Dingwell, H D Putnam, Kelton, D F, Weary, D M, Neuder, L, Millman, S T, Duffield, T F

“…Research on the assessment and management of pain in cows following difficult or assisted calving is still limited, especially on the effects of analgesics…”
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Maintenance of Genome Stability in Saccharomyces cerevisiae by Kolodner, Richard D., Putnam, Christopher D., Myung, Kyungjae

“…Most human cancer cells show signs of genome instability, ranging from elevated mutation rates to gross chromosomal rearrangements and alterations in…”
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SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements by Liang, Jason, Li, Bin-Zhong, Tan, Alexander P, Kolodner, Richard D, Putnam, Christopher D, Zhou, Huilin

“…Mms21, a subunit of the Smc5/6 complex, possesses an E3 ligase activity for the Small Ubiquitin-like MOdifier (SUMO). Here we show that the mms21-CH mutation,…”
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Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway by Smith, Catherine E, Mendillo, Marc L, Bowen, Nikki, Hombauer, Hans, Campbell, Christopher S, Desai, Arshad, Putnam, Christopher D, Kolodner, Richard D

“…Lynch syndrome (hereditary nonpolypsis colorectal cancer or HNPCC) is a common cancer predisposition syndrome. Predisposition to cancer in this syndrome…”
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Treatment of Distal Radius Fractures by Lichtman, David M, Bindra, Randipsingh R, Boyer, Martin I, Putnam, Matthew D, Ring, David, Slutsky, David J, Taras, John S, Watters, 3rd, William C, Goldberg, Michael J, Keith, Michael, Turkelson, Charles M, Wies, Janet L, Haralson, 3rd, Robert H, Boyer, Kevin M, Hitchcock, Kristin, Raymond, Laura

“…The clinical practice guideline is based on a systematic review of published studies on the treatment of distal radius fractures in adults. None of the 29…”
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