Search Results - "Purdie, K J"

High-resolution genomic profiling of human papillomavirus-associated vulval neoplasia by Purdie, K J, Harwood, C A, Gibbon, K, Chaplin, T, Young, B D, Cazier, J B, Singh, N, Leigh, I M, Proby, C M

“…Background: The incidence of human papillomavirus-associated vulval neoplasia is increasing worldwide; yet the associated genetic changes remain poorly…”
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Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis by Proby, C. M., Purdie, K. J., Sexton, C. J., Purkis, P., Navsaria, H. A., Stables, J. N., Leigh, I. M.

“…: A unique series of epidermal cell lines representing different stages of malignant transformation were spontaneously derived from a single adult…”
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The promoter of a novel human papillomavirus (HPV77) associated with skin cancer displays UV responsiveness, which is mediated through a consensus p53 binding sequence by Purdie, Karin J., Pennington, Joanne, Proby, Charlotte M., Khalaf, Sahira, de Villiers, Ethel-Michelle, Leigh, Irene M., Storey, Alan

“…An aetiological role has been proposed for human papillomavirus (HPV) in skin carcinogenesis within the immunosuppressed patient population. To examine this…”
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The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas by Leufke, C, Leykauf, J, Krunic, D, Jauch, A, Holtgreve-Grez, H, Böhm-Steuer, B, Bröcker, E-B, Mauch, C, Utikal, J, Hartschuh, W, Purdie, K J, Boukamp, P

“…The incidence of skin cancer is increasing worldwide and cutaneous squamous cell carcinomas (SCCs) are associated with considerable morbidity and mortality,…”
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Malignant transformation of cutaneous lesions in renal allograft patients : a role for human papillomavirus ? by PURDIE, K. J, SEXTON, C. J, PROBY, C. M, GLOVER, M. T, WILLIAMS, A. T, STABLES, J. N, LEIGH, I. M

“…Renal allograft recipients are at greatly increased risk of developing squamous cell carcinomas. As these frequently arise adjacent to areas of multiple viral…”
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Retention of low copy number human papillomavirus DNA in cultured cutaneous and mucosal wart keratinocytes by Williams, A. T, Sexton, C. J, Sinclair, A. L, Purdie, K. J, Thomas, M. S, Hanna, N. A, Goh, B. T, Williams, D. M, Leigh, I. M

“…1 Department of Experimental Dermatology, 2 Department of Virology 3 Department of Genito-Urinary Medicine and 4 Department of Oral Pathology, The London…”
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Evidence for replication of epidermodysplasia verruciformis-Type human papillomaviruses in nonmelanoma skin cancers by Purdie, K J, Surentheran, T, Sterling, J C, Bell, L

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Human Papillomavirus Gene Expression in Cutaneous Squamous Cell Carcinomas from Immunosuppressed and Immunocompetent Individuals by Purdie, Karin J., Surentheran, Thirunavukarasu, Sterling, Jane C., Bell, Louise, McGregor, Jane M., Proby, Charlotte M., Harwood, Catherine A., Breuer, Judith

“…Epidermodysplasia verruciformis (EV)-type human papillomavirus (HPV) DNA have been detected by PCR in squamous cell carcinomas (SCC) from both organ transplant…”
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Hepatocyte growth factor-induced endothelial cell motility is mediated by the upregulation of inducible nitric oxide synthase expression by Purdie, Karin J., Whitley, Guy St.J., Johnstone, Alan P., Cartwright, Judith E.

“…Abstract Objectives: Hepatocyte growth factor (HGF) is an angiogenic mitogen which stimulates migration in various cell types and has been shown to induce the…”
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Retentin of low copy number human papillomavirus DNA in cultured cutaneous and mucosal wart keratinocytes by WILLIAMS, A. T, SEXTON, C. J, SINCLAIR, A. L, PURDIE, K. J, THOMAS, M. S, HANNA, N. A, GOH, B. T, WILLIAMS, D. M, LEIGH, I. M

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Human interleukin 3: effects on normal and leukemic cells by Barber, K E, Crosier, P S, Purdie, K J, Buchanan, J M, Cattermole, J A, Watson, J D, Gillis, S

“…The effects of recombinant human interleukin 3 (IL3) on normal bone marrow cells and human leukemic cells were studied. In clonal assays, IL3 supported the…”
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