Search Results - "Purdon, A"
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Manipulation of biological cells using a microelectromagnet matrix
Published in Applied physics letters (09-08-2004)“…Noninvasive manipulation of biological cells inside a microfluidic channel was demonstrated using a microelectromagnet matrix. The matrix consists of two…”
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Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism
Published in Gut (01-01-2017)“…Mercaptopurine (MP) and pro-drug azathioprine are 'first-line' oral therapies for maintaining remission in IBD. It is believed that their pharmacodynamic…”
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Expression and Localization of Caveolin-1, and the Presence of Membrane Rafts, in Mouse and Guinea Pig Spermatozoa
Published in Developmental biology (15-12-2001)“…In somatic cells, caveolin-1 plays several roles in membrane dynamics, including organization of detergent-insoluble lipid rafts, trafficking of cholesterol,…”
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Dynamics of docosahexaenoic acid metabolism in the central nervous system : Lack of effect of chronic lithium treatment
Published in Neurochemical research (01-03-1999)“…Using a method and model developed in our laboratory to quantitatively study brain phospholipid metabolism, in vivo rates of incorporation and turnover of…”
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Energy consumption by phospholipid metabolism in mammalian brain
Published in Neurochemical research (01-12-2002)“…Until recently, brain phospholipid metabolism was thought to consume only 2% of the ATP consumed by the mammalian brain as a whole. In this paper, however, we…”
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Rapid synthesis and turnover of brain microsomal ether phospholipids in the adult rat
Published in Journal of lipid research (01-01-2002)“…The rates of synthesis, turnover, and half-lives were determined for brain microsomal ether phospholipids in the awake adult unanesthetized rat. A…”
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Relation between free fatty acid and acyl-CoA concentrations in rat brain following decapitation
Published in Neurochemical research (01-07-1997)“…To ascertain effects of total ischemia on brain phospholipid metabolism, anesthetized rats were decapitated and unesterified fatty acids and long chain…”
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Energy requirements for two aspects of phospholipid metabolism in mammalian brain
Published in Biochemical journal (15-10-1998)“…Previous estimates have placed the energy requirements of total phospholipid metabolism in mammalian brain at 2% or less of total ATP consumption. This low…”
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Multi-objective optimisation of the operation of a water distribution network
Published in Computer Aided Chemical Engineering (2013)“…The aim was to move water through the reservoir network in such a way as to meet consumer demands and level constraints, minimise the cost of electricity, and…”
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Book Chapter -
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Leak Identification in a Water Distribution Network using Sparse Flow Measurements
Published in Computer Aided Chemical Engineering (2013)“…A Linear Programming technique is proposed to balance the flows in a network, matching flow measurements where available. Where necessary, a “leak-out” flow is…”
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Book Chapter -
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Brain arachidonic acid incorporation and precursor pool specific activity during intravenous infusion of unesterified [3H]arachidonate in the anesthetized rat
Published in Journal of neurochemistry (01-08-1994)“…Brain fatty acid incorporation into phospholipids can be measured in vivo following intravenous injection of fatty acid tracer. However, to calculate a…”
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Journal Article -
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Mechanisms of cellular recruitment in aseptic loosening of prosthetic joint implants
Published in Calcified tissue international (01-10-1995)“…The association of macrophages engaged in polymethylmethacrylate (PMMA) particle phagocytosis with pockets of inflammatory cells is a pathognomonic feature of…”
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Cloning and Chromosomal Localization of a Gene Encoding a Novel Serine/Threonine Kinase Belonging to the Subfamily of Testis-Specific Kinases
Published in Genomics (San Diego, Calif.) (01-10-2001)“…Using reverse transcription–polymerase chain reaction (RT-PCR) with degenerate oligonucleotides corresponding to two highly conserved motifs within the protein…”
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Isolation and quantitation of long-chain acyl-coenzyme A esters in brain tissue by solid-phase extraction
Published in Analytical biochemistry (01-08-1994)“…Long-chain acyl-CoA's are important intermediates in fatty acid oxidation and phospholipid metabolism. For quantitative analysis of brain acyl-CoA's, and to…”
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Water provisioning in Kruger National Park alters elephant spatial utilisation patterns
Published in Journal of arid environments (01-06-2017)“…Water provisioning is a controversial yet common practice and its consequences for wildlife and vegetation have fuelled well-worn debates. Contradictory…”
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Specific activity of brain palmitoyl-CoA pool provides rates of incorporation of palmitate in brain phospholipids in awake rats
Published in Journal of neurochemistry (01-11-1995)“…In vivo rates of palmitate incorporation into brain phospholipids were measured in awake rats following programmed intravenous infusion of unesterified…”
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Journal Article -
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Selective Acceleration of Arachidonic Acid Reincorporation into Brain Membrane Phospholipid Following Transient Ischemia in Awake Gerbil
Published in Journal of neurochemistry (01-01-1998)“…: Awake gerbils were subjected to 5 min of forebrain ischemia by clamping the carotid arteries for 5 min and then allowing recirculation. Radiolabeled…”
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Micromanipulation of biological systems with microelectromagnets
Published in IEEE transactions on magnetics (01-07-2004)“…Micromanipulation of biological systems with microelectromagnets, a ring trap, and a matrix, was demonstrated. A ring trap is a circular conducting wire topped…”
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