Search Results - "Puspitasari, Yustina M"

Sirtuin 1 in Endothelial Dysfunction and Cardiovascular Aging by Ministrini, Stefano, Puspitasari, Yustina M., Beer, Georgia, Liberale, Luca, Montecucco, Fabrizio, Camici, Giovanni G.

“…Sirtuin 1 (SIRT1) is a histone deacetylase belonging to the family of Sirtuins, a class of nicotinamide adenine dinucleotide (NAD+)-dependent enzymes with…”
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Serum circulating sirtuin 6 as a novel predictor of mortality after acute ischemic stroke by Liberale, Luca, Ministrini, Stefano, Arnold, Markus, Puspitasari, Yustina M., Pokorny, Thomas, Beer, Georgia, Scherrer, Natalie, Schweizer, Juliane, Christ-Crain, Mirjam, Montecucco, Fabrizio, Camici, Giovanni G., Katan Kahles, Mira

“…In a murine model of acute ischemic stroke, SIRT6 knockdown resulted in larger cerebral infarct size, worse neurological outcome, and higher mortality,…”
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Modern Concepts in Cardiovascular Disease: Inflamm-Aging by Puspitasari, Yustina M, Ministrini, Stefano, Schwarz, Lena, Karch, Caroline, Liberale, Luca, Camici, Giovanni G

“…The improvements in healthcare services and quality of life result in a longer life expectancy and a higher number of aged individuals, who are inevitably…”
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Sirtuin 2 in vascular ageing: the forsaken child? by Puspitasari, Yustina M

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JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study by Liberale, Luca, Puspitasari, Yustina M, Ministrini, Stefano, Akhmedov, Alexander, Kraler, Simon, Bonetti, Nicole R, Beer, Georgia, Vukolic, Ana, Bongiovanni, Dario, Han, Jiaying, Kirmes, Kilian, Bernlochner, Isabell, Pelisek, Jaroslav, Beer, Jürg H, Jin, Zheng-Gen, Pedicino, Daniela, Liuzzo, Giovanna, Stellos, Konstantinos, Montecucco, Fabrizio, Crea, Filippo, Lüscher, Thomas F, Camici, Giovanni G

“…Abstract Aims Variants of the junctional cadherin 5 associated (JCAD) locus associate with acute coronary syndromes. JCAD promotes experimental atherosclerosis…”
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MMP-2 knockdown blunts age-dependent carotid stiffness by decreasing elastin degradation and augmenting eNOS activation by Diaz-Canestro, Candela, Puspitasari, Yustina M, Liberale, Luca, Guzik, Tomasz J, Flammer, Andreas J, Bonetti, Nicole R, Wüst, Patricia, Costantino, Sarah, Paneni, Francesco, Akhmedov, Alexander, Varga, Zsuzsanna, Ministrini, Stefano, Beer, Jürg H, Ruschitzka, Frank, Hermann, Matthias, Lüscher, Thomas F, Sudano, Isabella, Camici, Giovanni G

“…Abstract Aims Arterial stiffness is a hallmark of vascular ageing that precedes and strongly predicts the development of cardiovascular diseases. Age-dependent…”
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Postischemic Administration of IL-1α Neutralizing Antibody Reduces Brain Damage and Neurological Deficit in Experimental Stroke by Liberale, Luca, Bonetti, Nicole R., Puspitasari, Yustina M., Schwarz, Lena, Akhmedov, Alexander, Montecucco, Fabrizio, Ruschitzka, Frank, Beer, Jürg H., Lüscher, Thomas F., Simard, John, Libby, Peter, Camici, Giovanni G.

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SGLT-2 inhibition by empagliflozin has no effect on experimental arterial thrombosis in a murine model of low-grade inflammation by Liberale, Luca, Kraler, Simon, Puspitasari, Yustina M, Bonetti, Nicole R, Akhmedov, Alexander, Ministrini, Stefano, Montecucco, Fabrizio, Marx, Nikolaus, Lehrke, Michael, Hartmann, Niels-Ulrik K, Beer, Jürg H, Wenzl, Florian A, Paneni, Francesco, Lüscher, Thomas F, Camici, Giovanni G

“…Abstract Aims Low-grade inflammation couples dysmetabolic states to insulin resistance and atherosclerotic cardiovascular (CV) disease (ASCVD). Selective…”
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Antibody-mediated PCSK9 neutralization worsens outcome after bare-metal stent implantation in mice by Puspitasari, Yustina M., Ministrini, Stefano, Liberale, Luca, Vukolic, Ana, Baumann-Zumstein, Philine, Holy, Erik W., Montecucco, Fabrizio, Lüscher, Thomas F., Camici, Giovanni G.

“…Despite advances in pharmacotherapy and device innovation, in-stent restenosis (ISR) and stent thrombosis (ST) remain serious complications following…”
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TNF‐α antagonism rescues the effect of ageing on stroke: Perspectives for targeting inflamm‐ageing by Liberale, Luca, Bonetti, Nicole R., Puspitasari, Yustina M., Vukolic, Ana, Akhmedov, Alexander, Diaz‐Cañestro, Candela, Keller, Stephan, Montecucco, Fabrizio, Merlini, Mario, Semerano, Aurora, Giacalone, Giacomo, Bacigaluppi, Marco, Sessa, Maria, Ruschitzka, Frank, Lüscher, Thomas F., Libby, Peter, Beer, Jürg H., Camici, Giovanni G.

“…Aims Epidemiologic evidence links ischemic stroke to age, yet the mechanisms that underlie the specific and independent effects of age on stroke remain…”
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Sirtuin 5 promotes arterial thrombosis by blunting the fibrinolytic system by Liberale, Luca, Akhmedov, Alexander, Vlachogiannis, Nikolaos I, Bonetti, Nicole R, Nageswaran, Vanasa, Miranda, Melroy X, Puspitasari, Yustina M, Schwarz, Lena, Costantino, Sarah, Paneni, Francesco, Beer, Jürg H, Ruschitzka, Frank, Montecucco, Fabrizio, Lüscher, Thomas F, Stamatelopoulos, Kimon, Stellos, Konstantinos, Camici, Giovanni G

“…Abstract Aims Arterial thrombosis as a result of plaque rupture or erosion is a key event in acute cardiovascular events. Sirtuin 5 (SIRT5) belongs to the…”
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Hutchinson-Gilford progeria syndrome mice display accelerated arterial thrombus formation and increased platelet reactivity by Puspitasari, Yustina M., Ministrini, Stefano, Han, Jiaying, Karch, Caroline, Prisco, Francesco, Liberale, Luca, Bengs, Susan, Akhmedov, Alexander, Montecucco, Fabrizio, Beer, Jürg H., Lüscher, Thomas F., Bongiovanni, Dario, Camici, Giovanni G.

“…Hutchinson-Gilford Progeria Syndrome (HGPS) is an ultra-rare premature aging genetic disorder caused by a point mutation in the lamin A gene, LMNA. Children…”
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Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke by Bonetti, Nicole R., Liberale, Luca, Akhmedov, Alexander, Pasterk, Lisa, Gobbato, Sara, Puspitasari, Yustina M., Vukolic, Ana, Saeedi Saravi, Seyed Soheil, Coester, Bernd, Horvath, Carla, Osto, Elena, Montecucco, Fabrizio, Lüscher, Thomas F., Beer, Jürg H., Camici, Giovanni G.

“…Early revascularization -the gold standard therapy for ischemic stroke- is often withheld in the elderly population due to high risk of complications. Thus,…”
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Antithrombotic properties of Tafamidis: An additional protective effect for transthyretin amyloid cardiomyopathy patients by Ministrini, Stefano, Niederberger, Rebecca, Akhmedov, Alexander, Beer, Georgia, Puspitasari, Yustina M., Franzini, Maria, Vergaro, Giuseppe, Cannie, Douglas E., Elliott, Perry, Kahr, Peter C., Hock, Christoph, Kobza, Richard, Toggweiler, Stefan, Lüscher, Thomas F., Camici, Giovanni G., Stämpfli, Simon F.

“…Tafamidis is a molecular chaperone that stabilizes the transthyretin (TTR) homo-tetramer, preventing its dissociation and consequent deposition as amyloid…”
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Long non-coding RNAs H19 and NKILA are associated with the risk of death and lacunar stroke in the elderly population by Lapikova-Bryhinska, Tetiana, Ministrini, Stefano, Puspitasari, Yustina M., Kraler, Simon, Mohamed, Shafeeq Ahmed, Costantino, Sarah, Paneni, Francesco, Khetsuriani, Michael, Bengs, Susan, Liberale, Luca, Montecucco, Fabrizio, Krampla, Wolfgang, Riederer, Peter, Hinterberger, Margareta, Fischer, Peter, Lüscher, Thomas F., Grünblatt, Edna, Akhmedov, Alexander, Camici, Giovanni G.

“…•In a population of non-institutionalized 75 years-old subjects, lncRNA H19 predicts all-cause mortality over a follow-up of 14 years.•lncRNA H19 is…”
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Microvesicles released from activated CD4+ T cells alter microvascular endothelial cell function by Vdovenko, Daria, Balbi, Carolina, Di Silvestre, Dario, Passignani, Giulia, Puspitasari, Yustina M., Zarak‐Crnkovic, Martina, Mauri, Pierluigi, Camici, Giovanni G., Lüscher, Thomas F., Eriksson, Urs, Vassalli, Giuseppe

“…Background Microvesicles are vesicles shed by plasma membranes following cell activation and apoptosis. The role of lymphocyte‐derived microvesicles in…”
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Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre‐ and end‐stage heart failure by Hoogen, Patricia, Jager, Saskia C. A., Huibers, Manon M. H., Schoneveld, Arjan H., Puspitasari, Yustina M., Valstar, Gideon B., Oerlemans, Marish I. F. J., Weger, Roel A., Doevendans, Pieter A., Ruijter, Hester M., Laman, Jon D., Vink, Aryan, Sluijter, Joost P. G.

“…The chronic inflammatory response plays an important role in adverse cardiac remodelling and the development of heart failure (HF). There is also evidence that…”
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