Search Results - "Purrello, M."

Identification of extracellular vesicles and characterization of miRNA expression profiles in human blastocoel fluid by Battaglia, R., Palini, S., Vento, M. E., La Ferlita, A., Lo Faro, M. J., Caroppo, E., Borzì, P., Falzone, L., Barbagallo, D., Ragusa, M., Scalia, M., D’Amato, G., Scollo, P., Musumeci, P., Purrello, M., Gravotta, E., Di Pietro, C.

“…In this study, for the first time, we demonstrated the presence of microRNAs and extracellular vesicles in human blastocoel fluid. The bioinformatic and…”
Get full text

Intracellular and extracellular miRNome deregulation in cellular models of NAFLD or NASH: Clinical implications by Di Mauro, S, Ragusa, M, Urbano, F, Filippello, A, Di Pino, A, Scamporrino, A, Pulvirenti, A, Ferro, A, Rabuazzo, A.M, Purrello, M, Purrello, F, Piro, S

“…Abstract Background & aims Nonalcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease in industrialized countries. NAFLD has the…”
Get full text

Cellular and molecular effects of protons: apoptosis induction and potential implications for cancer therapy by Di Pietro, C, Piro, S, Tabbì, G, Ragusa, M, Di Pietro, V, Zimmitti, V, Cuda, F, Anello, M, Consoli, U, Salinaro, E T, Caruso, M, Vancheri, C, Crimi, N, Sabini, M G, Cirrone, G A P, Raffaele, L, Privitera, G, Pulvirenti, A, Giugno, R, Ferro, A, Cuttone, G, Lo Nigro, S, Purrello, R, Purrello, F, Purrello, M

“…Due to their ballistic precision, apoptosis induction by protons could be a strategy to specifically eliminate neoplastic cells. To characterize the cellular…”
Get full text

Methicillin-resistant Staphylococcus aureus infections: A review of the currently available treatment options by Purrello, S.M., Garau, J., Giamarellos, E., Mazzei, T., Pea, F., Soriano, A., Stefani, S.

“…•Treatment options for MRSA among different types of infections are described.•Vancomycin remains a possible, but patient-tailored, option.•New…”
Get full text

Expression analysis of TFIID in single human oocytes: new potential molecular markers of oocyte quality by Di Pietro, C, Vento, M, Ragusa, M, Barbagallo, D, Guglielmino, MR, Maniscalchi, T, Duro, LR, Tomasello, L, Majorana, A, De Palma, A, Borzì, P, Scollo, P, Purrello, M

“…Abstract Molecular characterization of human female gametes should make it easier to understand the basis of certain infertility disorders. Biologically…”
Get full text

Molecular characterization of exosomes and their microRNA cargo in human follicular fluid: bioinformatic analysis reveals that exosomal microRNAs control pathways involved in follicular maturation by Santonocito, Manuela, Ph.D, Vento, Marilena, Ph.D, Guglielmino, Maria Rosa, Ph.D, Battaglia, Rosalia, M.Sc, Wahlgren, Jessica, Ph.D, Ragusa, Marco, Ph.D, Barbagallo, Davide, Ph.D, Borzì, Placido, M.D, Rizzari, Simona, M.Sc, Maugeri, Marco, Ph.D, Scollo, Paolo, M.D, Tatone, Carla, Ph.D, Valadi, Hadi, Ph.D, Purrello, Michele, M.D., Ph.D, Di Pietro, Cinzia, Ph.D

“…Objective To characterize well-represented microRNAs in human follicular fluid (FF) and to ascertain whether they are cargo of FF exosomes and whether they are…”
Get full text

MicroRNAs Are Stored in Human MII Oocyte and Their Expression Profile Changes in Reproductive Aging by Battaglia, Rosalia, Vento, Maria Elena, Ragusa, Marco, Barbagallo, Davide, La Ferlita, Alessandro, Di Emidio, Giovanna, Borzí, Placido, Artini, Paolo Giovanni, Scollo, Paolo, Tatone, Carla, Purrello, Michele, Di Pietro, Cinzia

“…Maternal RNAs are synthesized by the oocyte during its growth; some of them are utilized for oocyte-specific processes and metabolism, others are stored and…”
Get full text

Central venous catheter-related biofilm infections: An up-to-date focus on meticillin-resistant Staphylococcus aureus by Esposito, S., Purrello, S.M., Bonnet, E., Novelli, A., Tripodi, F., Pascale, R., Unal, S., Milkovich, G.

“…Central venous catheters are indispensable for the long-term treatment of seriously and chronically ill patients, but their use is often associated with a…”
Get full text

Nanogel-antimiR-31 conjugates affect colon cancer cells behaviour by Dispenza, C., Sabatino, M. A., Ajovalasit, A., Ditta, L. A., Ragusa, M., Purrello, M., Costa, V., Conigliaro, A., Alessandro, R.

“…Soft and flexible nanogels, produced by electron beam (e-beam) irradiation of poly( N -vinyl pyrrolidone) and acrylic acid, were evaluated as delivery devices…”
Get full text

Meticillin-resistant Staphylococcus aureus (MRSA) update: New insights into bacterial adaptation and therapeutic targets by Purrello, S.M., Daum, R.S., Edwards, G.F.S., Lina, G., Lindsay, J., Peters, G., Stefani, S.

“…Successful meticillin-resistant Staphylococcus aureus (MRSA) clones have evolved to adapt to healthcare, community and livestock environments. This review will…”
Get full text

A Novel Silicon Platform for Selective Isolation, Quantification, and Molecular Analysis of Small Extracellular Vesicles by Leonardi, Antonio Alessio, Battaglia, Rosalia, Morganti, Dario, Lo Faro, Maria Josè, Fazio, Barbara, De Pascali, Chiara, Francioso, Luca, Palazzo, Gerardo, Mallardi, Antonia, Purrello, Michele, Priolo, Francesco, Musumeci, Paolo, Di Pietro, Cinzia, Irrera, Alessia

“…Small extracellular vesicles (sEVs), thanks to their cargo, are involved in cellular communication and play important roles in cell proliferation, growth,…”
Get full text

Serum coding and non-coding RNAs as biomarkers of NAFLD and fibrosis severity by Scamporrino, A., Di Mauro, S., Petta, S., Urbano, F., Filippello, A., Ragusa, M., Di Martino, M.T., Scionti, F., Grimaudo, S., Pipitone, R.M., Privitera, G., Di Pino, A., Scicali, R., Rabuazzo, A.M., Craxì, A., Purrello, M., Purrello, F., Piro, S.

Get full text

miRNA profiling in vitreous humor, vitreal exosomes and serum from uveal melanoma patients: Pathological and diagnostic implications by Ragusa, Marco, Barbagallo, Cristina, Statello, Luisa, Caltabiano, Rosario, Russo, Andrea, Puzzo, Lidia, Avitabile, Teresio, Longo, Antonio, Toro, Mario D, Barbagallo, Davide, Valadi, Hadi, Di Pietro, Cinzia, Purrello, Michele, Reibaldi, Michele

“…Uveal melanoma (UM) represents approximately 5-6% of all melanoma diagnoses and up to 50% of patients succumb to their disease. Although several methods are…”
Get full text

Direct hybridization of labeled DNA to DNA in agarose gels by Purrello, M, Balazs, I

“…A fast and simple procedure for the hybridization of radioactive probes directly to DNA in agarose gels is described. Restriction endonuclease-digested DNA is…”
Get more information

Physical mapping at 6q27 of the locus for the TATA box-binding protein, the DNA-binding subunit of TFIID and a component of SL1 and TFIIIB, strongly suggests that it is single copy in the human genome by Purrello, M, Di Pietro, C, Mirabile, E, Rapisarda, A, Rimini, R, Tinè, A, Pavone, L, Motta, S, Grzeschik, K H, Sichel, G

“…The TATA box-binding protein (TBP) has a fundamental role in eukaryotic cell metabolism, since it is necessary for transcription of class I, class II, and…”
Get more information

Cytological Mapping of the Human Glucose-6-phosphate Dehydrogenase Gene Distal to the Fragile-X Site Suggests a High Rate of Meiotic Recombination across This Site by Szabo, Paul, Purrello, Michele, Rocchi, Mariano, Archidiacono, Nicoletta, Alhadeff, Becky, Filippi, Giorgio, Toniolo, Daniela, Martini, Giuseppe, Luzzatto, Lucio, Siniscalco, Marcello

“…The human gene for glucose-6-phosphate dehydrogenase (G6PD) has been subregionally mapped to band Xq28 by segregation analysis in rodent-human somatic cell…”
Get full text

Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: Possible role of oxidative stress by Piro, Salvatore, Anello, Marcello, Di Pietro, Cinzia, Lizzio, Maria Natalia, Patan[egrave], Giovanni, Rabuazzo, Agata Maria, Vigneri, Riccardo, Purrello, Michele, Purrello, Francesco

“…We investigated the effect of a chronic exposure to high levels of free fatty acid (FFA; 2 mmol/L oleate/palmitate 2:1) or glucose (16.7 mmol/L) on islet cell…”
Get full text

Nanogel-antimiR-31 conjugates affect colon cancer cells behaviourElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ra09797b by Dispenza, C, Sabatino, M. A, Ajovalasit, A, Ditta, L. A, Ragusa, M, Purrello, M, Costa, V, Conigliaro, A, Alessandro, R

“…Soft and flexible nanogels, produced by electron beam (e-beam) irradiation of poly( N -vinyl pyrrolidone) and acrylic acid, were evaluated as delivery devices…”
Get full text

Localization of the human genes encoding the two subunits of general transcription factor TFIIE by Purrello, M, Di Pietro, C, Rapisarda, A, Motta, S, Pavone, L, Grzeschik, K H, Sichel, G

“…TFIIE is a general transcription factor for class II genes composed of two types of subunits, a large one of 56 kDa and a small of 34 kDa. By Southern analysis…”
Get more information

Genetic characterization of general transcription factors TFIIF and TFIIB of Homo sapiens sapiens by Purrello, M, Di Pietro, C, Rapisarda, A, Mirabile, E, Motta, S, Sichel, G, Grzeschik, K H

“…Analysis of loci GTF2F1 and GTF2B, encoding Rap 74 (a subunit of TFIIF) and TFIIB, respectively, showed that they are present in a single copy in the human…”
Get more information