Search Results - "Purdie, C. A."

Case definition terminology for paratuberculosis (Johne's disease) by Whittington, R J, Begg, D J, de Silva, K, Purdie, A C, Dhand, N K, Plain, K M

“…Paratuberculosis (Johne's disease) is an economically significant condition caused by Mycobacterium avium subsp. paratuberculosis. However, difficulties in…”
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Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study by PURDIE, C. A, QUINLAN, P, JORDAN, L. B, ASHFIELD, A, OGSTON, S, DEWAR, J. A, THOMPSON, A. M

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Variation in susceptibility of different breeds of sheep to Mycobacterium avium subspecies paratuberculosis following experimental inoculation by Begg, D J, Purdie, A C, de Silva, K, Dhand, N K, Plain, K M, Whittington, R J

“…Exposure to Mycobacterium avium subspecies paratuberculosis (MAP) does not always lead to Johne's disease. Understanding differences in disease susceptibility…”
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What are the characteristics of breast cancers misclassified as benign by quantitative ultrasound shear wave elastography? by Vinnicombe, S. J., Whelehan, P., Thomson, K., McLean, D., Purdie, C. A., Jordan, L. B., Hubbard, S., Evans, A. J.

“…Objectives Shear wave elastography (SWE) is a promising adjunct to greyscale ultrasound in differentiating benign from malignant breast masses. The purpose of…”
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Meta-analysis of sentinel node biopsy in ductal carcinoma in situ of the breast by Ansari, B., Ogston, S. A., Purdie, C. A., Adamson, D. J., Brown, D. C., Thompson, A. M.

“…Background: The need for sentinel lymph node (SLN) biopsy in patients with a preoperative diagnosis of ductal carcinoma in situ (DCIS) is debated. Advocates…”
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p53 mutation, deprivation and poor prognosis in primary breast cancer by Baker, L, Quinlan, P R, Patten, N, Ashfield, A, Birse-Stewart-Bell, L-J, McCowan, C, Bourdon, J-C, Purdie, C A, Jordan, L B, Dewar, J A, Wu, L, Thompson, A M

“…Background: The deprivation gap for breast cancer survival remains unexplained by stage at presentation, treatment, or co-morbidities. We hypothesised that p53…”
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High frequency of complex TP53 mutations in CNS metastases from breast cancer by Lo Nigro, C, Vivenza, D, Monteverde, M, Lattanzio, L, Gojis, O, Garrone, O, Comino, A, Merlano, M, Quinlan, P R, Syed, N, Purdie, C A, Thompson, A, Palmieri, C, Crook, T

“…Background: Brain metastasis from breast cancer is usually associated with a poor prognosis and early death. Alteration of p53 may contribute to malignant…”
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Thymocyte apoptosis induced by p53-dependent and independent pathways by Clarke, A. R, Purdie, C. A, Harrison, D. J, Morris, R. G, Bird, C. C, Hooper, M. L, Wyllie, A. H

“…Death by apoptosis is characteristic of cells undergoing deletion during embryonic development, T- and B-cell maturation and endocrine-induced atrophy…”
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Multiparameter DNA content analysis identifies distinct groups in primary breast cancer by Dayal, J H S, Sales, M J, Corver, W E, Purdie, C A, Jordan, L B, Quinlan, P R, Baker, L, ter Haar, N T, Pratt, N R, Thompson, A M

“…Background: Multiparameter flow cytometry is a robust and reliable method for determining tumour DNA content applicable to formalin-fixed paraffin-embedded…”
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Magnetic resonance imaging texture analysis classification of primary breast cancer by Waugh, S. A., Purdie, C. A., Jordan, L. B., Vinnicombe, S., Lerski, R. A., Martin, P., Thompson, A. M.

“…Objectives Patient-tailored treatments for breast cancer are based on histological and immunohistochemical (IHC) subtypes. Magnetic Resonance Imaging (MRI)…”
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Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study by Purdie, C A, Quinlan, P, Jordan, L B, Ashfield, A, Ogston, S, Dewar, J A, Thompson, A M

“…Background: Progesterone receptor (PR) expression assessment in early invasive breast cancer remains controversial. This study sought to re-evaluate PR…”
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Axillary lymph node core biopsy for breast cancer metastases — How many needle passes are enough? by Macaskill, E.J, Purdie, C.A, Jordan, L.B, Mclean, D, Whelehan, P, Brown, D.C, Evans, A

“…Aim To determine the diagnostic yield of each of three core passes when sampling abnormal lymph nodes in patients presenting with breast cancer. Materials and…”
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Magnetic resonance imaging texture analysis classification of primary breast cancer by Waugh, S. A., Purdie, C. A., Jordan, L. B., Vinnicombe, S., Lerski, R. A., Martin, P., Thompson, A. M.

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p53 expression in colorectal tumors by Purdie, CA, O'Grady, J, Piris, J, Wyllie, AH, Bird, CC

“…The expression of the nuclear phosphoprotein p53 was studied immunohistochemically in a series of 150 benign and malignant colorectal tumors. Using monoclonal…”
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Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene by Purdie, C A, Harrison, D J, Peter, A, Dobbie, L, White, S, Howie, S E, Salter, D M, Bird, C C, Wyllie, A H, Hooper, M L

“…In human tumourigenesis the tumour suppressor gene most commonly affected by mutation, inactivation or allele loss is p53. Loss of p53 function is associated…”
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Sheep and cattle exposed to Mycobacterium avium subspecies paratuberculosis exhibit altered total serum cholesterol profiles during the early stages of infection by Johansen, M.D., de Silva, K., Plain, K.M., Begg, D.J., Whittington, R.J., Purdie, A.C.

“…•Total serum cholesterol increased in both sheep and cattle soon after MAP exposure.•Conserved mechanism of total serum cholesterol elevation and disease…”
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Stiffness at shear-wave elastography and patient presentation predicts upgrade at surgery following an ultrasound-guided core biopsy diagnosis of ductal carcinoma in situ by Evans, A, Purdie, C.A, Jordan, L, Macaskill, E.J, Flynn, J, Vinnicombe, S

“…Aim The aim of this study is to establish predictors of invasion in lesions yielding an ultrasound-guided biopsy diagnosis of ductal carcinoma in situ (DCIS)…”
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Efficacy of tumoricidal agents in vitro and in vivo by Docherty, J G, McGregor, J R, Purdie, C A, Galloway, D J, O'Dwyer, P J

“…Implantation of exfoliated tumour cells can give rise to local recurrence of colorectal cancer and it has been recommended that the bowel lumen be lavaged with…”
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Specific faecal antibody responses in sheep infected with Mycobacterium avium subspecies paratuberculosis by Begg, D.J., de Silva, K., Plain, K.M., Purdie, A.C., Dhand, N., Whittington, R.J.

“…Many studies have examined the serum antibody response to Mycobacterium avium subspecies paratuberculosis (MAP) infection in cases of Johne's disease (JD), but…”
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Increased mortality in HER2 positive, oestrogen receptor positive invasive breast cancer: a population-based study by Purdie, C A, Baker, L, Ashfield, A, Chatterjee, S, Jordan, L B, Quinlan, P, Adamson, D J A, Dewar, J A, Thompson, A M

“…Background: This study assessed the impact of h uman e pidermal growth factor r eceptor 2 (HER2) status on the outcomes in an unselected population of breast…”
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