Search Results - "Purdon, Amy"

Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of human ORFs and identification of human genes affecting viral titer by Škalamera, Dubravka, Dahmer, Mareike, Purdon, Amy S, Wilson, Benjamin M, Ranall, Max V, Blumenthal, Antje, Gabrielli, Brian, Gonda, Thomas J

“…The bottleneck in elucidating gene function through high-throughput gain-of-function genome screening is the limited availability of comprehensive libraries…”
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A high-throughput platform for lentiviral overexpression screening of the human ORFeome by Škalamera, Dubravka, Ranall, Max V, Wilson, Benjamin M, Leo, Paul, Purdon, Amy S, Hyde, Carolyn, Nourbakhsh, Ehsan, Grimmond, Sean M, Barry, Simon C, Gabrielli, Brian, Gonda, Thomas J

“…In response to the growing need for functional analysis of the human genome, we have developed a platform for high-throughput functional screening of genes…”
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Cecal Microbiota Directly Affect Colitis Development in a Mouse Model of Induced Colitis by Movva, Ramya, Purdon, Amy S, Alabbas, Saleh Y, Cuiv, Paraic O, Florin, Timothy H, Oancea, Iulia

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An Antibiotic Cocktail that Results in a Dysbiotic Microbiome Improves Spontaneous Colitis in the Winnie Mouse by Movva, Ramya, Oancea, Iulia, Png, Chinwen, Purdon, Amy S, Alabbas, Saleh Y, Cuiv, Paraic O, Florin, Timothy H

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Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors by Smart, Chanel E, Askarian Amiri, Marjan E, Wronski, Ania, Dinger, Marcel E, Crawford, Joanna, Ovchinnikov, Dmitry A, Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T, Song, Sarah, Wiesner, Christiane, French, Juliet D, Dave, Richa K, da Silva, Leonard, Purdon, Amy, Andrew, Megan, Mattick, John S, Lakhani, Sunil R, Brown, Melissa A, Kellie, Stuart

“…The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has been implicated in a range of cancers, including breast cancer, yet…”
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Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera by Mullally, Ann, Bruedigam, Claudia, Poveromo, Luke, Heidel, Florian H., Purdon, Amy, Vu, Therese, Austin, Rebecca, Heckl, Dirk, Breyfogle, Lawrence J., Kuhn, Catherine Paine, Kalaitzidis, Demetrios, Armstrong, Scott A., Williams, David A., Hill, Geoff R., Ebert, Benjamin L., Lane, Steven W.

“…Interferon-α (IFNα) is an effective treatment of patients with myeloproliferative neoplasms (MPNs). In addition to inducing hematological responses in most MPN…”
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Ploidy as a biomarker for targeting metabolism in ovarian cancer by Whybird, Matthew, Purdon, Amy, Harding, Angus, Coward, Jermaine

“…Abstract only…”
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Tu1849 - Cecal Microbiota Directly Affect Colitis Development in a Mouse Model of Induced Colitis by Movva, Ramya, Purdon, Amy S., Alabbas, Saleh Y., Cuiv, Paraic O., Florin, Timothy H., Oancea, Iulia

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Tu1868 - An Antibiotic Cocktail that Results in a Dysbiotic Microbiome Improves Spontaneous Colitis in the Winnie Mouse by Movva, Ramya, Oancea, Iulia, Png, Chinwen, Purdon, Amy S., Alabbas, Saleh Y., Cuiv, Paraic O., Florin, Timothy H.

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Generation of a Genome Scale Lentiviral Vector Library for EF1[alpha] Promoter-Driven Expression of Human ORFs and Identification of Human Genes Affecting Viral Titer by Skalamera, Dubravka, Dahmer, Mareike, Purdon, Amy S, Wilson, Benjamin M, Ranall, Max V, Blumenthal, Antje, Gabrielli, Brian, Gonda, Thomas J

“…The bottleneck in elucidating gene function through high-throughput gain-of-function genome screening is the limited availability of comprehensive libraries…”
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Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development by Lane, Steven W., De Vita, Serena, Alexander, Kylie A., Karaman, Ruchan, Milsom, Michael D., Dorrance, Adrienne M., Purdon, Amy, Louis, Leeann, Bouxsein, Mary L., Williams, David A.

“…Hematopoietic stem cells (HSCs) interact with osteoblastic, stromal, and vascular components of the BM hematopoietic microenvironment (HM) that are required…”
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Expression and Function of the Protein Tyrosine Phosphatase Receptor J by Smart, Chanel E, Askarian Amiri, Marjan E, Wronski, Ania, Dinger, Marcel E, Crawford, Joanna, Ovchinnikov, Dmitry A, Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T, Song, Sarah, Wiesner, Christiane, French, Juliet D, Dave, Richa K, da Silva, Leonard, Purdon, Amy, Andrew, Megan, Mattick, John S, Lakhani, Sunil R, Brown, Melissa A, Kellie, Stuart

“…The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has been implicated in a range of cancers, including breast cancer, yet…”
Get full text