Search Results - "Puspita, Lesly"

Oxidative stress and cellular pathologies in Parkinson's disease by Puspita, Lesly, Chung, Sun Young, Shim, Jae-Won

“…Parkinson's disease (PD) is a chronic and progressive neurodegeneration of dopamine neurons in the substantia nigra. The reason for the death of these neurons…”
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Advances in human pluripotent stem cell reporter systems by Puspita, Lesly, Juwono, Virginia Blessy, Shim, Jae-won

“…The capability of human pluripotent stem cells (hPSCs) to self-renew and differentiate into any cell type has greatly contributed to the advancement of…”
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Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation by Chung, Sun Young, Kishinevsky, Sarah, Mazzulli, Joseph R., Graziotto, John, Mrejeru, Ana, Mosharov, Eugene V., Puspita, Lesly, Valiulahi, Parvin, Sulzer, David, Milner, Teresa A., Taldone, Tony, Krainc, Dimitri, Studer, Lorenz, Shim, Jae-won

“…Parkinson's disease (PD) is characterized by the selective loss of dopamine neurons in the substantia nigra; however, the mechanism of neurodegeneration in PD…”
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Autophagy controls neuronal differentiation by regulating the WNT-DVL signaling pathway by Vidyawan, Vincencius, Puspita, Lesly, Juwono, Virginia Blessy, Deline, Magdalena, Pieknell, Kelvin, Chang, Mi-Yoon, Lee, Sang-Hun, Shim, Jae-Won

“…Macroautophagy/autophagy dysregulation is associated with various neurological diseases, including Vici syndrome. We aimed to determine the role of autophagy…”
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Generation of caudal-type serotonin neurons and hindbrain-fate organoids from hPSCs by Valiulahi, Parvin, Vidyawan, Vincencius, Puspita, Lesly, Oh, Youjin, Juwono, Virginia Blessy, Sittipo, Panida, Friedlander, Gilgi, Yahalomi, Dayana, Sohn, Jong-Woo, Lee, Yun Kyung, Yoon, Jeong Kyo, Shim, Jae-won

“…Serotonin (5-HT) neurons, the major components of the raphe nuclei, arise from ventral hindbrain progenitors. Based on anatomical location and axonal…”
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In vitro generation of mature midbrain-type dopamine neurons by adjusting exogenous Nurr1 and Foxa2 expressions to their physiologic patterns by 김태호, 송재진, Lesly Puspita, Parvin Valiulahi, 심재원, 이상훈

“…Developmental information aids stem cell biologists in producing tissue-specific cells. Recapitulation of the developmental profile of a specific cell type in…”
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In vitro generation of mature midbrain-type dopamine neurons by adjusting exogenous Nurr1 and Foxa2 expressions to their physiologic patterns by Kim, Taeho, Song, Jae-Jin, Puspita, Lesly, Valiulahi, Parvin, Shim, Jae-won, Lee, Sang-Hun

“…Developmental information aids stem cell biologists in producing tissue-specific cells. Recapitulation of the developmental profile of a specific cell type in…”
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Efficient Neural Differentiation of hPSCs by Extrinsic Signals Derived from Co-cultured Neural Stem or Precursor Cells by Rhee, Yong-Hee, Puspita, Lesly, Sulistio, Yanuar Alan, Kim, Seung Won, Vidyawan, Vincencius, Elvira, Rosalie, Chang, Mi-Yoon, Shim, Jae-won, Lee, Sang-Hun

“…In this study, we found that undifferentiated human pluripotent stem cells (hPSCs; up to 30% of total cells) present in the cultures of neural stem or…”
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