Search Results - "Pustylnyak, V. O"
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The constitutive androstane receptor activator 4‐[(4R,6R)‐4,6‐diphenyl‐1,3‐dioxan‐2‐yl]‐N,N‐dimethylaniline inhibits the gluconeogenic genes PEPCK and G6Pase through the suppression of HNF4α and FOXO1 transcriptional activity
Published in British journal of pharmacology (01-04-2013)“…Background and Purpose The dual role of the constitutive androstane receptor (CAR) as both a xenosensor and a regulator of endogenous energy metabolism…”
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Constitutive androstane receptor (CAR) is a xenosensor and target for therapy
Published in Biochemistry (Moscow) (01-10-2011)“…Constitutive androstane receptor (CAR, NR1I3), which is under consideration in this review, is a member of the superfamily of nuclear receptors. However,…”
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Sirt1 Regulates p53 Stability and Expression of Its Target S100B during Long-Term Potentiation in Rat Hippocampus
Published in Bulletin of experimental biology and medicine (01-02-2016)“…Induction of long-term potentiation in rat hippocampus was followed by short-term activation of transcription factor p53 and its subsequent degradation. We…”
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Induction of cytochrome P4502B: role of regulatory elements and nuclear receptors
Published in Biochemistry (Moscow) (01-06-2007)“…Cytochrome P450 of the 2B subfamily is easily induced by many xenobiotics. In spite of intensive investigations, the molecular mechanisms of regulation of the…”
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Mdm2-Dependent Regulation of p53 Expression during Long-Term Potentiation
Published in Bulletin of experimental biology and medicine (01-01-2015)“…Induction of long-term posttetanic potentiation in rat hippocampal CA1 filed was followed by a decrease in the content of transcription factor p53 against the…”
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Role of nuclear constitutive androstane receptor in regulation of hepatocyte proliferation and hepatocarcinogenesis
Published in Biochemistry (Moscow) (01-04-2016)“…Activation of the constitutive androstane receptor (CAR) in hepatocytes occurs as a body adaptation in response to a number of external influences, and its…”
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Induction of S100B Gene Expression in Long-Term Potentiation in the Hippocampal CA1 Field Depends on Activity of NMDA Receptors
Published in Bulletin of experimental biology and medicine (01-02-2013)“…The effects of NMDA receptor blocker MK-801 on the increase in S100B protein mRNA content induced by long-term posttetanic potentiation in the hippocampal…”
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Expression of S100B and S100A6 Genes during Long-Term Posttetanic Potentiation in the Hippocampus
Published in Bulletin of experimental biology and medicine (01-08-2009)“…The expression of S100B and S100A6 mRNA in CA1 region of rat hippocampal sections was studied after tetanizing stimulation. The level of S100B expression…”
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Gene expression of androgen metabolising enzymes in benign and malignant prostatic tissues
Published in Hormone and metabolic research (01-02-2015)“…Benign prostatic hyperplasia (BPH) as well as prostate cancer (CaP) are prevalent in the aging male population, and both the diseases display…”
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Expression of Bcl2 Family Genes in the Early Phase of Long-Term Potentiation
Published in Bulletin of experimental biology and medicine (01-11-2014)“…Expression of Bcl2 family genes was studied during the early phase of long-term potentiation in the CA1 field of rat hippocampal slices. The level of Bax mRNA…”
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Dynamics of DNA-protein complex formation in rat liver during induction by phenobarbital and triphenyldioxane
Published in Biochemistry (Moscow) (01-10-2004)“…CYP2B gene expression in liver of rats treated with phenobarbital and triphenyldioxane at early stage of induction (40 min-18 h) was studied using…”
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Tissue-specific expression of hormonal carcinogenesis target genes in rats treated with polycyclic aromatic hydrocarbons
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-09-2011)“…We have investigated the effect of polycyclic aromatic hydrocarbons (PAHs) on expression of the estrogen-metabolizing genes CYP1A1 , CYP1B1 , CYP19 and also ER…”
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A pseudovirus system for the testing of antiviral activity of compounds in different cell lines
Published in Doklady. Biochemistry and biophysics (01-12-2010)“…The use of pseudovirus target cell systems using infection permissive indicator cells and T lymphoid and monocyte lineages that are close to natural targets…”
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Time Course of Expression of “Early” Genes during Long-Term Posttetanic Potentiation in Rat Hippocampal CA1 Field
Published in Bulletin of experimental biology and medicine (01-09-2009)“…The expression of egr-1, junB, c-jun, and c-fos genes in rat hippocampal CA1 fi eld was studied by the real-time PCR 30, 60, and 120 min after induction of…”
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Regulation of S100B Expression in Long-Term Potentiation
Published in Neuroscience and behavioral physiology (01-03-2016)“…The role of intracellular regulatory cascades in inducing the expression of S100B during the formation of long-term post-tetanic potentiation (LTP) in field…”
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Effect of triphenyldioxane on phase I xenobiotic metabolism enzymes in the liver of rats and rabbits
Published in Bulletin of experimental biology and medicine (01-06-2006)“…We studied the effect of triphenyldioxane on phase I xenobiotic metabolism enzymes in the liver of rats and rabbits. Total cytochrome P450 content, protein…”
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The constitutive androstane receptor activator 4-[(4R,6R)-4,6-diphenyl-1,3-dioxan-2-yl]-N,N-dimethylaniline inhibits the gluconeogenic genes PEPCK and G6Pase through the suppression of HNF4[alpha] and FOXO1 transcriptional activity
Published in British journal of pharmacology (01-04-2013)“…Background and Purpose The dual role of the constitutive androstane receptor (CAR) as both a xenosensor and a regulator of endogenous energy metabolism…”
Get full text
Journal Article -
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MODERN APPROACH TO MOLECULAR CHARACTERIZATION OF PROSTATE TUMORS
Published in Acta biomedica scientifica (01-05-2012)“…The aim of the study was the development of a cell biosensor system based on the fact that AR activator stimuli lead to redistribution of AR from cytoplasm to…”
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Tissue-specific expression of hormonal carcinogenesis target genes in rats treated with polycyclic aromatic hydrocarbons
Published in Biomeditsinskaia khimiia (01-05-2012)“…We have investigated the effect of polycyclic aromatic hydrocarbons (PAHs) on estrogen-metabolizing genes CYP1A1, CYP1B1, CYP19 and ERalpha and cyclin D1…”
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Genetic polymorphism of estrogen metabolizing enzymes in Siberian women with breast cancer
Published in Genetic testing and molecular biomarkers (01-03-2012)“…Allelic variants of cytochrome P450: CYP1A1, CYP1A2, CYP19 (aromatase), and the II-phase enzyme sulfotransferase 1A1 (SULT1A1) genes are associated with a high…”
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