Search Results - "Pustovalova, Olga"
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Drug target prediction and repositioning using an integrated network-based approach
Published in PloS one (04-04-2013)“…The discovery of novel drug targets is a significant challenge in drug development. Although the human genome comprises approximately 30,000 genes, proteins…”
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Journal Article -
2
Development of a Drug-Response Modeling Framework to Identify Cell Line Derived Translational Biomarkers That Can Predict Treatment Outcome to Erlotinib or Sorafenib
Published in PloS one (24-06-2015)“…Development of drug responsive biomarkers from pre-clinical data is a critical step in drug discovery, as it enables patient stratification in clinical trial…”
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Journal Article -
3
An integrated map of HIV-human protein complexes that facilitate viral infection
Published in PloS one (09-05-2014)“…Recent proteomic and genetic studies have aimed to identify a complete network of interactions between HIV and human proteins and genes. This HIV-human…”
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Journal Article -
4
Widespread distribution of HLA-DR-expressing cells in macroscopically undiseased intima of the human aorta: A possible role in surveillance and maintenance of vascular homeostasis
Published in Immunobiology (1979) (01-05-2012)“…Abstract The architectonics and cell composition of the human large arteries are not sufficiently understood. The present study is the first to undertake an…”
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Journal Article -
5
Functional Synergies yet Distinct Modulators Affected by Genetic Alterations in Common Human Cancers
Published in Cancer research (Chicago, Ill.) (15-05-2011)“…An important general concern in cancer research is how diverse genetic alterations and regulatory pathways can produce common signaling outcomes. In this…”
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6
Profiling Secreted miRNA Biomarkers of Chemical-Induced Neurodegeneration in Human iPSC-Derived Neurons
Published in Toxicological sciences (28-03-2022)“…Abstract Elucidation of predictive fluidic biochemical markers to detect and monitor chemical-induced neurodegeneration has been a major challenge due to a…”
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Journal Article -
7
Tissue regeneration in vivo within recombinant spidroin 1 scaffolds
Published in Biomaterials (01-05-2012)“…Abstract One of the major tasks of tissue engineering is to produce tissue grafts for the replacement or regeneration of damaged tissue, and natural and…”
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Journal Article -
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Abstract A37: Translational biomarkers for cancer drug response: Cell line panel derived drug response signature predicts patients’ survival in a lung cancer clinic trial
Published in Molecular cancer therapeutics (01-11-2013)“…Abstract Discovery of candidate drug sensitivity predictive genomic models using pre-clinical data would significantly advance the ability to timely validate…”
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Journal Article -
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An Integrated Map of HIV-Human Protein Complexes that Facilitate Viral Infection: e96687
Published in PloS one (01-05-2014)“…Recent proteomic and genetic studies have aimed to identify a complete network of interactions between HIV and human proteins and genes. This HIV-human…”
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Journal Article -
10
Mathematical Modelling of Circular Corrugated Membranes
Published in 2018 5th International Conference on Mathematics and Computers in Sciences and Industry (MCSI) (01-08-2018)“…The paper presents a technique for determining bifurcation points for circular corrugated membranes. The applied Kirchhoff-Love theory for non-shallow shells…”
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Conference Proceeding -
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Semi-analytical Study of Large Bending Strains of the Inhomogeneous Bar
Published in 2018 5th International Conference on Mathematics and Computers in Sciences and Industry (MCSI) (01-08-2018)“…This paper presents an analysis of the problem of pure bending of an inhomogeneous nonlinearly elastic bar with rectangular cross-section. The character of…”
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Conference Proceeding