Search Results - "Puro, D G"

Energy Metabolism in Human Retinal Muller Cells by Winkler, Barry S, Arnold, Matthew J, Brassell, Melissa A, Puro, Donald G

“…To measure selected parameters of energy metabolism and adenosine triphosphate (ATP) production in passaged monolayer cultures of human retinal glial (Müller)…”
Get full text

Diabetes-Induced Disruption of Gap Junction Pathways within the Retinal Microvasculature by Oku, Hidehiro, Kodama, Tatsuo, Sakagami, Kenji, Puro, Donald G

“…Microvascular damage caused by diabetes is a leading cause of visual loss. Identifying events early in the course of diabetic retinopathy may help in…”
Get full text

Thrombin-induced inhibition of potassium currents in human retinal glial (Müller) cells by Puro, D G, Stuenkel, E L

“…1. Glial cells are known to play a role in regulating the microenvironment of the nervous system. While earlier considerations of glial function assumed a…”
Get full text

Activation of NMDA receptor-channels in human retinal Müller glial cells inhibits inward-rectifying potassium currents by Puro, D G, Yuan, J P, Sucher, N J

“…Although it is well known that neurotransmitters mediate neuron-to-neuron communication, it is becoming clear that neurotransmitters also affect glial cells…”
Get more information

Regulation of retinal glial cell proliferation by antiproliferative molecules by Ikeda, T., Puro, D.G.

“…Glial cells normally do not proliferate in the adult retina despite the presence of glial mitogens. In this study, we examined the hypothesis that endogenous…”
Get full text

PDGF-Induced Coupling of Function with Metabolism in Microvascular Pericytes of the Retina by Sakagami, Kenji, Kodama, Tatsuo, Puro, Donald G

“…The aim of this study was to test the hypothesis that platelet-derived growth factor (PDGF)-BB regulates the physiology of retinal pericytes, which are…”
Get full text

ATP: a vasoactive signal in the pericyte-containing microvasculature of the rat retina by Kawamura, Hajime, Sugiyama, Tetsuya, Wu, David M, Kobayashi, Masato, Yamanishi, Shigeki, Katsumura, Kozo, Puro, Donald G

“…In this study we tested the hypothesis that extracellular ATP regulates the function of the pericyte-containing retinal microvessels. Pericytes, which are more…”
Get full text

Intracellular ATP activates inwardly rectifying K+ channels in human and monkey retinal Müller (glial) cells by Kusaka, S, Puro, D G

“…1. In the vertebrate retina, the inwardly rectifying K+ (KIR) channels of the Müller (glial) cells are pathways for the redistribution of excess extracellular…”
Get full text

Glutamate as a neuron-to-glial signal for mitogenesis: role of glial N-methyl-D-aspartate receptors by Uchihori, Y, Puro, D G

“…The presence on glial cells of receptors for neurotransmitters suggests the capability of neuron-to-glial signalling. Here, we asked whether the retinal…”
Get more information

Mitogenic and chemotactic effects of platelet-derived growth factor on human retinal glial cells by Uchihori, Y, Puro, DG

“…Glial cell migration and proliferation appear to play a role in many of the proliferative retinopathies. Knowledge concerning the regulation of the migratory…”
Get full text

Modulation of calcium channels in human retinal glial cells by basic fibroblast growth factor: a possible role in retinal pathobiology by Puro, DG, Mano, T

“…The objective of this study was to begin to examine the cellular and biophysical effects on human retinal glial cells of basic fibroblast growth factor (bFGF),…”
Get full text

Phagocytosis by human retinal glial cells in culture by Mano, T, Puro, DG

“…Under a variety of pathologic conditions, glial cells of the retina are capable of phagocytosis. Although phagocytosis may play a role in retinal pathobiology,…”
Get full text

Retinal glial cell proliferation and ion channels: a possible link by Puro, DG, Roberge, F, Chan, CC

“…Under a variety of pathological conditions, glial cells of the retina proliferate. Although glial cell proliferation may play a role in a number of important…”
Get full text

Plasma-induced changes in the physiology of mammalian retinal glial cells: Role of glutamate by Kusaka, Shunji, Kapousta-Bruneau, Natalia V., Puro, Donald G.

“…Plasma can leak into the nervous system when the vascular endothelial barrier is compromised. Although this occurs commonly, little is known about the effects…”
Get full text

Nerve growth factor: a mitogenic signal for retinal Müller glial cells by Ikeda, T, Puro, D G

“…Knowledge of the effects of nerve growth factor (NGF) on glia is limited. A CNS site where NGF-glial interactions may occur is the retina. NGF is endogenous to…”
Get more information

Stretch-activated channels in human retinal Muller cells by Puro, D G

“…The cell-attached and excised patch configurations of the patch clamp technique were used to study stretch-activated ion channels in Muller glial cells that…”
Get more information

A calcium-activated, calcium-permeable ion channel in human retinal glial cells: modulation by basic fibroblast growth factor by Puro, D G

“…A calcium-permeable, voltage-insensitive non-specific cation channel that is activated by cytoplasmic calcium was found in approximately 50% of the…”
Get more information

Insulin-Mediated Regulation of Neuronal Maturation by Puro, Donald G., Agardh, Elisabet

“…Exposure to insulin increased stimulus-evoked transmission at synapses formed in culture by cholinergic retinal neurons derived from fetal rats. This effect…”
Get full text

Replication of human cytomegalovirus in human retinal glial cells by Burd, EM, Pulido, JS, Puro, DG, O'Brien, WJ

“…The purpose of these studies was to characterize the replication cycle of human cytomegalovirus (HCMV) in human retinal glial cells in vitro. Cultured human…”
Get full text

Physiology of rat retinal pericytes: modulation of ion channel activity by serum-derived molecules by Sakagami, Kenji, Wu, David M., Puro, Donald G.

“…Pericytes, which are contractile cells located on the outer wall of microvessels, are thought to be particularly important in the retina where the ratio of…”
Get full text