Search Results - "Puralewski, Rachel"
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Older molecular brain age in severe mental illness
Published in Molecular psychiatry (01-07-2021)“…Psychiatric disorders are associated with accelerated aging and enhanced risk for neurodegenerative disorders. Brain aging is associated with molecular,…”
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Sex differences in adult mood and in stress-induced transcriptional coherence across mesocorticolimbic circuitry
Published in Translational psychiatry (06-02-2020)“…Women are approximately two times as likely to be diagnosed with major depressive disorder (MDD) compared to men. While sex differences in MDD might be driven…”
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Opposite Molecular Signatures of Depression in Men and Women
Published in Biological psychiatry (1969) (01-07-2018)“…Major depressive disorder (MDD) affects women approximately twice as often as men. Women are three times as likely to have atypical depression, with…”
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The Emergence of Trait Anxiety During the First Year of Life in Rhesus Monkeys, and Its Associations With Developing Anxiety-Related Neural Circuitry
Published 01-01-2023“…When extreme, trait anxiety responses are indicative of later psychopathology development. Trait anxiety emerges in early childhood, likely dependent on…”
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Dissertation -
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Dynamic longitudinal relations between regional brain metabolism and stress-related blood cortisol during the first year of nonhuman primate life
Published in Psychoneuroendocrinology (01-07-2023)“…Hypothalamic-pituitary-adrenal(HPA)-activation is critical to the stress response, promoting adaptation and survival. To further understand the developmental…”
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Threat-induced cortisol is positively associated with white matter microarchitecture in infant rhesus monkeys
Published in Psychoneuroendocrinology (01-07-2023)“…Cortisol is a stress hormone that mediates key physiological responses to threatening situations and modulates neural systems. However, its impact on brain…”
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Sex-related factors influence expression of mood-related genes in the basolateral amygdala differentially depending on age and stress exposure
Published in Biology of sex differences (17-09-2016)“…Women are twice as likely to be diagnosed with major depressive disorder (MDD) compared to men, but the molecular mechanisms underlying this sex difference are…”
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FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk
Published in Frontiers in psychology (16-09-2015)“…The A allele of the FRAS1-related extracellular matrix protein 3 (FREM3) rs7676614 single nucleotide polymorphism (SNP) was linked to major depressive disorder…”
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