Search Results - "Pursell, Z. F."
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The high fidelity and unique error signature of human DNA polymerase
Published in Nucleic acids research (01-03-2011)Get full text
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Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase replication fidelity
Published in Nucleic acids research (16-02-2008)“…Replication of the mitochondrial genome by DNA polymerase γ requires dNTP precursors that are subject to oxidation by reactive oxygen species generated by the…”
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Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase
Published in Nucleic acids research (16-04-2007)“…To better understand the functions and fidelity of DNA polymerase [straight epsilon] (Pol [straight epsilon] ), we report here on the fidelity of yeast Pol…”
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Identification and Cloning of Two Histone Fold Motif-containing Subunits of HeLa DNA Polymerase ε
Published in The Journal of biological chemistry (28-07-2000)“…HeLa DNA polymerase ε (pol ε), possibly involved in both DNA replication and DNA repair, was previously isolated as a complex of a 261-kDa catalytic subunit…”
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DNA Precursor Asymmetries in Mammalian Tissue Mitochondria and Possible Contribution to Mutagenesis through Reduced Replication Fidelity
Published in Proceedings of the National Academy of Sciences - PNAS (05-04-2005)“…The mutation rate of the mammalian mitochondrial genome is higher than that of the nuclear genome. Because mitochondrial and nuclear deoxyribonucleoside…”
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Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase ε
Published in The Journal of biological chemistry (06-10-2000)Get full text
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