Search Results - "Purmer, Ilse M."
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Fluid balance-adjusted creatinine at initiation of continuous venovenous hemofiltration and mortality. A post-hoc analysis of a multicenter randomized controlled trial
Published in PloS one (06-06-2018)“…Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is associated with high mortality. The creatinine-based stage of AKI is considered when…”
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Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial
Published in Intensive care medicine (01-12-2022)“…Purpose Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has been proposed as an…”
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Effect of a Lower vs Higher Positive End-Expiratory Pressure Strategy on Ventilator-Free Days in ICU Patients Without ARDS: A Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (22-12-2020)“…IMPORTANCE: It is uncertain whether invasive ventilation can use lower positive end-expiratory pressure (PEEP) in critically ill patients without acute…”
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Citrate anticoagulation versus systemic heparinisation in continuous venovenous hemofiltration in critically ill patients with acute kidney injury: a multi-center randomized clinical trial
Published in Critical care (London, England) (16-08-2014)“…Because of ongoing controversy, renal and vital outcomes are compared between systemically administered unfractionated heparin and regional anticoagulation…”
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A narrative review of predictors for β-lactam antibiotic exposure during empirical treatment in critically ill patients
Published in Expert opinion on drug metabolism & toxicology (03-04-2021)“…: Emerging studies suggest that antibiotic pharmacokinetics (PK) are difficult to predict in critically ill patients. The high intra- and inter-patient PK…”
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Target attainment of beta-lactam antibiotics and ciprofloxacin in critically ill patients and its association with 28-day mortality
Published in Journal of critical care (13-09-2024)“…This study aims to assess pharmacodynamic target attainment in critically ill patients and identify factors influencing target attainment and mortality…”
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Reported transfusion‐related acute lung injury associated with solvent/detergent plasma – A case series
Published in Transfusion (Philadelphia, Pa.) (01-03-2022)“…Background Antibody‐mediated transfusion‐related acute lung injury (TRALI) is caused by donor HLA or HNA antibodies in plasma‐containing products. In the…”
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Adverse drug events caused by three high‐risk drug–drug interactions in patients admitted to intensive care units: A multicentre retrospective observational study
Published in British journal of clinical pharmacology (01-01-2024)“…Aims Knowledge about adverse drug events caused by drug–drug interactions (DDI‐ADEs) is limited. We aimed to provide detailed insights about DDI‐ADEs related…”
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Brain computer tomography in critically ill patients--a prospective cohort study
Published in BMC medical imaging (12-12-2012)“…Brain computer tomography (brain CT) is an important imaging tool in patients with intracranial disorders. In ICU patients, a brain CT implies an intrahospital…”
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The effect of computerised decision support alerts tailored to intensive care on the administration of high-risk drug combinations, and their monitoring: a cluster randomised stepped-wedge trial
Published in The Lancet (British edition) (03-02-2024)“…Drug–drug interactions (DDIs) can harm patients admitted to the intensive care unit (ICU). Yet, clinical decision support systems (CDSSs) aimed at helping…”
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Major clinical events, signs and severity assessment scores related to actual survival in patients who died from primary biliary cirrhosis. A long-term historical cohort study
Published in Hepato-gastroenterology (01-01-1999)“…One of the prognostic methods for survival in primary biliary cirrhosis (PBC) is the Mayo model, with a time-scale limited to 7 years. The aim of our study was…”
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