Search Results - "Pusnik, Mascha"
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Mitochondrial protein import receptors in Kinetoplastids reveal convergent evolution over large phylogenetic distances
Published in Nature communications (26-03-2015)“…Mitochondrial protein import is essential for all eukaryotes and mediated by hetero-oligomeric protein translocases thought to be conserved within all…”
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2
Mitochondrial Preprotein Translocase of Trypanosomatids Has a Bacterial Origin
Published in Current biology (25-10-2011)“…Mitochondria are found in all eukaryotic cells and derive from a bacterial endosymbiont [ 1, 2]. The evolution of a protein import system was a prerequisite…”
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3
Trypanosomal Pentatricopeptide Repeat Protein Stabilizes the Mitochondrial mRNAs of Cytochrome Oxidase Subunits 1 and 2
Published in Eukaryotic Cell (2012)“…The pentatricopeptide repeat (PPR) protein family consists of organellar proteins predicted to bind to specific RNA sequences. Plants have hundreds of distinct…”
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4
Pentatricopeptide Repeat Proteins in Trypanosoma brucei Function in Mitochondrial Ribosomes
Published in Molecular and Cellular Biology (01-10-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Trypanosomal TAC40 constitutes a novel subclass of mitochondrial β-barrel proteins specialized in mitochondrial genome inheritance
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2014)“…Mitochondria cannot form de novo but require mechanisms allowing their inheritance to daughter cells. In contrast to most other eukaryotes Trypanosoma brucei…”
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6
canonical pathway for selenocysteine insertion is dispensable in Trypanosomes
Published in Proceedings of the National Academy of Sciences - PNAS (31-03-2009)“…The micronutrient selenium is found in proteins as selenocysteine (Sec), the 21st amino acid cotranslationally inserted in response to a UGA codon. In vitro…”
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7
The agar diffusion scratch assay - A novel method to assess the bioactive and cytotoxic potential of new materials and compounds
Published in Scientific reports (10-02-2016)“…A profound in vitro evaluation not only of the cytotoxic but also of bioactive potential of a given compound or material is crucial for predicting potential…”
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8
Bacterial origin of a mitochondrial outer membrane protein translocase: new perspectives from comparative single channel electrophysiology
Published in The Journal of biological chemistry (07-09-2012)“…Mitochondria are of bacterial ancestry and have to import most of their proteins from the cytosol. This process is mediated by Tom40, an essential protein that…”
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An essential novel component of the noncanonical mitochondrial outer membrane protein import system of trypanosomatids
Published in Molecular biology of the cell (01-09-2012)“…The mitochondrial outer membrane protein Tom40 is the general entry gate for imported proteins in essentially all eukaryotes. Trypanosomatids lack Tom40,…”
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10
Elongation factor 1a mediates the specificity of mitochondrial tRNA import in T. brucei
Published in The EMBO journal (17-10-2007)“…Mitochondrial tRNA import is widespread in eukaryotes. Yet, the mechanism that determines its specificity is unknown. Previous in vivo experiments using the…”
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The Single Mitochondrial Porin of Trypanosoma brucei is the Main Metabolite Transporter in the Outer Mitochondrial Membrane
Published in Molecular biology and evolution (01-03-2009)“…All mitochondria have integral outer membrane proteins with β-barrel structures including the conserved metabolite transporter VDAC (voltage dependent anion…”
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12
Bacterial Origin of a Mitochondrial Outer Membrane Protein Translocase
Published in The Journal of biological chemistry (07-09-2012)“…Mitochondria are of bacterial ancestry and have to import most of their proteins from the cytosol. This process is mediated by Tom40, an essential protein that…”
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13
Trypanosomal TAC40 constitutes a novel subclass of mitochondrial [Beta]-barrel proteins specialized in mitochondrial genome inheritance
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2014)“…Mitochondria cannot form de novo but require mechanisms allowing their inheritance to daughter cells. In contrast to most other eukaryotes Trypanosoma brucei…”
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14
Response to Zarsky et al
Published in Current biology (19-06-2012)“…Mitochondria evolved from an α-proteobacterial endosymbiont and recent phylogenetic and function-based research has demonstrated that the major pieces of the…”
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15
Isolation of mitochondria from procyclic Trypanosoma brucei
Published in Methods in molecular biology (Clifton, N.J.) (2007)“…The mitochondrion of the parasitic protozoon Trypanosoma brucei shows a number of unique features, many of which represent highly interesting research topics…”
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16
Type 3 peptide deformylases are required for oxidative phosphorylation in Trypanosoma brucei
Published in Molecular microbiology (01-09-2007)“…Summary Peptide deformylase (PDF) catalyses the removal of the formyl group from the first methionine of nascent proteins. Type 1 PDFs are found in bacteria…”
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