Search Results - "Purves, Robert"

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  1. 1

    Formation Of The Aqueous Humor by Macknight, Anthony Dc, McLaughlin, Charles W, Peart, David, Purves, Robert D, Carré, David A, Civan, Mortimer M

    “…SUMMARY 1. Glaucoma is a worldwide disease affecting approximately 1–2% of the population aged over 35 years in industrial countries and is a major cause of…”
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    Timolol may inhibit aqueous humor secretion by cAMP-independent action on ciliary epithelial cells by McLaughlin, C W, Peart, D, Purves, R D, Carré, D A, Peterson-Yantorno, K, Mitchell, C H, Macknight, A D, Civan, M M

    “…The beta-adrenergic antagonist timolol reduces ciliary epithelial secretion in glaucomatous patients. Whether inhibition is mediated by reducing cAMP is…”
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    Optimum numerical integration methods for estimation of area-under-the-curve (AUC) and area-under-the-moment-curve (AUMC) by Purves, R D

    “…Eleven numerical methods for estimation of AUC (including 4 new methods) and 22 methods for AUMC (including 8 new methods) were tested on large simulated noisy…”
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    Assembling a network to promote translational bladder cancer research in Canada by Koti, Madhuri, Berman, David M., Siemens, D. Robert, Lange, Dirk, Wang, Edwin, Toren, Paul, Eigl, Bernhard J., Hardy, Céline, Purves, Robert, Fradet, Vincent, Fradet, Yves, Mansure, Jose, Kassouf, Wassim, Black, Peter C.

    Published in Canadian Urological Association journal (14-09-2020)
    “…Bladder cancer research has historically lagged behind efforts in other disease sites with substantial underfunding relative to the heavy morbidity and…”
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    Effects of HCO3- on cell composition of rabbit ciliary epithelium: a new model for aqueous humor secretion by McLaughlin, CW, Peart, D, Purves, RD, Carre, DA, Macknight, AD, Civan, MM

    “…To determine whether the Na+-K+-2Cl- symport or the parallel Na+/H+ and Cl-/HCO3- antiports provide the dominant pathway for NaCl uptake into the ciliary…”
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    Numerical estimation of the noncompartmental pharmacokinetic parameters variance and coefficient of variation of residence times by Purves, R D

    Published in Journal of pharmaceutical sciences (01-02-1994)
    “…Noncompartmental investigation of the distribution of residence times from concentration-time data requires estimation of the second noncentral moment (AUM2C)…”
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    Electron Probe X-Ray Microanalysis of Rabbit Ciliary Epithelium by BOWLER, JOANNE M., PEART, DAVID, PURVES, ROBERT D., CARRÉ, DAVID A., MACKNIGHT, ANTHONY D.C., CIVAN, MORTIMER M.

    Published in Experimental eye research (01-02-1996)
    “…Rabbit iris–ciliary bodies were preincubated in control and experimental Ringer's solutions before quick freezing, cryosectioning, dehydration and electron…”
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    Bias and variance of extrapolated tails for area-under-the-curve (AUC) and area-under-the-moment-curve (AUMC) by Purves, R D

    “…The usual formulas for the extrapolated values of AUC and AUMC from tn to infinity produce estimates that are biased. An empirical correction factor is shown…”
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    The physics of iontophoretic pipettes by Purves, R D

    Published in Journal of neuroscience methods (01-08-1979)
    “…A theoretical study has been made of the release of drugs from iontophoretic pipettes. The chief predictions are: (1) in the steady state, release becomes…”
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